Top 100 The Binding of Isaac Videos With The Longest Duration by TheTurtleMelon
| Video Title | Duration | Category | Game | |
|---|---|---|---|---|
| 1. | (Stream VOD) OH NO - The Binding of Isaac Nuzlocke - Stream 4 | 2:14:15 | The Binding of Isaac | |
| 2. | HUGE Roguelike GIVEAWAY! 1000th Video Special! | 4:38 | The Binding of Isaac |