| 1. |  Hacksmith Industries | Mass Effect PLASMA RIFLE (Nerf Gun Mod) | 3,766,947 | |
| 2. | Matt McMuscles | Mass Effect Andromeda - What Happened? | 984,931 | |
| 3. | TetraNinja | Mass Effect Andromeda Walkthrough Part 1 - PATHFINDER (PC Ultra Let's Play Commentary) | 813,577 | Let's Play |
| 4. | VGS - Video Game Sophistry | Mass Effect Andromeda: Fem Ryder and Suvi romance gets AWKWARD | 388,341 | |
| 5. | SomeOrdinaryGamers | Mass Effect: Andromeda looks great... | 304,140 | |
| 6. | Gaming Ambience | Mass Effect: Andromeda - Galaxy Map Theme (2 Hours of Music) | 289,077 | |
| 7. | TetraNinja | Mass Effect Andromeda Walkthrough Part 2 - NEXUS LORE (PC Ultra Let's Play Commentary) | 272,567 | Let's Play |
| 8. | Kevduit | I FORCED myself to play Mass Effect Andromeda | 249,092 | |
| 9. | TetraNinja | Mass Effect Andromeda Walkthrough Part 3 - TEMPEST RISING (PC Ultra Let's Play Commentary) | 229,226 | Let's Play |
| 10. | FRIENDLY Ai | Mass Effect 4 Anouncement During 2013 VGAs | 216,846 | |
| 11. | TetraNinja | Mass Effect Andromeda Walkthrough Part 8 - VAULT (PC Ultra Let's Play Commentary) | 216,068 | Let's Play |
| 12. | TeyTheGod | Bioware... wtf is this. | 205,331 | |
| 13. | TetraNinja | Mass Effect Andromeda Walkthrough Part 5 - EOS (PC Ultra Let's Play Commentary) | 204,873 | Let's Play |
| 14. | VGS - Video Game Sophistry | Mass Effect Andromeda: The Ryders KNOW how to Flirt (PART 1) | 199,779 | Guide |
| 15. | TetraNinja | Mass Effect Andromeda Walkthrough Part 4 - Sabotage (PC Ultra Let's Play Commentary) | 197,862 | Let's Play |
| 16. | TetraNinja | Mass Effect Andromeda Walkthrough Part 6 - NOMAD (PC Ultra Let's Play Commentary) | 194,870 | Let's Play |
| 17. | FRIENDLY Ai | Mass Effect 4 Info Leaked: Story, New Alien Race, Planets, Love | 189,866 | |
| 18. | TetraNinja | Mass Effect Andromeda Walkthrough Part 9 - OUTPOST (PC Ultra Let's Play Commentary) | 171,820 | Let's Play |
| 19. | TetraNinja | Mass Effect Andromeda Walkthrough Part 7 - DRACK (PC Ultra Let's Play Commentary) | 166,729 | Let's Play |
| 20. | gamermd83 | Mass Effect Andromeda - Multiplayer NEW Footage & Info (EXCLUSIVE) | 162,763 | |
| 21. | TetraNinja | Mass Effect Andromeda Walkthrough Part 10 - Team Meeting (PC Ultra Let's Play Commentary) | 142,679 | Let's Play |
| 22. | Егор Клёнов | Сюжет Mass Effect: Andromeda без мишуры | 139,441 | |
| 23. | Егор Клёнов | Обзор Mass Effect: Andromeda, или Плохая мина при хорошей игре | 133,185 | |
| 24. | VGS - Video Game Sophistry | Mass Effect Andromeda: Liam and Ryder Romance Scene | 129,643 | |
| 25. | VGS - Video Game Sophistry | Mass Effect Andromeda: Complete Jaal Romance | 129,482 | |
| 26. | gamermd83 | Mass Effect Andromeda: Creating A Hero (Gameinformer News) | 127,432 | |
| 27. | TetraNinja | Mass Effect Andromeda Walkthrough Part 14 - Pants Optional Party (PC Ultra Let's Play Commentary) | 127,088 | Let's Play |
| 28. | TetraNinja | Mass Effect Andromeda Walkthrough Part 13 - ANGARA (PC Ultra Let's Play Commentary) | 124,411 | Let's Play |
| 29. | TetraNinja | Mass Effect Andromeda Walkthrough Part 15 - SPECTRE (PC Ultra Let's Play Commentary) | 122,446 | Let's Play |
| 30. | TetraNinja | Mass Effect Andromeda Walkthrough Part 11 - Suvi's Faith (PC Ultra Let's Play Commentary) | 120,033 | Let's Play |
| 31. | TetraNinja | Mass Effect Andromeda Walkthrough Part 12 - CRYO PODS (PC Ultra Let's Play Commentary) | 119,480 | Let's Play |
| 32. | TetraNinja | Mass Effect Andromeda Walkthrough Part 19 - PLANET BOSS REMNANT ARCHITECT (PC Ultra Let's Play) | 115,112 | Let's Play |
| 33. | YOURBOYRECON | Mass Effect Andromeda - GET 10 MILLION CREDITS FAST! (MONEY CHEAT/EXPLOIT!) | 113,097 | |
| 34. | TetraNinja | Mass Effect Andromeda Walkthrough Part 18 - A Dying Planet (PC Ultra Let's Play Commentary) | 108,475 | Let's Play |
| 35. | ChristopherOdd | Mass Effect Andromeda EP 1 - A NEW FRONTIER - Let's Play Gameplay Part 1 | 106,901 | Let's Play |
| 36. | TetraNinja | Mass Effect Andromeda Walkthrough Part 16 - TRAIL OF HOPE (PC Ultra Let's Play Commentary) | 105,625 | Let's Play |
| 37. | VGS - Video Game Sophistry | Mass Effect Andromeda: Saren's Protege - Avitus Rix | 101,800 | |
| 38. | TetraNinja | Mass Effect Andromeda Walkthrough Part 22 - PLANET VOELD (PC Ultra Let's Play Commentary) | 95,800 | Let's Play |
| 39. | TetraNinja | Mass Effect Andromeda Walkthrough Part 17 - AC Quest (PC Ultra Let's Play Commentary) | 95,073 | Let's Play |
| 40. | YOURBOYRECON | Best Assault Rifle & Augmentations - Mass Effect Andromeda | 93,657 | |
| 41. | Gaming Ambience | Mass Effect: Andromeda - Main Menu Theme (1 Hour of Music) | 92,618 | |
| 42. | JoshuaPare | That Sound Every Call of Duty Zombie Player Fears | 90,403 | |
| 43. | VGS - Video Game Sophistry | Mass Effect Andromeda: Liam Romance - Sex and Soccer | 90,331 | |
| 44. | gamermd83 | Mass Effect Andromeda Trailer Reaction! (E3 2015) | 85,985 | Preview |
| 45. | TetraNinja | Mass Effect Andromeda Walkthrough Part 20 - KETT BASE (PC Ultra Let's Play Commentary) | 85,059 | Let's Play |
| 46. | VGS - Video Game Sophistry | Mass Effect Andromeda: Jaal and Liam, Shirtless Diplomacy | 84,063 | |
| 47. | DanQ8000 | Mass Effect: Andromeda - Let's Play - Part 1 - "Character Creation" | DanQ8000 | 82,813 | Let's Play |
| 48. | TetraNinja | Mass Effect Andromeda Walkthrough Part 21 - Asari Ark Lead (PC Ultra Let's Play Commentary) | 81,350 | Let's Play |
| 49. | TetraNinja | Mass Effect Andromeda Walkthrough Part 72 - ENDING + FINAL BOSS (PC Ultra Let's Play Commentary) | 81,227 | Let's Play |
| 50. | TetraNinja | Mass Effect Andromeda Walkthrough Part 23 - ICE (PC Ultra Let's Play Commentary) | 80,559 | Let's Play |
| 51. | The Triple S League | Mass Effect Andromeda: How to Decrypt Remnant Technology Vaults with Puzzle Solving | 79,189 | Guide |
| 52. | HannaH's Over Invested | Non-Gamer Watches #84 MASS EFFECT | Mass Effect 1, Mass Effect 2, Andromeda & the New Mass Effect | 78,484 | Preview |
| 53. | VGS - Video Game Sophistry | Mass Effect Andromeda: Female Ryder - Part 1 "Prologue" | 75,914 | Vlog |
| 54. | VGS - Video Game Sophistry | Mass Effect: Andromeda Review - An Existential Disappointment | 75,411 | Review |
| 55. | VGS - Video Game Sophistry | Mass Effect Andromeda: Female Ryder - Part 6 "New Friends" | 75,408 | |
| 56. | VGS - Video Game Sophistry | Mass Effect Andromeda: Peebee No-Strings SEX SCENE (All Options) | 73,024 | |
| 57. | YOURBOYRECON | Mass Effect Andromeda - How to Get RARE WEAPONS & MONEY EARLY! - Unlimited Credits! | 72,472 | Guide |
| 58. | TetraNinja | Mass Effect Andromeda Walkthrough Part 26 - Kett Base Attack (PC Ultra Let's Play Commentary) | 70,895 | Let's Play |
| 59. | TetraNinja | Mass Effect Andromeda Walkthrough Part 24 - Flight Recorder (PC Ultra Let's Play Commentary) | 70,447 | Let's Play |
| 60. | smudboy | Boycott ME4: Top 5 Reasons | 69,384 | |
| 61. | Hrag Farra | Mass Effect Andromeda - Full (Soundtrack OST) | 69,006 | |
| 62. | gamermd83 | Mass Effect Andromeda: Building Relationships (GameInformer News) | 66,979 | |
| 63. | TetraNinja | Mass Effect Andromeda Walkthrough Part 25 - Voeld Map (PC Ultra Let's Play Commentary) | 65,234 | Let's Play |
| 64. | TetraNinja | Mass Effect Andromeda Walkthrough Part 28 - LADY AI (PC Ultra Let's Play Commentary) | 64,812 | Let's Play |
| 65. | YOURBOYRECON | RIDICULOUSLY OP SENTINEL BUILD (Most DPS) Mass Effect Andromeda | 61,667 | Guide |
| 66. | gamermd83 | Mass Effect Andromeda Special: Leaving Andromeda (PART 1) | 61,310 | |
| 67. | Егор Клёнов | 5 проблем Mass Effect: Andromeda (кроме лицевой анимации) | 60,687 | |
| 68. | TetraNinja | Mass Effect Andromeda Walkthrough Part 30 - VOELD VAULT (PC Ultra Let's Play Commentary) | 60,201 | Let's Play |
| 69. | gamermd83 | Mass Effect Andromeda - Being An Infiltrator | 59,158 | |
| 70. | TetraNinja | Mass Effect Andromeda Walkthrough Part 32 - MOSHAE & CARDINAL (PC Ultra Let's Play Commentary) | 58,859 | Let's Play |
| 71. | VGS - Video Game Sophistry | Mass Effect Andromeda: Transgender Character - Hainly Abrams | 58,526 | |
| 72. | TetraNinja | Mass Effect Andromeda Walkthrough Part 73 - EPILOGUE & ROMANCE + MOVIE NIGHT! | 58,473 | Walkthrough |
| 73. | TetraNinja | Mass Effect Andromeda Walkthrough Part 38 - KADARA PORT (PC Ultra Let's Play Commentary) | 58,456 | Let's Play |
| 74. | TetraNinja | Mass Effect Andromeda Walkthrough Part 43 - ELAADAN (PC Ultra Let's Play Commentary) | 57,618 | Let's Play |
| 75. | VGS - Video Game Sophistry | Mass Effect Andromeda: Peebee No-Strings FEMALE SEX SCENE (All Options) | 56,925 | |
| 76. | HappyConsoleGamer | MASS EFFECT ANDROMEDA (First Thoughts) - Happy Console Gamer | 56,700 | |
| 77. | TetraNinja | Mass Effect Andromeda Walkthrough Part 31 - EXALTED (PC Ultra Let's Play Commentary) | 55,902 | Let's Play |
| 78. | VGS - Video Game Sophistry | Mass Effect Andromeda: Meeting Peebee | 55,505 | |
| 79. | SomeOrdinaryGamers | YouTube's New Age Restrictions! | 55,364 | |
| 80. | TetraNinja | Mass Effect Andromeda Walkthrough Part 35 - AYA (PC Ultra Let's Play Commentary) | 55,331 | Let's Play |
| 81. | TetraNinja | Mass Effect Andromeda Walkthrough Part 29 - VOELD MONOLITHS (PC Ultra Let's Play Commentary) | 54,582 | Let's Play |
| 82. | VGS - Video Game Sophistry | Mass Effect Andromeda: Meet Bain Massani, the son of Zaeed Massani | 54,464 | |
| 83. | TetraNinja | Mass Effect Andromeda Walkthrough Part 42 - REMNANT TILLER (PC Ultra Let's Play Commentary) | 54,134 | Let's Play |
| 84. | TetraNinja | Mass Effect Andromeda Walkthrough Part 33 - MAMA RYDER (PC Ultra Let's Play Commentary) | 53,563 | Let's Play |
| 85. | BestAtNothing | CLOWN EFFECT ANDROMEDA | 53,000 | |
| 86. | TetraNinja | Mass Effect Andromeda Walkthrough Part 39 - CORA LOYALTY MISSION (PC Ultra Let's Play Commentary) | 52,892 | Let's Play |
| 87. | YOURBOYRECON | UNLIMITED EXPERIENCE POINTS GLITCH! - Mass Effect Andromeda (100K in 5 Mins) LEVEL UP FAST! | 52,633 | |
| 88. | TetraNinja | Mass Effect Andromeda Walkthrough Part 37 - LIAM LOYALTY MISSION (PC Ultra Let's Play Commentary) | 52,462 | Let's Play |
| 89. | Rubhen925 | Mass Effect Andromeda - Crytographer Trophy/Achievement Guide (All 20 Remnant Puzzles) | 52,334 | Guide |
| 90. | TetraNinja | Mass Effect Andromeda Walkthrough Part 36 - AYA VAULT (PC Ultra Let's Play Commentary) | 52,325 | Let's Play |
| 91. | TetraNinja | Mass Effect Andromeda Walkthrough Part 46 - ELAADAN VAULT (PC Ultra Let's Play Commentary) | 52,252 | Let's Play |
| 92. | VGS - Video Game Sophistry | Mass Effect Andromeda: Voeld Boss Fight - Architect | 51,401 | |
| 93. | ChristopherOdd | Mass Effect Andromeda EP 2 - SR RYDER - Let's Play Gameplay Part 2 | 50,870 | Let's Play |
| 94. | TetraNinja | Mass Effect Andromeda Walkthrough Part 34 - Murder on Nexus (PC Ultra Let's Play Commentary) | 50,257 | Let's Play |
| 95. | Liana K | I tackle the Mass Effect Andromeda Clusterf*ck | 49,925 | |
| 96. | gamermd83 | REACTION Mass Effect Andromeda EA Play Video | 49,486 | |
| 97. | VGS - Video Game Sophistry | Mass Effect Andromeda: EOS Side Missions - The Secret Project | 49,465 | |
| 98. | TetraNinja | Mass Effect Andromeda Walkthrough Part 45 - REMNANT DRIVE CORE (PC Ultra Let's Play Commentary) | 49,357 | Let's Play |
| 99. | Wolfian | CARRY GOLD EASY - Asari Adept (OP?) Beginner's Build Guide - Mass Effect Andromeda Multiplayer | 49,249 | Guide |
| 100. | rizzler | Gaming News: PS4 Neo = PS4 Pro & PS4 Slim Reveal, Release Dates and Prices; Mass Effect Andromeda | 49,161 | |
