| 1. | Every Birthright Effect! - Part 2 #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 290,583 | | The Binding of Isaac: Rebirth
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| 2. | Every Birthright Effect! - Part 1 #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 261,574 | | The Binding of Isaac: Rebirth
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| 3. | Every Soul Stone Effect! #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac #tboi | 190,891 | | The Binding of Isaac: Rebirth
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| 4. | Glowing Hourglass Interactions! #shorts #isaacrepentance #bindingofisaacrepentance | 128,439 | | The Binding of Isaac: Rebirth
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| 5. | Death Certificate Interactions! #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 126,656 | | The Binding of Isaac: Rebirth
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| 6. | Fun Game Breaks in Isaac! #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac #tboi | 47,564 | | The Binding of Isaac: Rebirth
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| 7. | Best Characters for New Players! #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 42,253 | | The Binding of Isaac: Rebirth
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| 8. | My Favorite Items Per Character - Part 3, Cain #shorts #isaacrepentance #bindingofisaac #gaming | 36,690 | | The Binding of Isaac: Rebirth
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| 9. | Improving in Isaac: Hard Mode #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 35,140 | | The Binding of Isaac: Rebirth
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| 10. | Birthright Interactions! #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac #gaming | 33,787 | | The Binding of Isaac: Rebirth
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| 11. | Improving in Isaac: Settings #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 29,273 | | The Binding of Isaac: Rebirth
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| 12. | Improving in Isaac: Stop Resetting #shorts #bindingofisaacrepentance #isaacrepentance | 25,140 | | The Binding of Isaac: Rebirth
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| 13. | What Your FAVORITE Isaac Character Says About You - Part 1 #shorts #bindingofisaacrepentance #gaming | 24,487 | | The Binding of Isaac: Rebirth
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| 14. | Improving in Isaac: Health #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 20,462 | | The Binding of Isaac: Rebirth
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| 15. | My Favorite Items Per Character - Isaac, Part 1 #shorts #isaacrepentance #bindingofisaac #gaming | 19,655 | | The Binding of Isaac: Rebirth
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| 16. | Testing YOUR Synergies: Purgatory on Demand #shorts #bindingofisaacrepentance #bindingofisaac #tboi | 17,206 | | The Binding of Isaac: Rebirth
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| 17. | What Your FAVORITE Isaac Character Says About You - Part 2 #shorts #bindingofisaacrepentance #gaming | 16,060 | | The Binding of Isaac: Rebirth
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| 18. | One Bad Thing About Every Character in Isaac #shorts #isaacrepentance #bindingofisaacrepentance | 14,858 | | The Binding of Isaac: Rebirth
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| 19. | What Your FAVORITE Isaac Character Says About You - Part 5 #shorts #bindingofisaacrepentance #gaming | 14,228 | | The Binding of Isaac: Rebirth
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| 20. | Improving in Isaac: Devil Deals, Part 1 #shorts #bindingofisaacrepentance #bindingofisaac #gaming | 12,278 | | The Binding of Isaac: Rebirth
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| 21. | Teleport 2.0 Interactions! #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac #tboi | 12,019 | | The Binding of Isaac: Rebirth
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| 22. | One GOOD Thing About Every Character in Isaac! #shorts #isaacrepentance #bindingofisaacrepentance | 10,869 | | The Binding of Isaac: Rebirth
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| 23. | My Favorite Items Per Character - Part 2, Magdalene #shorts #isaacrepentance #bindingofisaac #gaming | 9,203 | | The Binding of Isaac: Rebirth
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| 24. | Red Key Interactions! #shorts #bindingofisaacrepentance #isaacrepentance #bindingofisaac | 7,274 | | The Binding of Isaac: Rebirth
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| 25. | What Your FAVORITE Isaac Character Says About You - Part 4 #shorts #bindingofisaacrepentance #gaming | 7,231 | | The Binding of Isaac: Rebirth
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| 26. | My Favorite Items Per Character - Part 4, Judas #shorts #isaacrepentance #bindingofisaac #gaming | 6,770 | | The Binding of Isaac: Rebirth
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| 27. | What Your FAVORITE Isaac Character Says About You - Part 6 #shorts #bindingofisaacrepentance #gaming | 6,092 | | The Binding of Isaac: Rebirth
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| 28. | What Your FAVORITE Isaac Character Says About You - Part 3 #shorts #bindingofisaacrepentance #gaming | 5,927 | | The Binding of Isaac: Rebirth
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| 29. | What Your FAVORITE Isaac Character Says About You - Part 7 #shorts #bindingofisaacrepentance #gaming | 4,474 | | The Binding of Isaac: Rebirth
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| 30. | What Your FAVORITE Isaac Character Says About You - Part 8 #shorts #bindingofisaacrepentance #gaming | 3,447 | | The Binding of Isaac: Rebirth
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| 31. | The Cursed Cain Run! (Random Save File Ep.8) | 2,137 | | The Binding of Isaac: Rebirth
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| 32. | What just happened? #shorts #tboi #thebindingofisaac #bindingofisaacrepentance #gaming | 2,111 | | The Binding of Isaac: Rebirth
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| 33. | Homing Shots Suck #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 1,785 | | The Binding of Isaac: Rebirth
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| 34. | Red Key Makes Basement OVERPOWERED! | 1,706 | | The Binding of Isaac: Rebirth
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| 35. | Blinded by the Light #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 1,502 | | The Binding of Isaac: Rebirth
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| 36. | How did I forget? #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 1,499 | | The Binding of Isaac: Rebirth
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| 37. | This mod is phenomenal! #shorts | 1,431 | | The Binding of Isaac: Rebirth
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| 38. | Pills are Energy! #shorts | 1,379 | | The Binding of Isaac: Rebirth
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| 39. | R U A Wizard is a good pill #shorts | 1,353 | | The Binding of Isaac: Rebirth
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| 40. | Instant Swallow #shorts | 1,270 | | The Binding of Isaac: Rebirth
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| 41. | It's for the content. #shorts | 1,233 | | The Binding of Isaac: Rebirth
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| 42. | Coupon Clutch! #shorts | 1,021 | | The Binding of Isaac: Rebirth
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| 43. | Brimstone Break #shorts | 1,014 | | The Binding of Isaac: Rebirth
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| 44. | Tilting off the face of the earth #shorts | 1,005 | | The Binding of Isaac: Rebirth
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| 45. | Yeah, you go Dark Bum! #shorts | 1,005 | | The Binding of Isaac: Rebirth
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| 46. | Don't Trust Pills #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 856 | | The Binding of Isaac: Rebirth
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| 47. | Pain brings laughter #shorts | 834 | | The Binding of Isaac: Rebirth
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| 48. | Yeah, alright, yep #shorts | 798 | | The Binding of Isaac: Rebirth
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| 49. | Double Matriarch! #shorts | 793 | | The Binding of Isaac: Rebirth
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| 50. | Soul Heart Central #shorts #gaming #bindingofisaacrepentance #isaacrepentance | 741 | | The Binding of Isaac: Rebirth
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| 51. | Cancer is so good! Short | 693 | | The Binding of Isaac: Rebirth
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| 52. | What do I do? #shorts | 625 | | The Binding of Isaac: Rebirth
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| 53. | There's a hole there! #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 625 | | The Binding of Isaac: Rebirth
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| 54. | 200% on Isaac, here we come! | 616 | | The Binding of Isaac: Rebirth
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| 55. | 4 Bombs for Nothing! #shorts #isaacrepentance #gaming #bindingofisaacrepentance | 554 | | The Binding of Isaac: Rebirth
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| 56. | Everyone loves Cursed Eye #shorts | 542 | | The Binding of Isaac: Rebirth
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| 57. | No! Wait.... actually? #shorts | 493 | | The Binding of Isaac: Rebirth
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| 58. | Thank you Bob's Brain! #shorts | 469 | | The Binding of Isaac: Rebirth
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| 59. | Disorientating #shorts | 446 | | The Binding of Isaac: Rebirth
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| 60. | This fight fit in a short #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 443 | | The Binding of Isaac: Rebirth
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| 61. | I am one with the game! #shorts | 437 | | The Binding of Isaac: Rebirth
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| 62. | Curse of the Maze! #shorts | 374 | | The Binding of Isaac: Rebirth
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| 63. | Shot Saturday! - The Isaac Drinking Game! | 373 | | The Binding of Isaac: Rebirth
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| 64. | Absolute Panic #shorts | 356 | | The Binding of Isaac: Rebirth
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| 65. | No Blood Bag After All That #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 350 | | The Binding of Isaac: Rebirth
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| 66. | My Dog Interrupts my Recording! #shorts | 338 | | The Binding of Isaac: Rebirth
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| 67. | Unboxing of Isaac: September 2022! | 333 | | The Binding of Isaac: Rebirth
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| 68. | Holy Shoot #shorts | 331 | | The Binding of Isaac: Rebirth
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| 69. | Never a Dull Moment in Isaac #shorts | 307 | | The Binding of Isaac: Rebirth
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| 70. | 30 Second Delirium! #shorts | 213 | | The Binding of Isaac: Rebirth
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| 71. | Bomb Flies always win #shorts | 198 | | The Binding of Isaac: Rebirth
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| 72. | This is rigged... #shorts | 164 | | The Binding of Isaac: Rebirth
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| 73. | Robert... #shorts | 144 | | The Binding of Isaac: Rebirth
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| 74. | I had HOW much damage early game?! (Random Save File Ep.9) | 141 | | The Binding of Isaac: Rebirth
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| 75. | Hope, Pray, and Scream #shorts | 136 | | The Binding of Isaac: Rebirth
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| 76. | Bestest Basement Boy! (Judas | Iron Man Challenge Ep.4) | 125 | | The Binding of Isaac: Rebirth
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| 77. | Achievement after achievement! (The Binding of Isaac - Random Save File Ep.1) | 117 | | The Binding of Isaac: Rebirth
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| 78. | This was harder than I thought... (Red | Rainbow Challenge Ep.1) | 111 | | The Binding of Isaac: Rebirth
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| 79. | Isaac without D6 is Still Easy! (Random Save File Ep.11) | 106 | | The Binding of Isaac: Rebirth
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| 80. | How to Make Tainted Maggie OVERPOWERED! | 97 | | The Binding of Isaac: Rebirth
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| 81. | Chaos is... actually good??? (Alternative Controller Ep.1 | Xbox Controller) | 95 | | The Binding of Isaac: Rebirth
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| 82. | Eve is a Good Character... in the Right Hands (The Binding of Isaac - Random Save File Ep.13) | 81 | | The Binding of Isaac: Rebirth
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| 83. | Health Upgrade Rant #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 78 | | The Binding of Isaac: Rebirth
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| 84. | I beat THIS Boss in 34 Seconds! (Azazel | Iron Man Challenge Ep. 8) | 72 | | The Binding of Isaac: Rebirth
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| 85. | You can play Isaac with a mouse?! (Alternative Controller Ep.2 | Mouse & Keyboard) | 70 | | The Binding of Isaac: Rebirth
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| 86. | Laz for the first time! (Random Save File Ep.7) | 68 | | The Binding of Isaac: Rebirth
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| 87. | We love Samson Runs! (Samson | Iron Man Challenge Ep.7) | 67 | | The Binding of Isaac: Rebirth
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| 88. | A completely normal run, nothing to see here (??? | Iron Man Challenge Ep 5) | 66 | | The Binding of Isaac: Rebirth
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| 89. | Best Azazel Run Ever?! (The Binding of Isaac - Random Save File Ep.2) | 65 | | The Binding of Isaac: Rebirth
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| 90. | Worst Room in the Game #shorts #gaming #isaacrepentance #bindingofisaacrepentance | 61 | | The Binding of Isaac: Rebirth
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| 91. | Third times the charm! (Red | Rainbow Challenge Ep.3) | 60 | | The Binding of Isaac: Rebirth
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| 92. | Lil Portal Trampoline! #shorts | 60 | | The Binding of Isaac: Rebirth
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| 93. | Can D6 save the day? It's looking grim... (Red | Rainbow Challenge Ep.2) | 59 | | The Binding of Isaac: Rebirth
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| 94. | Judas to Boss Rush and Hush is Free! (The Binding of Isaac - Random Save File Ep.14) | 58 | | The Binding of Isaac: Rebirth
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| 95. | Brainstorming Isaac Content, Favorite Items, and Biggest Content Challenges w/ @SacredsHearts | 57 | | The Binding of Isaac: Rebirth
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| 96. | They call me Devil Deal Daniel (Eve | Iron Man Challenge Ep 6) | 56 | | The Binding of Isaac: Rebirth
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| 97. | D6 Saves the Day! (Isaac | Iron Man Challenge Ep.1) | 51 | | The Binding of Isaac: Rebirth
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| 98. | I was crying like Isaac (Lazarus | The Binding of Isaac - Iron Man Challenge Ep. 9) | 48 | | The Binding of Isaac: Rebirth
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| 99. | So Many Soul Hearts! (Magdalene | Iron Man Challenge Ep.2) | 46 | | The Binding of Isaac: Rebirth
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| 100. | Two 5 Pip Dice Rooms?! (Random Save File Ep.6) | 46 | | The Binding of Isaac: Rebirth
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