Top 100 The Binding of Isaac Videos With The Most Comments by Kate LovelymomoTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.The Binding of Isaac WotL Eternal Edition HARD [Episode 1]57The Binding of Isaac 2.The Binding of Isaac [Episode 1] Welcome to your doom!49The Binding of Isaac 3.Kate Live!- The Binding of Isaac with Northernlion [Episode 1]43The Binding of Isaac 4.The Binding of Isaac WotL Eternal Edition [Episode 2]31The Binding of Isaac 5.The Binding of Isaac WoftL Eternal Edition on Hard [Episode 12] YEAH!21The Binding of Isaac 6.The Binding of Isaac WotL Eternal Edition [Episode 8] Continue21The Binding of Isaac 7.The Binding of Isaac WotL Eternal Edition [Episode 3]18The Binding of Isaac 8.The Binding of Isaac WotL Eternal Edition [Episode 10]17The Binding of Isaac 9.The Binding of Isaac WotL Eternal Edition [Episode 11] blueberries15The Binding of Isaac 10.The Binding of Isaac WotL Eternal Edition [Episode 6]14The Binding of Isaac 11.The Binding of Isaac: WoTL Eternal Edition on Hard [Episode 13]14The Binding of Isaac 12.Kate Live!- The Binding of Isaac with Northernlion [Episode 2]13The Binding of Isaac 13.The Binding of Isaac WotL Eternal Edition [Episode 4]13The Binding of Isaac 14.The Binding of Isaac WotL Eternal Edition [Episode 7]12The Binding of Isaac 15.The Binding of Isaac WotL Eternal Edition [Episode 5]11The Binding of Isaac 16.The Binding of Isaac: WoTL Eternal Edition On Hard [Episode 14] I beat the game!!10The Binding of Isaac 17.Kate Live!- The Binding of Isaac with Northernlion [Episode 3]9The Binding of Isaac 18.The Binding of Isaac WotL Eternal Edition [Episode 9] Isaac!9The Binding of Isaac 19.The Binding of Isaac [Episode 2] Dr.Boom!2The Binding of Isaac Top 100 » 200 » 300 » 400 » 500