Loaded aka Blood Factory - ブラッドファクトリー (Quick Gameplay) Sega Saturn
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Loaded, known as Blood Factor in Japan, is an action game developed by Gremlin Interactive and published by Interplay for the Sega Saturn. It's played from a top-down perspective similar to games such as The Chaos Engine, but uses a mix of prerendered sprites and polygons to display the game world. 6 different characters are available for play. Gore content is very high.
The game had origins in DC Comics as well as the more adult-orientated Vertigo Comics, and there was a small graphic novel based on the game. The six playable characters of the game are a combination of villains, anti-heroes, psychopaths, perverts, mutants, and flamboyant murderers. They are, however, the best hope to stop the intergalactic supervillain nicknamed F.U.B. and save the universe. The characters were created and designed with contributions from Garth Ennis of Vertigo Comics and Greg Staples of 2000AD.