| 301. | Binding of Isaac: Afterbirth Item guide - Head of the Keeper | 21 | | The Binding of Isaac: Rebirth
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| 302. | Binding of Isaac: Afterbirth Item guide - Endless Nameless | 21 | | The Binding of Isaac: Rebirth
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| 303. | Binding of Isaac: Afterbirth Item guide - Tractor Beam | 21 | | The Binding of Isaac: Rebirth
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| 304. | Binding of Isaac: Rebirth Item guide - Gimpy | 21 | | The Binding of Isaac: Rebirth
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| 305. | Binding of Isaac: Afterbirth Item guide - Farting Baby | 20 | | The Binding of Isaac: Rebirth
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| 306. | Binding of Isaac: Afterbirth Item guide - Faded Polaroid | 20 | | The Binding of Isaac: Rebirth
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| 307. | Binding of Isaac: Afterbirth Item guide - My Shadow | 20 | | The Binding of Isaac: Rebirth
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| 308. | Binding of Isaac: Afterbirth Item guide - Continuum | 19 | | The Binding of Isaac: Rebirth
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| 309. | Binding of Isaac: Rebirth Item guide - Abaddon | 19 | | The Binding of Isaac: Rebirth
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| 310. | Binding of Isaac: Afterbirth Item guide - No. 2 | 19 | | The Binding of Isaac: Rebirth
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| 311. | Binding of Isaac: Afterbirth Item guide - Athame | 19 | | The Binding of Isaac: Rebirth
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| 312. | Binding of Isaac: Afterbirth Item guide - Key Bum | 19 | | The Binding of Isaac: Rebirth
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| 313. | Binding of Isaac: Rebirth Item guide - Dead Cat | 19 | | The Binding of Isaac: Rebirth
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| 314. | Binding of Isaac: Rebirth Item guide - Fate | 19 | | The Binding of Isaac: Rebirth
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| 315. | Binding of Isaac: Rebirth Item guide - Tiny Planet | 19 | | The Binding of Isaac: Rebirth
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| 316. | Binding of Isaac: Rebirth Item guide - Mysterious Paper | 18 | | The Binding of Isaac: Rebirth
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| 317. | Binding of Isaac: Rebirth Item guide - Butter Bean | 17 | | The Binding of Isaac: Rebirth
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| 318. | Binding of Isaac: Afterbirth Item guide - Spider Mod | 17 | | The Binding of Isaac: Rebirth
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| 319. | Binding of Isaac: Afterbirth Item guide - Empty Vessel | 17 | | The Binding of Isaac: Rebirth
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| 320. | Binding of Isaac: Rebirth Item guide - Petrified Poop | 17 | | The Binding of Isaac: Rebirth
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| 321. | Binding of Isaac: Rebirth Item guide - Libra | 17 | | The Binding of Isaac: Rebirth
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| 322. | Binding of Isaac: Rebirth Item guide - Child's Heart | 17 | | The Binding of Isaac: Rebirth
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| 323. | Binding of Isaac: Rebirth Item guide - Purple Heart | 17 | | The Binding of Isaac: Rebirth
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| 324. | Binding of Isaac: Rebirth Item guide - A Lump Of Coal | 17 | | The Binding of Isaac: Rebirth
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| 325. | Binding of Isaac: Rebirth Item guide - Polyphemus | 16 | | The Binding of Isaac: Rebirth
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| 326. | Binding of Isaac: Afterbirth Item guide - Lazy Worm | 16 | | The Binding of Isaac: Rebirth
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| 327. | Binding of Isaac: Afterbirth Item guide - Evil Eye | 16 | | The Binding of Isaac: Rebirth
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| 328. | Binding of Isaac: Rebirth Item guide - The Body | 16 | | The Binding of Isaac: Rebirth
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| 329. | Binding of Isaac: Afterbirth Item guide - Sworn Protector | 16 | | The Binding of Isaac: Rebirth
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| 330. | Binding of Isaac: Rebirth Item guide - A Dollar | 16 | | The Binding of Isaac: Rebirth
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| 331. | Binding of Isaac: Rebirth Item guide - Tech.5 | 15 | | The Binding of Isaac: Rebirth
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| 332. | Binding of Isaac: Rebirth Item guide - The Sad Onion | 15 | | The Binding of Isaac: Rebirth
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| 333. | Binding of Isaac: Rebirth Item guide - The Bible | 15 | | The Binding of Isaac: Rebirth
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| 334. | Binding of Isaac: Rebirth Item guide - Pyromaniac | 15 | | The Binding of Isaac: Rebirth
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| 335. | Binding of Isaac: Rebirth Item guide - Number One | 15 | | The Binding of Isaac: Rebirth
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| 336. | Binding of Isaac: Rebirth Item guide - Cursed Skull | 15 | | The Binding of Isaac: Rebirth
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| 337. | Binding of Isaac: Rebirth Item guide - Strange Attractor | 15 | | The Binding of Isaac: Rebirth
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| 338. | Binding of Isaac: Rebirth Item guide - Forget Me Now | 14 | | The Binding of Isaac: Rebirth
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| 339. | Binding of Isaac: Rebirth Item guide - Holy Mantle | 14 | | The Binding of Isaac: Rebirth
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| 340. | Binding of Isaac: Afterbirth Item guide - Censer | 14 | | The Binding of Isaac: Rebirth
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| 341. | Binding of Isaac: Rebirth Item guide - Satanic Bible | 14 | | The Binding of Isaac: Rebirth
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| 342. | Binding of Isaac: Rebirth Item guide - D4 | 14 | | The Binding of Isaac: Rebirth
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| 343. | Binding of Isaac: Rebirth Item guide - Magic Mushroom | 14 | | The Binding of Isaac: Rebirth
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| 344. | Binding of Isaac: Afterbirth Item guide - D12 | 14 | | The Binding of Isaac: Rebirth
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| 345. | Binding of Isaac: Afterbirth Item guide - D7 | 13 | | The Binding of Isaac: Rebirth
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| 346. | Binding of Isaac: Afterbirth Item guide - Holy Light | 13 | | The Binding of Isaac: Rebirth
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| 347. | Binding of Isaac: Rebirth Item guide - How To Jump | 13 | | The Binding of Isaac: Rebirth
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| 348. | Binding of Isaac: Rebirth Item guide - Lucky Rock | 13 | | The Binding of Isaac: Rebirth
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| 349. | Binding of Isaac: Afterbirth Item guide - 8 Inch Nails | 13 | | The Binding of Isaac: Rebirth
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| 350. | Binding of Isaac: Rebirth Item guide - Aries | 13 | | The Binding of Isaac: Rebirth
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| 351. | Binding of Isaac: Rebirth Item guide - Broken Remote | 13 | | The Binding of Isaac: Rebirth
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| 352. | Binding of Isaac: Rebirth Item guide - Anti-Gravity | 13 | | The Binding of Isaac: Rebirth
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| 353. | Binding of Isaac: Afterbirth Item guide - Bomber Boy | 13 | | The Binding of Isaac: Rebirth
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| 354. | Binding of Isaac: Afterbirth Item guide - Purity | 13 | | The Binding of Isaac: Rebirth
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| 355. | Binding of Isaac: Afterbirth Item guide - Lusty Blood | 13 | | The Binding of Isaac: Rebirth
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| 356. | Burning Hush in hell - Binding of Isaac: Afterbirth | 13 | | The Binding of Isaac: Rebirth
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| 357. | Binding of Isaac: Rebirth Item guide - Steven | 13 | | The Binding of Isaac: Rebirth
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| 358. | Binding of Isaac: Rebirth Item guide - Transcendence | 13 | | The Binding of Isaac: Rebirth
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| 359. | Binding of Isaac: Afterbirth Item guide - Box of Friends | 13 | | The Binding of Isaac: Rebirth
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| 360. | Binding of Isaac: Rebirth Item guide - Bloof Of The Martyr | 13 | | The Binding of Isaac: Rebirth
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| 361. | Binding of Isaac: Afterbirth Item guide - Scatter Bombs | 12 | | The Binding of Isaac: Rebirth
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| 362. | Binding of Isaac: Rebirth Item guide - Mom's Pearl | 12 | | The Binding of Isaac: Rebirth
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| 363. | Binding of Isaac: Afterbirth Item guide - Lil' Chest | 12 | | The Binding of Isaac: Rebirth
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| 364. | Binding of Isaac: Afterbirth Item guide - Toxic Shock | 12 | | The Binding of Isaac: Rebirth
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| 365. | Binding of Isaac: Rebirth Item guide - Dry Baby | 12 | | The Binding of Isaac: Rebirth
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| 366. | Binding of Isaac: Rebirth Item guide - Holy Water | 12 | | The Binding of Isaac: Rebirth
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| 367. | Binding of Isaac: Rebirth Item guide - Wire Coat Hanger | 12 | | The Binding of Isaac: Rebirth
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| 368. | Binding of Isaac: Rebirth Item guide - Scapular | 12 | | The Binding of Isaac: Rebirth
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| 369. | Binding of Isaac: Afterbirth Item guide - Explosivo | 12 | | The Binding of Isaac: Rebirth
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| 370. | Binding of Isaac: Afterbirth Item guide - Shiny Rock | 12 | | The Binding of Isaac: Rebirth
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| 371. | Binding of Isaac: Rebirth Item guide - The Soul | 12 | | The Binding of Isaac: Rebirth
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| 372. | Binding of Isaac: Rebirth Item guide - Bluebaby's Only Friend | 12 | | The Binding of Isaac: Rebirth
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| 373. | Binding of Isaac: Rebirth Item guide - Cricket's Head | 12 | | The Binding of Isaac: Rebirth
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| 374. | Binding of Isaac: Afterbirth Item guide - Tear Detonator | 12 | | The Binding of Isaac: Rebirth
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| 375. | Binding of Isaac: Afterbirth Item guide - Fate's Reward | 12 | | The Binding of Isaac: Rebirth
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| 376. | Binding of Isaac: Rebirth Item guide - 1up! | 12 | | The Binding of Isaac: Rebirth
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| 377. | Binding of Isaac: Afterbirth Item guide - D8 | 12 | | The Binding of Isaac: Rebirth
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| 378. | Binding of Isaac: Rebirth Item guide - Dad's Key | 12 | | The Binding of Isaac: Rebirth
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| 379. | Binding of Isaac: Rebirth Item guide - The Mind | 11 | | The Binding of Isaac: Rebirth
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| 380. | Binding of Isaac: Rebirth Item guide - Mongo Baby | 11 | | The Binding of Isaac: Rebirth
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| 381. | Binding of Isaac: Afterbirth Item guide - Seraphim | 11 | | The Binding of Isaac: Rebirth
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| 382. | Binding of Isaac: Afterbirth Item guide - Glowing Hour Glass | 11 | | The Binding of Isaac: Rebirth
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| 383. | Binding of Isaac: Afterbirth Item guide - Betrayal | 11 | | The Binding of Isaac: Rebirth
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| 384. | Binding of Isaac: Rebirth Item guide - Samson's Chains | 11 | | The Binding of Isaac: Rebirth
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| 385. | Binding of Isaac: Afterbirth Item guide - Child Leash | 11 | | The Binding of Isaac: Rebirth
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| 386. | Binding of Isaac: Rebirth Item guide - The Ladder | 11 | | The Binding of Isaac: Rebirth
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| 387. | Binding of Isaac: Afterbirth Item guide - More Options | 11 | | The Binding of Isaac: Rebirth
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| 388. | Binding of Isaac: Afterbirth Item guide - GB Bug | 11 | | The Binding of Isaac: Rebirth
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| 389. | Binding of Isaac: Rebirth Item guide - Brother Bobby | 11 | | The Binding of Isaac: Rebirth
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| 390. | Binding of Isaac: Rebirth Item guide - Isaac's Head | 11 | | The Binding of Isaac: Rebirth
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| 391. | Binding of Isaac: Afterbirth Item guide - Placebo | 11 | | The Binding of Isaac: Rebirth
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| 392. | Binding of Isaac: Rebirth Item guide - Black Lipstick | 11 | | The Binding of Isaac: Rebirth
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| 393. | Binding of Isaac: Afterbirth Item guide - Dead Eye | 11 | | The Binding of Isaac: Rebirth
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| 394. | Binding of Isaac: Afterbirth Item guide - Serpent's Kiss | 11 | | The Binding of Isaac: Rebirth
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| 395. | Binding of Isaac: Rebirth Item guide - Technology | 11 | | The Binding of Isaac: Rebirth
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| 396. | Binding of Isaac: Rebirth Item guide - Judas' Shadow | 11 | | The Binding of Isaac: Rebirth
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| 397. | Binding of Isaac: Rebirth Item guide - Dead Onion | 11 | | The Binding of Isaac: Rebirth
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| 398. | Binding of Isaac: Rebirth Item guide - Punching Bag | 10 | | The Binding of Isaac: Rebirth
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| 399. | Binding of Isaac: Afterbirth Item guide - Lost Fly | 10 | | The Binding of Isaac: Rebirth
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| 400. | Binding of Isaac: Rebirth Item guide - Breakfast | 10 | | The Binding of Isaac: Rebirth
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