| 401. | I have come back... | 0:00 | | The Binding of Isaac: Rebirth
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| 402. | Is Azazel ACTUALLY The Strongest Character? | 0:00 | | The Binding of Isaac: Rebirth
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| 403. | The BIGGEST Isaac Update Is REAL! | 0:00 | | The Binding of Isaac: Rebirth
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| 404. | They Buffed Damocles, It's Insane. | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 405. | This NEW Tech Item Is Stupidly BROKEN. | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 406. | How To Play Isaac CO-OP Online! | 0:00 | | The Binding of Isaac: Rebirth
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| 407. | This NEW MECHANIC Changes EVERYTHING! | 0:00 | | The Binding of Isaac: Rebirth
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| 408. | T. Jacob Is The Easiest Character, Here's Proof | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 409. | They FINALLY Released Mattman's Secret Mods! | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 410. | This Is The LUCKIEST Run You'll Ever See. | 0:00 | | The Binding of Isaac: Rebirth
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| 411. | The Journey To Unlock The Lost Begins | RTDG | 0:00 | | The Binding of Isaac: Rebirth
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| 412. | Breaking Isaac With The RISKIEST Synergy Ever! | 0:00 | | The Binding of Isaac: Rebirth
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| 413. | These NEW Planetarium Items Are MASSIVELY Broken. | 0:00 | | The Binding of Isaac: Rebirth
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| 414. | Can You Beat Isaac With The WORST Item In The Game? (Repentance+) | 0:00 | | The Binding of Isaac: Rebirth
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| 415. | ACTUALLY Rigged Youtuber Run: | 0:00 | | The Binding of Isaac: Rebirth
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| 416. | How To Make Isaac SMOOTHER Than Ever! | REPENTOGON | 0:00 | | The Binding of Isaac: Rebirth
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| 417. | Why T. Keeper Is The EASIEST Character Ever. | 0:00 | | The Binding of Isaac: Rebirth
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| 418. | I Made Isaac The STRONGEST 5yo EVER | #tboi #repentance #thebindingofisaac #isaac #gaming | 0:00 | | The Binding of Isaac: Rebirth
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| 419. | The Series Is Back, Now It Gets Hard. | 0:00 | | The Binding of Isaac: Rebirth
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| 420. | Taking Damage = Become Unstoppable | 0:00 | | The Binding of Isaac: Rebirth
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| 421. | How To INSTANTLY Break Any Isaac Run: | 0:00 | | The Binding of Isaac: Rebirth
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| 422. | COOP Isaac With Custom Builds! Ft. @KayhosYT | 0:00 | | The Binding of Isaac: Rebirth
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| 423. | 4x Dead God Player Ranks All Tainted Characters In Isaac! | Tierlist | 0:00 | | The Binding of Isaac: Rebirth
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| 424. | Why The Binding Of Isaac Is The Unreachable Roguelike | 0:00 | | The Binding of Isaac: Rebirth
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| 425. | These Mods Shouldn't Be Allowed. | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 426. | I Tried Isaac's Most BROKEN Challenge! | 0:00 | | The Binding of Isaac: Rebirth
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| 427. | I Proved Everyone Wrong About Tiny Planet. | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 428. | This Is What Peak Isaac Modding Looks Like: | 0:00 | | The Binding of Isaac: Rebirth
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| 429. | .. ... --. --- -. . | 0:00 | | The Binding of Isaac: Rebirth
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| 430. | Breaking Isaac With EVERY Quality4 Item In The FIRST FLOOR. | 0:00 | | The Binding of Isaac: Rebirth
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| 431. | Playing With Maggie's Birthright Was A Mistake. | The Binding Of Isaac Repentance+ | 0:00 | | The Binding of Isaac: Rebirth
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| 432. | The ULTIMATE Run Before Isaac Online Drops. | 0:00 | | The Binding of Isaac: Rebirth
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| 433. | The FIRST Modded Character Is HERE, And It's Broken! (Repentance+) | 0:00 | | The Binding of Isaac: Rebirth
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| 434. | 10 Minutes Of Isaac Breaking It Down | 0:00 | | The Binding of Isaac: Rebirth
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| 435. | Trying YOUR Strongest Synergies In Isaac #shorts #gaming #isaac #tboi #achievement | 0:00 | | The Binding of Isaac: Rebirth
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| 436. | HOW TO TRANSFER MODS TO ISAAC'S REPENTANCE+ | 0:00 | | The Binding of Isaac: Rebirth
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| 437. | Proving That T. Lost Is EASY. | Streaking | 0:00 | | The Binding of Isaac: Rebirth
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| 438. | This NEW Character Has INFINITE Potential | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 439. | How To PROPERLY Recover A Lost Savefile | Tutorial - The Binding Of Isaac Repentance+ | 0:00 | | The Binding of Isaac: Rebirth
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| 440. | This NEW CHARACTER Is Absolutely HILARIOUS, You'll Love him! | 0:00 | | The Binding of Isaac: Rebirth
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| 441. | I Tried The NEW Horsemen, They Are Wild. | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 442. | This NEW Knife Item Is BROKEN #mattman #thebindingofisaacrepentance #gaming #tboi #isaac #roguelike | 0:00 | | The Binding of Isaac: Rebirth
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| 443. | This NEW Item Oneshots EVERY Boss! | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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| 444. | Breaking My Mental Sanity With ONE Item. | The Binding Of Isaac Repentance | 0:00 | | The Binding of Isaac: Rebirth
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