| 1. |  perpetuumworld | ПРОВОДИМ ОПЫТЫ И СОЗДАЕМ МУТАНТОВ ( Creature Lab ) | 552,096 | |
| 2. |  zbing z. | จับคนมาทำเป็นซอมบี้ | Creature Lab | 439,487 | |
| 3. |  Drae | Creating an Army of Mutants in My Mad Science Lab - Creature Lab | 398,742 | |
| 4. | Drae | Creating the Most Powerful Mutant in My Secret Laboratory - Creature Lab | 309,712 | |
| 5. | Drae | Creating an Undead Army in my Secret Laboratory - Creature Lab | 302,672 | |
| 6. |  Yippee Ki Yay Mr Falcon | Bioengineer Your Own Monster Girl Harem for World Domination | Creature Lab Gameplay | 258,933 | |
| 7. | Yippee Ki Yay Mr Falcon | Bioengineer a Monster Girl Harem as a Super Villain Scientist! - Creature Lab 1.0 | 173,500 | |
| 8. | Drae | Creating the Perfect Test Tube Mutant in My Creature Lab | 158,813 | |
| 9. |  Menos Trece | MI LABORATORIO DE CREACIÓN DE MUTANTES (Primer contacto) | CREATURE LAB Gameplay Español | 148,527 | |
| 10. | Drae | I Brewed the Perfect Military-Fighting Mutant in Creature Lab | 135,635 | |
| 11. |  GRamers | Vlog: Χτίζουμε Gaming PC με 1100 ευρώ (περίπου) | 135,495 | Vlog |
| 12. | GRamers | Gaming PC build ~ 1600 ευρώ (MSI, Corsair, Msystems) | 122,655 | |
| 13. | Drae | My Test Tube Mutants Have Taken Over the World - Creature Lab | 102,529 | |
| 14. |  KeysJore | PRAKTIKUM im LABOR von KREIS INDUSTRY - Creature Lab Deutsch | 94,854 | |
| 15. |  Dan Field | Creature Lab [FR] Créez des mutants, modifiez leur corps et envoyez les attaquer la ville! | 93,768 | |
| 16. | Beautiful OB | I Created Horrible MONSTERS in my CREATURE LAB?! | 90,048 | |
| 17. |  アフロマスク | 【Creature Lab】人間を魔改造して最強モンスターをつくる狂気に満ちた最新シミュレーターゲーム【アフロマスク 先行プレイ】 | 81,282 | |
| 18. | Mamkalo | دخلت مختبر كيميائي وحولت الناس إلى زومبي 🧟 Creature Lab 🔥 | 63,376 | |
| 19. | Yippee Ki Yay Mr Falcon | Surgically Enhance Your Monster Girl Harem Limb by Limb - Creature Lab 1.0 | 54,518 | |
| 20. |  Записи Стримов Блэка | Симулятор Прыгания по Гаражам / Creature Lab (демо) / Who Knocks / FAITH - Chapter II | 42,363 | |
| 21. | Dan Field | Creature Lab [FR] Créez des mutants dans votre laboratoire secret et envoyez les infecter le monde! | 41,406 | |
| 22. |  PlayWithRega | DOKTER GILA MENCIPTAKAN MONSTER CEWEK UNTUK DIJADIKAN HAREM TAKLUKAN DUNIA - Creature Lab | 35,422 | |
| 23. |  Sterzik | Ich habe PewDiePie erschaffen.. | Creature Lab | 33,230 | Let's Play |
| 24. | GameEdged | I Become a Mad Scientist | Creature Lab Gameplay | First Look | 32,830 | |
| 25. | DomPlays | A Reverse Horror Game Where I'm the Psychopath... | Creature Lab | 26,091 | |
| 26. | NutPinto | คนคลั่ง ดัดแปลงศพ | Creature Lab [คลิปเดียวจบ] | 25,170 | |
| 27. | RosGamer_xD | CREANDO MIS MONSTRUOS - CREATURE LAB DEMO | Gameplay Español | 22,263 | |
| 28. |  El DoQmentalista | Encuentran una extraña y horrible criatura llamada The Rake | 18,615 | |
| 29. | Yippee Ki Yay Mr Falcon | The Best Breeding & Evolving SCP Monster Girl Trainer : ( ͡° ͜ʖ ͡°) Edition | 18,353 | |
| 30. | Hii Channel | ห้องวิจัยลับ คืนชีพมนุษย์กลายพันธุ์ยึดโลก! | Creature Lab [DEMO] | 16,689 | |
| 31. | Grillmastah | Making Monsters In Frankenstein Simulator Fashion ~ Creature Lab | 10,854 | |
| 32. | Yippee Ki Yay Mr Falcon | The Most Ambitious Based Survival Horror 3D Game : Resident Evil At Home Edition | 10,652 | |
| 33. |  DualShot66 | Creature Lab Gameplay Walkthrough Part - 1 | 9,631 | Walkthrough |
| 34. | Grillmastah | Upgrading Our Equipment For More Mutations ~ Creature Lab | 9,338 | |
| 35. | Grillmastah | Making Ultimate Mutagen To Take Over The City ~ Creature Lab (END) | 8,590 | |
| 36. | Mr. Shko | Creature Lab | !!بە دلێ خۆت مەخلووقات دروستبکە | 8,400 | |
| 37. | Danny Jesden | EXPERIMENTIER MIT MENSCHEN IN DIESEM SPIEL !! | Creature Lab | 8,059 | |
| 38. | Grillmastah | Growing Limbs to Enhance Monsters ~ Creature Lab | 8,012 | |
| 39. | GameEdged | Mad Scientist Crafting Abominable Creatures | 7,985 | |
| 40. | Grillmastah | Mass Making Monsters For Experiments ~ Creature Lab | 7,911 | |
| 41. | GameEdged | This Experiment Went Terribly Wrong | 7,868 | Let's Play |
| 42. |  PLAGA | [18+] robię AGRESYWNEGO zombie w mojej PIWNICY - Creature Lab | 7,659 | |
| 43. |  Shota Vlogger | Creature Lab (Gameplay by ShotaVlogger) | 7,343 | |
| 44. | Yippee Ki Yay Mr Falcon | Mommy Milkers Literally : ¯\_(ツ)_/¯ Edition | 7,156 | |
| 45. |  Jack Shnaps | Creature Lab (ОПЫТЫ НАД ЛЮДЬМИ. Первый взгляд) - #1 | 7,108 | |
| 46. | Yippee Ki Yay Mr Falcon | Breed & Cook Meals Made Fro- FOR Humans In Your Cat Girl Diner : :3 Edition | 6,733 | |
| 47. | A2S Gaming | I Become a Mad Scientist | Creature Lab | Monster Girl Harem as a Super Villain Scientist! | 6,226 | |
| 48. | EVA GAMER | สร้างซอมบี้บุกโลก [Creature Lab] | 6,207 | |
| 49. | RosGamer_xD | CREANDO MIS MONSTRUOS - CREATURE LAB | Gameplay Español | 6,019 | |
| 50. | PlayWithRega | Ilmuwan Merubah Wanita Cantik Menjadi Monster | 5,897 | |
| 51. | PlayWithRega | GAME BARU MENCIPTAKAN MONSTER WANITA CANTIK UNTUK HAREM - Creature Lab Indonesia | 5,813 | |
| 52. | MinGamer.TV | Creature Lab สร้างสัตว์ประหลาดถล่มเมือง | 5,721 | |
| 53. | PLAGA | stworzyłem dwa NOWE potwory - Creature Lab | 5,469 | |
| 54. | Yippee Ki Yay Mr Falcon | I Can Fix Her : CURSED Flash Game Edition | 5,192 | |
| 55. | ThePlayWay | CREATURE LAB - Demo Trailer | 4,841 | |
| 56. | ThePlayWay | Creature Lab - Announcement Trailer | 4,832 | |
| 57. | Tamilan J | PUBG PC Tamil Live | Membership @29 RS | 4,808 | |
| 58. | Planet Bu | Creature Lab Gameplay // Full Demo // Walkthrough | 4,748 | Walkthrough |
| 59. | Yippee Ki Yay Mr Falcon | Breed & Evolve an SCP Monster Girl : Trainer Edition | 4,352 | |
| 60. | ThePlayWay | Creature Lab - Trailer #2 | 4,248 | |
| 61. | GameTrailers | Creature Lab - Official Xbox Trailer | 4,027 | |
| 62. | GameTrailers | Creature Lab - Official Console and Enhanced Edition Kickstarter Campaign Trailer | 3,850 | |
| 63. | Bonkol Live | Symulator tworzenia mutantów i kreatur - Creature Lab DEMO | 3,738 | |
| 64. | MrPanda | СОЗДАЮ МУТАНТОВ В СЕКРЕТНОЙ ЛАБОРАТОРИИ | 3,718 | |
| 65. | WildGamerSK | CREATURE LAB New Gameplay Demo 25 Minutes 4K | 3,617 | |
| 66. |  InsideAgameR | Creature Lab - Becoming A Mad Scientist - Nobody Can Stop My Mutants - Early Access Episode #1 | 3,358 | Show |
| 67. | GameTrailers | Creature Lab - Official Release Date Announcement Trailer | 2,964 | Preview |
| 68. | DBLTAP Shorts | Create nightmare inducing monsters to unleash #shorts | 2,693 | |
| 69. | GameTrailers | Creature Lab - Official Release Date Trailer | 2,521 | Preview |
| 70. | DieDevDie | Creating Mutant Army In Creature Lab | Impressions | 2,276 | |
| 71. | FullFamily | JE CRÉE DES MUTANTS DANS MON LABORATOIRE POUR DÉTRUIRE L'HUMANITÉ / Creature Lab | 2,221 | |
| 72. | Molotov Cocktail Gaming | 【最新作】狂った科学者が死体をゾンビ化して町を襲う！！【Creature Lab｜クリーチャーラボ】 | 2,210 | |
| 73. | Yo_Adrian! | Creating New Forms Of Life - Creature Lab | 2,197 | |
| 74. | Белый Ёжик | Creature Lab /Demo/ ➤ НАХИМИЧИЛ. | 1,966 | |
| 75. | BayDoesGames | *Make Scientist*, Not Love | 😆😹 Creature Lab Funny Moment #shorts #creaturelab | 1,885 | |
| 76. | DODI Gameplay | Creature Lab Gameplay | 1,843 | |
| 77. | Severete | CREATURE LAB - CREAMOS nuestros propios MUTANTES para INVADIR la CIUDAD | 1,681 | |
| 78. | InsideAgameR | Creature Lab - Becoming A Mad Scientist - Nobody Can Stop My Mutants - Early Access Episode #2 | 1,640 | Show |
| 79. | GRamers | Έμαθα Χημεία για να φτιάξω τέρατα στο Creature Lab | 1,615 | |
| 80. | 堪能メンなまあじ鯵人 | [なまあじ] ホラー実況 マッドサイエンティストになって化け物作ってみよう【CREATURE LAB／クリーチャーラボ（DEMO版）】 | 1,564 | |
| 81. | raXler Vision | Creature Lab - БЕЗУМНО СКУЧНЫЙ УЧЕНЫЙ | Обзор Демоверсии | 1,516 | |
| 82. | ThePlayWay | Creature Lab - Release Trailer STEAM | 1,499 | |
| 83. | SoraMix | Creature Lab เบื่อแล้ว ยิงซอมบี้ สร้าง ซอมบี้ ไปถล่มเมืองดีกว่า | 1,483 | |
| 84. | Omerta | СОЗДАЮ МОНСТРОВ / СИМУЛЯТОР ЗЛОДЕЯ / CREATURE LAB ПРОЗОЖДЕНИЕ #1 | 1,428 | |
| 85. | Digby C. Ceasar | Creature Lab demo - Let's Play! | 1,372 | |
| 86. | Ехидная 2д-тян [Vtuber] | 🔴 Я - безумный ученый??? [Creature Lab] #втубер #Ехидная #ruvtuber | 1,285 | |
| 87. | InsideAgameR | Creature Lab - Becoming A Mad Scientist - Nobody Can Stop My Mutants - Early Access Episode #3 | 1,138 | Show |
| 88. | Wee Hours Games | It's ALIVE!! | Creature Lab Demo (Mad Scientist Simulator) | 1,136 | |
| 89. | ThePlayWay | Creature Lab | Announcement Trailer | STEAM | 1,127 | |
| 90. |  Gameplay Channel [ITA] | CREIAMO CREATURE MOSTRUOSE! | Creature Lab | Full HD ITA | 1,112 | |
| 91. | DieDevDie | Who Wants To Be A Mutant? | #3 | Creature Lab | Livestream | 1,111 | |
| 92. | DieDevDie | Unknown 12 | #2 | Creature Lab | 1,075 | |
| 93. |  DT Gaming | CREATURE LAB - Official Gameplay Demo 2022 | 1,072 | |
| 94. | InsideAgameR | Creature Lab - Becoming A Mad Scientist - Nobody Can Stop My Mutants - Early Access Live Episode #4 | 1,069 | Show |
| 95. | ThePlayWay | Creature Lab - Playstation 5 Release Trailer | 1,020 | |
| 96. | GoEaSyTwitch | Creature Lab - Creare mostri? Si può! [Gameplay ITA] | 1,011 | |
| 97. | VR Bytes | Mutated Virus / Oculus Quest 2 [Meta] [App Lab] / Deutsch / First Impression / VR Spiele / Test | 962 | |
| 98. | Giannis Moschonas | Hentai Girl - A relaxed puzzle game with pretty waifu girls | 943 | |
| 99. | Newzkung Raccoonza | รังสรรค์ซอมบี้ สร้างกองทัพคนตายเสมือนจริง!? Creature Lab [Demo] | 898 | |
| 100. |  Fuzion Xbox Testing | Creature Lab - Xbox Series X Gameplay + FPS Test | 877 | |
