Kisspeptin
3Kisspeptins (including kisspeptin-54 (KP-54), formerly known as metastin) are proteins encoded by the KISS1 gene in humans. Kisspeptins are ligands of the G-protein coupled receptor, GPR54. Kiss1 was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty, the extent of which is an area of ongoing research. Gonadotropin-releasing hormone is released from the hypothalamus to act on the anterior pituitary triggering the release of luteinizing hormone (LH), and follicle stimulating hormone (FSH). These gonadotropic hormones lead to sexual maturation and gametogenesis. Disrupting GPR54 signaling can cause hypogonadotrophic hypogonadism in rodents and humans. The Kiss1 gene is located on chromosome 1. It is transcribed in the brain, adrenal gland, and pancreas.
Source: https://en.wikipedia.org/wiki/Kisspeptin
Created with WikipediaReaderReborn (c) WikipediaReader
Other Videos By WikiReader
| 2022-01-26 | Computational epistemology |
| 2022-01-26 | Brush (electric) |
| 2022-01-26 | Neil Freeman (English footballer) |
| 2022-01-26 | After All These Years (Instrumental) |
| 2022-01-26 | Gifu Shotoku Gakuen University |
| 2022-01-26 | Neil Garratt |
| 2022-01-26 | Fred Taylor (American football) |
| 2022-01-26 | Unstoppable (Sia song) |
| 2022-01-26 | Undzer emes |
| 2022-01-26 | Ibram Lassaw |
| 2022-01-26 | Kisspeptin |
| 2022-01-26 | Józefów, Gmina Gorzków |
| 2022-01-26 | 2020 Kerala floods |
| 2022-01-26 | Neodiplocampta |
| 2022-01-26 | 1983 PBA All-Filipino Conference Finals |
| 2022-01-26 | Helidon Spa, Queensland |
| 2022-01-26 | Pat Lee |
| 2022-01-26 | Kerrick Jackson |
| 2022-01-26 | Challenger Columbia Stadium |
| 2022-01-26 | Petar Malinov |
| 2022-01-26 | Viscera (God Module album) |