| 2025-01-02 |  Squander | 514 | Quake 4 - Part 2: We Need Bigger Weapons | 0:00 |
| 2024-07-04 | doc reaper | 285 | Quake 4 (probably end up as a grabbag) | 2:53:08 |
| 2024-03-29 | ariallla | 233 | Chat silences me while I sing?! ~ playing Quake 4 | 0:30 |
| 2024-03-10 | HJ's Corner | 5,600 | Quake 4 (Gametrailers Review) (PC/Xbox 360) | 5:40 |
| 2024-03-01 | AmityB2002 | 678 | [FULL VOD] Such a great game! - Quake 4 FINALE | 2:38:47 |
| 2024-01-29 | Onthim Gaming HDR | 4,360 | Crazy good game Quake 4 #gaming | 0:15 |
| 2023-07-20 | Jyegame | 981 | THE START | Quake 4 | 5:01:13 |
| 2023-02-15 | Sacko | 7,020 | Quake 4: An Underrated Gem | 12:09 |
| 2022-12-20 | MadLadCarbz | 151 | Quake 4 Final | 37:41 |
| 2022-12-16 | MicksysPCGaming | 89 | First 30 Minutes - Quake 4 - 4K - Intel I9 13900K - Gigabyte 4090 Gaming OC | 26:36 |
| 2022-11-04 | Lilith Thelema Ch. Infinite Live | 1,100 | Tower connections | 33:26 |
| 2022-07-05 | 🎮 I give it 30 minutes! 🎮 | 215 | I give "Quake 4" 30 minutes! | 30:01 |
| 2022-06-13 | PLAYER PRIME | 735 | QUAKE 4 - Juego Completo en Español-1080p!!! | 3:42:49 |
| 2022-05-29 | FP Media | 17,900 | REVISITING QUAKE 4 | 5:43 |
| 2021-09-15 | Gamings Greatest | 1,920 | [9] Quake 4 | Wysteria Gaming Classics Series | Episode 9 | 2:41 |
| 2021-07-05 | Crimson Skull | 621 | Quake 4 General Difficulty Part 3 | 52:52 |
| 2020-08-04 | DylboFPS | 175 | QUAKE 4 in 2020 | Part 1 | 1:39:27 |
| 2020-07-04 | MrAnderson | 128 | Quake 4 1080p 60 FPS PC | 59:09 |
| 2020-05-17 | PickledDonutLord | 3,030 | Xenia 1.0.2163-master | Quake 4 [XBOX360 EMULATION] | 3:12 |
| 2020-01-18 | UltrawidePCGaming | 2,320 | Quake 4 | Ultrawide 3440x1440 | With Hi-Def Mod & FOV Fix | Gameplay | 11:53 |
| 2020-01-14 | The Destroia Plays Games | 128 | Quake 4: Highlight 3: Nice dodge, Gunner! | 0:00 |
| 2019-09-22 | Playthrough Emporium | 6,640 | Quake 4 - Full Game Playthrough | Longplay - PC - HD | 4:06:23 |
| 2019-07-11 | HacknSlashMB | 11,600 | Quake 4 [PC] - All Bosses (With Cutscenes) [HD] | 25:50 |
| 2018-10-22 | T J | 11 | ecent v zlr ABC goodgame WGT 2007 Quake 4 | 0:58 |
| 2017-03-10 | TheZombieKiller | 531 | Quake 4 - Full Body Awareness | 2:17 |
| 2015-04-11 | GmanLives | 801,000 | Quake 4 PC Game Review | 7:38 |
| 2015-02-06 | Danger Dolan | 987,000 | 15 Video Games That Ruined Their Franchise | 9:14 |
| 2014-12-10 | Andy Keunen Plays | 591 | Quake 4 - A Playthrough, Part 29 | 7:45 |
| 2013-12-30 | Drakaza | 2,530 | Shadow replay Quake 4 episode 06 | 1:09:41 |
| 2011-08-27 | MrOptimusheath | 2,950 | QUAKE 4 - machine gun | 2:48 |
| 2006-09-04 | Danial Carroll | 230 | Quake 4 Intro | 3:07 |
