| 1. |  Rooster Teeth | 2,883,122 | Let's Play - MLB 2K12 - With Geoff and Gav | Rooster Teeth | 30:00 |
| 2. | Poofesure | 374,517 | mlb 2k12 wii raging and funny moments | 18:45 |
| 3. | Sports Gaming Universe | 241,759 | MLB 2K12 My Player: Kent Hrbek EP 4 | 5:38 |
| 4. | IGN | 189,123 | MLB 2K12 - Video Review | 3:01 |
| 5. | FaustoSportsReacts | 145,052 | MLB 2K12 WBC MOD 2K17 Republica Dominicana VS USA | 29:26 |
| 6. | dunbarsnackbar | 69,219 | MLB 2K12: Timmy Timmons: Episode 12 - My Player | 12:34 |
| 7. | TeemingTubbyEmu | 28,355 | MLB 2K12 - My Player w/ Drew McTubbs - Episode 3 | 5:29 |
| 8. | AlphaOmegaSin | 23,144 | MLB 2K12 One Million Dollar Cheater Given the OK by 2K Games | 7:46 |
| 9. | SportsGamerShow | 16,077 | MLB 2K12 - Perfect Game Challenge Tutorial | 6:04 |
| 10. | MrHurriicane | 15,315 | MLB 2k12 Demo Gameplay & Analysis - Texas Rangers vs St. Louis Cardinals | 8:14 |
| 11. | AnEternalEnigma | 8,522 | THIS GAME SUCKS: MLB 2K12 Demo | 10:00 |
| 12. | baseballlover312 | 4,509 | MLB 2K12 - Yankees Franchise - Episode 23 | 32:08 |
| 13. | The Escapist | 1,714 | MLB 2K12 Review | 3:30 |
| 14. | igcompany | 742 | 2012 World Series - San Francisco Giants vs. Detroit Tigers MLB 2K12 | 10:21 |
| 15. | SinWithVengeance | 581 | MLB 2K12 My Player- Real MLB Playoff Picture | 13:12 |
| 16. | Deiradinn | 568 | MLB2K12 - Cubs Vs Cards "Full Game" | 42:00 |
| 17. | ajmarkle | 503 | CALLED UP TO THE MLB LEVEL! | MLB 2K12 | My Career #12 | 12:15 |
| 18. | Game Informer | 492 | MLB 2K12 Gameplay Trailer | 7:53 |
| 19. | Nighterlev | 293 | Xenia D3D12 - MLB 2K12 | 1:24 |
| 20. | AvalancheFan133 | 277 | Let's Play MLB 2K12 With xSixXAssasinX | 31:27 |
| 21. | Quiet Breezie🌈🚔 | 256 | 430-13 MLB 2K12 franchise The Kid with the Washington Nats | 0:00 |
| 22. | Mikefromla1 | 169 | Bart Simpson My Player MLB 2K12 Ep 12 | 11:52 |
| 23. | Speed Hunter (Jesse Underhill) | 17 | MLB 2K12 lets play | 40:54 |
