Top 100 The Binding of Isaac Videos With The Longest Duration by KyleCanGame
| Video Title | Duration | Category | Game | |
|---|---|---|---|---|
| 1. | THE BINDING OF ISAAC - SPEEDRUN CHALLENGE #6 HARDEST CHALLENGE YET. | 49:20 | The Binding of Isaac | |
| 2. | THE BINDING OF ISAAC* - NEW SPEEDRUN RECORD!!! KILL SATAN AND THE LAMB | 43:22 | The Binding of Isaac |