Top 100 The Binding of Isaac Videos With The Longest Duration by ShuffleFM
| Video Title | Duration | Category | Game | |
|---|---|---|---|---|
| 1. | Pokemon meets Binding of Isaac - The Funniest Game This Year | Restless Soul (Sponsored) | 2:21:13 | The Binding of Isaac | |
| 2. | Let's Play (One Shot Series): Ziggurat | 23:41 | Let's Play | The Binding of Isaac |