The Lost Mind of Dr. Brain is the third installment of the original Dr. Brain series, which were educational games published by Sierra On-Line. An educational game for children where different puzzles are needed to be done to put Dr. Brains brain back together again.
The Lost Mind of Dr. Brain features science-related puzzles similar to the first two games in the series. Previous installments featured a large, semi-free-roaming environment. However, The Lost Mind of Dr. Brain restricts the player to a single area (Dr. Brain's laboratory), with puzzles accessed from a central 'map' screen. Dr. Brain's niece, Elaina (voiced by Kayce Glasse) replaces Dr. Brain as host and serves as a guide to Dr. Brain's mental pathways. While the previous games' puzzles ranged across a variety of disciplines (both Castle and Island contained memory and word puzzles, as well as puzzles related to art and the sciences), The Lost Mind of Dr. Brain focuses solely on the human brain, with puzzles related to spatial orientation, memorization, and symbolic association.
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