| 1. | Patrick and Sean | FirstSixty: Hellboy: The Science of Evil (PlayStation 3, Xbox 360) (Part 1) | 33,515 | Let's Play |
| 2. |  CapTV GAMEz | Играю в Hellboy The Science Of Evil - Обзор - Let's Play - Gameplay - Прохождение | 25,800 | Let's Play |
| 3. |  Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 1 - Witch Hunt | 5,326 | Let's Play |
| 4. | Patrick and Sean | FirstSixty: Hellboy: The Science of Evil (PlayStation 3, Xbox 360) (Part 2) | 3,974 | Let's Play |
| 5. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 2 - Obviously Offended Oni | 2,685 | Let's Play |
| 6. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 4 - Disgusting Discoveries | 1,899 | Let's Play |
| 7. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 3 - For Whom The Bell Tolls | 1,857 | Let's Play |
| 8. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 6 - Climactic Castle Confrontation | 1,755 | Let's Play |
| 9. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 5 - Wiggly Odd Round Monster | 1,689 | Let's Play |
| 10. |  MY RETRO DAYS | КОЛЛЕКЦИЯ ДИСКОВ PlayStation 3 - РАСПАКОВКА - Porkyfoot - СДЭК | 1,197 | Let's Play |
| 11. | Amazing Emulators | RPCS3 Playstation 3 Emulator - Hellboy: The Science of Evil (2008). Ingame. DirectX 12. Test #1 | 1,144 | Let's Play |
| 12. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 2.5 - Sewer Nazis | 928 | Let's Play |
| 13. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 3.5 - Spooky Nazis | 777 | Let's Play |
| 14. | Amazing Emulators | RPCS3 Playstation 3 Emulator - Hellboy: The Science of Evil (2008). Ingame. OpenGL. Test #2 | 713 | Let's Play |
| 15. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 5.5 - Magic Nazis | 667 | Let's Play |
| 16. | HrX Gamer Online | Hellboy The Science Of Evil || PlayStation 2 Game On Android || ppsspp 🎮 | 482 | Let's Play |
| 17. | Master Turkey | Hellboy: The Science of Evil - RPCS3 TEST | 433 | Let's Play |
| 18. | Addy Lovestar | Let's Play "Hellboy: The Science of Evil" - 4.5 - Cave Nazis | 367 | Let's Play |
| 19. |  Narwhal Entertainment | Let's Play Hellboy The Science of Evil Part 1: I AM THE GATEKEEPAH! | 353 | Let's Play |
| 20. | Jose Luis | Hellboy: The Science of Evil (Español) de Playstation Portable (PSP) con emulador PPSSPP. Gameplay | 322 | Let's Play |
| 21. |  JohnTMorton | Nostalgamer Unboxing Hellboy The Science Of Evil On Sony Playstation 3 Three UK PAL Version | 318 | Let's Play |
| 22. |  Braindead Entertainment | Hellboy: The Science of Evil PSP Playthrough - This Is Much Better Than IGN 3.0/10 Score | 234 | Let's Play |
| 23. |  FSXNOOB - 𝗚𝗔𝗠𝗘𝗦 & 𝗔𝗩𝗜𝗔𝗧𝗜𝗢𝗡 | Hellboy: The Science of Evil - Unfinished and sloppy | PSP Gameplay Moments 2008 HD | 217 | Let's Play |
| 24. | Zestran Plays | HELLBOY OF WAR - Hellboy: The Science of Evil PS3 Gameplay | 204 | Let's Play |
| 25. | Narwhal Entertainment | Let's Play Hellboy The Science of Evil Part 3: Nazi Monkey Robot | 166 | Let's Play |
| 26. | The Overshield | Niker Plays Hellboy The Science of Evil part 2 | 158 | Let's Play |
| 27. | Narwhal Entertainment | Let's Play Hellboy The Science of Evil Part 2: Head In A Tube | 152 | Let's Play |
| 28. | Narwhal Entertainment | Let's Play Hellboy The Science of Evil Part 4: Ding Dong The Witch is Dead | 124 | Let's Play |
| 29. | pewDmew | Hellboy: The Science of Evil (PS3) - Playthrough - No Commentary | 122 | Let's Play |
| 30. | Al Games Review | Hellboy: The Science of Evil ★ PlayStation 3 Game {{playable}} List ( RPCS3 - ASUS ROG ALLY) | 113 | Let's Play |
| 31. | The Overshield | Niker Plays: Hellboy: The Science of Evil Part 1 (I promise to finish) | 113 | Let's Play |
| 32. | Narwhal Entertainment | Let's Play Hellboy The Science of Evil Part 7: Cyborg Nazi Cthullu Monkey | 102 | Let's Play |
| 33. | Narwhal Entertainment | Let's Play Hellboy The Science of Evil Part 6: Elder-God | 90 | Let's Play |
| 34. |  Emu Andro | HellBoy: The Science Of Evil - Android Gameplay (PPSSPP Emulator) | 74 | Let's Play |
| 35. | Narwhal Entertainment | Let's Play Hellboy The Science of Evil Part 5: Indy-Action | 74 | Let's Play |
| 36. |  Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 1 | 55 | Let's Play |
| 37. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 12 Final Demon Ape and Von Klempt Boss fight | 32 | Let's Play |
| 38. | Retro Yoko | PS3 - HellBoy : The Science of Evil - #06 - FIN - | 30 | Let's Play |
| 39. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 3 | 30 | Let's Play |
| 40. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 8 | 26 | Let's Play |
| 41. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 7 | 25 | Let's Play |
| 42. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 6 | 21 | Let's Play |
| 43. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 10 | 20 | Let's Play |
| 44. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 2 | 19 | Let's Play |
| 45. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 5 | 16 | Let's Play |
| 46. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 4 | 15 | Let's Play |
| 47. | HowsItJoeIn | PPSSPP 1.10.3 | Hellboy: The Science of Evil HD | Sony PSP Emulator Gameplay | 14 | Let's Play |
| 48. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 9 | 14 | Let's Play |
| 49. | Surgical G | Let's Play - Hellboy : Science of Evil - Retro Thursday Night Stream | Retro nite | Chill vibes | 13 | Let's Play |
| 50. | flclafi | Hellboy: The Science of Evil In 2023 - Part 1 - Witch Hunt | Hellboy Games | 11 | Let's Play |
| 51. | flclafi | Hellboy: The Science of Evil - All Artifact Locations | 10 | Let's Play |
| 52. | Cheat Gamer | Hellboy The Science Of Evil Android gameplay part 11 | 10 | Let's Play |
| 53. | flclafi | Hellboy: The Science of Evil In 2023 - Part 5 - Buried Evil | Hellboy Games | 9 | Let's Play |
| 54. | flclafi | Hellboy: The Science of Evil In 2023 - Part 3 - The Witch Is Dead | Hellboy Games | 6 | Let's Play |
| 55. |  La Grotte d'Yves | HellBoy The science of evil #playstation3 #ps3 #gameplay | 4 | Let's Play |
| 56. |  VamBbyGirl | Finding a secret pathway to my Skelly Friend... | Hellboy: The Science of Evil | 3 | Let's Play |
