| 1. | The Binding of Isaac: Repentance Launch Trailer | 10,688 | | The Binding of Isaac: Rebirth
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| 2. | The Binding of Isaac Rebirth Teaser Trailer | 5,521 | | The Binding of Isaac: Rebirth
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| 3. | The Binding of Isaac: Afterbirth Release Date Teaser | 4,888 | | The Binding of Isaac: Rebirth
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| 4. | The Binding of Isaac: Rebirth Release Date Trailer | 4,612 | | The Binding of Isaac: Rebirth
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| 5. | The Binding of Isaac: Afterbirth+ Release Date Trailer | 4,225 | | The Binding of Isaac: Rebirth
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| 6. | The Binding of Isaac: Afterbirth+ The Forgotten Update | 2,655 | Vlog | The Binding of Isaac: Rebirth
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| 7. | Isaac Repentance | 2,617 | | The Binding of Isaac: Rebirth
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| 8. | The Binding of Isaac: Afterbirth Release Trailer | 2,249 | Preview | The Binding of Isaac: Rebirth
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| 9. | The Binding of Isaac: Repentance Physical Edition Teaser Trailer | 1,461 | | The Binding of Isaac: Rebirth
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| 10. | The Binding of Isaac: Repentance New Teaser Trailer | 1,085 | | The Binding of Isaac: Rebirth
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| 11. | Nintendo Switch The Binding of Isaac: Afterbirth+ Announcement Trailer | 864 | | The Binding of Isaac: Rebirth
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| 12. | RemiLore (Switch, PS4, Xbox One, Steam) Announcement Trailer! | 704 | | The Binding of Isaac: Rebirth
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| 13. | The Binding of Isaac: Repentance Physical Edition Teaser Trailer Updated | 638 | | The Binding of Isaac: Rebirth
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| 14. | The Binding of Isaac: Rebirth on Wii U Gamepad Preview | 358 | | The Binding of Isaac: Rebirth
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| 15. | Crystal Crisis Original Soundtrack: Ballos Theme | 338 | | The Binding of Isaac: Rebirth
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| 16. | The Binding of Isaac: Afterbirth+ PlayStation 4 Release Date Announcement Trailer | 286 | Let's Play | The Binding of Isaac: Rebirth
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| 17. | The Binding of Isaac: Afterbirth+ Coming to Xbox One | 242 | | The Binding of Isaac: Rebirth
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| 18. | The Binding of Isaac: Afterbirth+ Xbox One Launch Trailer | 228 | | The Binding of Isaac: Rebirth
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| 19. | The Binding of Isaac: Afterbirth PS4 pre-release Livestream | 186 | | The Binding of Isaac: Rebirth
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| 20. | RemiLore Developer Video 2: Gameplay System and Modes | 95 | | The Binding of Isaac: Rebirth
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| 21. | 1001Spikes New Challengers | 75 | | The Binding of Isaac: Rebirth
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| 22. | Crystal Crisis Original Soundtrack: Elise Theme | 39 | | The Binding of Isaac: Rebirth
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| 23. | Crystal Crisis Original Soundtrack: Colosseum Theme | 22 | | The Binding of Isaac: Rebirth
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| 24. | Official TBOI Item Guides No. 058: Book of Shadows | 335 | | The Binding of Isaac: Rebirth
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| 25. | Official TBOI Item Guides No. 122: Whore of Babylon | 227 | | The Binding of Isaac: Rebirth
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| 26. | Official TBOI Item Guides No. 051: Pentagram | 373 | | The Binding of Isaac: Rebirth
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| 27. | Official TBOI Item Guides No. 062: Charm of the Vampire | 338 | | The Binding of Isaac: Rebirth
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| 28. | Official TBOI Item Guides No. 068 Technology | 406 | | The Binding of Isaac: Rebirth
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| 29. | Official TBOI Item Guides No. 076: X-Ray Vision | 282 | | The Binding of Isaac: Rebirth
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| 30. | Official TBOI Item Guides No. 129: Bucket of Lard | 181 | | The Binding of Isaac: Rebirth
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| 31. | Official TBOI Item Guides No. 137: Remote Detonator | 179 | | The Binding of Isaac: Rebirth
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| 32. | Official TBOI Item Guides No. 120: Odd Mushroom | 200 | | The Binding of Isaac: Rebirth
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| 33. | Official TBOI Item Guides No. 114: Mom's Knife | 340 | | The Binding of Isaac: Rebirth
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| 34. | Official TBOI Item Guides No. 228: Mom's Perfume | 119 | | The Binding of Isaac: Rebirth
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| 35. | Official TBOI Item Guides No. 133: Guppy's Paw | 205 | | The Binding of Isaac: Rebirth
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| 36. | Official TBOI Item Guides No. 217: Mom's Wig | 120 | | The Binding of Isaac: Rebirth
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| 37. | Official TBOI Item Guides No. 247: BFFS! | 137 | | The Binding of Isaac: Rebirth
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| 38. | Official TBOI Item Guides No. 141: Pageant Boy | 213 | | The Binding of Isaac: Rebirth
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| 39. | Official TBOI Item Guides No. 182: Sacred Heart | 346 | | The Binding of Isaac: Rebirth
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| 40. | Official TBOI Item Guides No. 245: 20/20 | 186 | | The Binding of Isaac: Rebirth
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| 41. | Official TBOI Item Guides No. 165: Cat-O-Nine-Tails | 187 | | The Binding of Isaac: Rebirth
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| 42. | Official TBOI Item Guides No. 107: The Pinking Shears | 207 | | The Binding of Isaac: Rebirth
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| 43. | Official TBOI Item Guides No. 083: The Nail | 287 | | The Binding of Isaac: Rebirth
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| 44. | Official TBOI Item Guides No. 204: Fanny Pack | 122 | | The Binding of Isaac: Rebirth
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| 45. | Official TBOI Item Guides No. 203: Humbleing Bundle | 159 | | The Binding of Isaac: Rebirth
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| 46. | Official TBOI Item Guides No. 240: Experimental Treatment | 141 | | The Binding of Isaac: Rebirth
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| 47. | Official TBOI Item Guides No. 196: Squeezy | 158 | | The Binding of Isaac: Rebirth
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| 48. | Official TBOI Item Guides No. 139: Mom's Purse | 189 | | The Binding of Isaac: Rebirth
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| 49. | Official TBOI Item Guides No. 079: The Mark | 317 | | The Binding of Isaac: Rebirth
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| 50. | Official TBOI Item Guides No. 263: Clear Rune | 163 | | The Binding of Isaac: Rebirth
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| 51. | Official TBOI Item Guides No. 027: Wooden Spoon | 391 | | The Binding of Isaac: Rebirth
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| 52. | Official TBOI Item Guides No. 272: BBF | 100 | | The Binding of Isaac: Rebirth
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| 53. | Official TBOI Item Guides No. 244: Tech.5 | 132 | | The Binding of Isaac: Rebirth
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| 54. | Official TBOI Item Guides No. 232: Stop Watch | 160 | | The Binding of Isaac: Rebirth
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| 55. | Official TBOI Item Guides No. 223: Pyromaniac | 168 | | The Binding of Isaac: Rebirth
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| 56. | Official TBOI Item Guides No. 004: Cricket's Head | 626 | | The Binding of Isaac: Rebirth
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| 57. | Official TBOI Item Guides No. 035: The Necronomicon | 335 | | The Binding of Isaac: Rebirth
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| 58. | Official TBOI Item Guides No. 038: Tammy's Head | 318 | | The Binding of Isaac: Rebirth
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| 59. | Official TBOI Item Guides No. 264: Smart Fly | 101 | | The Binding of Isaac: Rebirth
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| 60. | Official TBOI Item Guides No. 271: Mystery Sack | 103 | | The Binding of Isaac: Rebirth
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| 61. | Official TBOI Item Guides No. 230: Abaddon | 139 | | The Binding of Isaac: Rebirth
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| 62. | Official TBOI Item Guides No. 065: Anarchist Cookbook | 328 | | The Binding of Isaac: Rebirth
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| 63. | Official TBOI Item Guides No. 042: Bob's Rotten Head | 358 | | The Binding of Isaac: Rebirth
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| 64. | Official TBOI Item Guides No. 147: Notched Axe | 190 | | The Binding of Isaac: Rebirth
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| 65. | Official TBOI Item Guides No. 110: Mom's Contacts | 213 | | The Binding of Isaac: Rebirth
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| 66. | Official TBOI Item Guides No. 052: Dr. Fetus | 440 | | The Binding of Isaac: Rebirth
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| 67. | Official TBOI Item Guides No. 234: Infestation 2 | 133 | | The Binding of Isaac: Rebirth
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| 68. | Official TBOI Item Guides No. 108: The Wafer | 281 | | The Binding of Isaac: Rebirth
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| 69. | Official TBOI Item Guides No. 106: Mr. Mega | 213 | | The Binding of Isaac: Rebirth
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| 70. | Official TBOI Item Guides No. 081: Dead Cat | 344 | | The Binding of Isaac: Rebirth
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| 71. | Official TBOI Item Guides No. 130: A Pony | 178 | | The Binding of Isaac: Rebirth
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| 72. | Official TBOI Item Guides No. 070: Growth Hormones | 333 | | The Binding of Isaac: Rebirth
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| 73. | Official TBOI Item Guides No. 037: Mr. Boom | 333 | | The Binding of Isaac: Rebirth
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| 74. | Official TBOI Item Guides No. 112: Guardian Angel | 215 | | The Binding of Isaac: Rebirth
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| 75. | Official TBOI Item Guides No. 189: SMB Super Fan | 148 | | The Binding of Isaac: Rebirth
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| 76. | Official TBOI Item Guides No. 050: Steven | 419 | | The Binding of Isaac: Rebirth
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| 77. | Official TBOI Item Guides No. 175: Dad's Key | 171 | | The Binding of Isaac: Rebirth
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| 78. | Official TBOI Item Guides No. 104: The Parasite | 269 | | The Binding of Isaac: Rebirth
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| 79. | Official TBOI Item Guides No. 064: Steam Sale | 378 | | The Binding of Isaac: Rebirth
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| 80. | The Binding of Isaac Repentance+ Beta Release Trailer | 3,936 | | The Binding of Isaac: Rebirth
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| 81. | Official TBOI Item Guides Nos. 022-026, 346, 456, 707 - Meals | 574 | | The Binding of Isaac: Rebirth
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| 82. | Official TBOI Item Guides No. 184: Holy Grail | 132 | | The Binding of Isaac: Rebirth
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| 83. | Official TBOI Item Guides No. 212: Guppy's Collar | 131 | | The Binding of Isaac: Rebirth
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| 84. | Official TBOI Item Guides No. 121: Odd Mushroom | 214 | | The Binding of Isaac: Rebirth
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| 85. | Official TBOI Item Guides No. 080: The Pact | 337 | | The Binding of Isaac: Rebirth
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| 86. | Official TBOI Item Guides No. 089: Spider Bite | 250 | | The Binding of Isaac: Rebirth
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| 87. | Official TBOI Item Guides No. 044: Teleport! | 312 | | The Binding of Isaac: Rebirth
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| 88. | Official TBOI Item Guides No. 198: Box | 162 | | The Binding of Isaac: Rebirth
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| 89. | Official TBOI Item Guides No. 127: Forget Me Now | 230 | | The Binding of Isaac: Rebirth
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| 90. | Official TBOI Item Guides No. 111: The Bean | 194 | | The Binding of Isaac: Rebirth
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| 91. | Official TBOI Item Guides No. 135: IV Bag | 175 | | The Binding of Isaac: Rebirth
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| 92. | Official TBOI Item Guides No. 055: Mom's Eye | 354 | | The Binding of Isaac: Rebirth
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| 93. | Official TBOI Item Guides No. 086: Monstro's Tooth | 257 | | The Binding of Isaac: Rebirth
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| 94. | Official TBOI Item Guides No. 180: The Black Bean | 125 | | The Binding of Isaac: Rebirth
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| 95. | Official TBOI Item Guides No. 142: Scapular | 201 | | The Binding of Isaac: Rebirth
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| 96. | Official TBOI Item Guides No. 148: Infestation | 203 | | The Binding of Isaac: Rebirth
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| 97. | Official TBOI Item Guides No. 097: The Book of Sin | 216 | | The Binding of Isaac: Rebirth
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| 98. | Official TBOI Item Guides No. 102: Mom's Bottle of Pills | 220 | | The Binding of Isaac: Rebirth
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| 99. | Official TBOI Item Guides No. 193: MEAT! | 145 | | The Binding of Isaac: Rebirth
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| 100. | Official TBOI Item Guides No. 069: Chocolate Milk | 374 | | The Binding of Isaac: Rebirth
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