| 1. | Bisnap Plays Isaac: Rebirth Episode 1 - Fresh | 151,920 | Let's Play | The Binding of Isaac: Rebirth
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| 2. | Bisnap Plays Isaac: Rebirth Episode 3 - Trouble | 91,287 | Let's Play | The Binding of Isaac: Rebirth
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| 3. | Bisnap Plays Isaac: Rebirth Episode 2 - Expedition | 89,461 | Let's Play | The Binding of Isaac: Rebirth
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| 4. | Bisnap Plays Isaac: Afterbirth Episode 1 - Love | 76,535 | Let's Play | The Binding of Isaac: Rebirth
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| 5. | Bisnap Plays Isaac: Rebirth Episode 5 - Limitation | 73,256 | Let's Play | The Binding of Isaac: Rebirth
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| 6. | Bisnap Plays Isaac: Rebirth Episode 4 - Anti-plan | 71,121 | Let's Play | The Binding of Isaac: Rebirth
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| 7. | Bisnap Plays Isaac: Rebirth Episode 7 - Chaos | 65,164 | Let's Play | The Binding of Isaac: Rebirth
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| 8. | Bisnap Plays Isaac: Rebirth Episode 6 - Cubic | 62,812 | Let's Play | The Binding of Isaac: Rebirth
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| 9. | Bisnap Plays Isaac: Rebirth Episode 8 - Remember | 60,813 | Let's Play | The Binding of Isaac: Rebirth
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| 10. | Bisnap Plays Isaac: Rebirth Episode 9 - Tsunami | 60,560 | Let's Play | The Binding of Isaac: Rebirth
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| 11. | Bisnap Plays Isaac: Rebirth Episode 13 - Squish | 55,269 | Let's Play | The Binding of Isaac: Rebirth
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| 12. | Bisnap Plays Isaac: Rebirth Episode 11 - Redo | 55,191 | Let's Play | The Binding of Isaac: Rebirth
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| 13. | Bisnap Plays Isaac: Rebirth Episode 10 - Specialize | 54,764 | Let's Play | The Binding of Isaac: Rebirth
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| 14. | Bisnap Plays Isaac: Rebirth Episode 66 - Breaking #1 | 54,241 | Let's Play | The Binding of Isaac: Rebirth
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| 15. | Bisnap Plays Isaac: Rebirth Episode 15 - Admittance | 52,744 | Let's Play | The Binding of Isaac: Rebirth
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| 16. | Bisnap Plays Isaac: Rebirth Episode 12 - Big | 51,197 | Let's Play | The Binding of Isaac: Rebirth
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| 17. | Bisnap Plays Isaac: Afterbirth Episode 8 - Quantum [Breaking] | 48,993 | Let's Play | The Binding of Isaac: Rebirth
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| 18. | Bisnap Plays Isaac: Rebirth Episode 16 - Intent | 48,590 | Let's Play | The Binding of Isaac: Rebirth
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| 19. | Bisnap Plays Isaac: Rebirth Episode 22 - Mega | 47,533 | Let's Play | The Binding of Isaac: Rebirth
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| 20. | Bisnap Plays Isaac: Rebirth Episode 14 - Accomplishment | 47,466 | Let's Play | The Binding of Isaac: Rebirth
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| 21. | Bisnap Plays Isaac: Rebirth Episode 19 - Kick | 46,886 | Let's Play | The Binding of Isaac: Rebirth
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| 22. | Bisnap Plays Isaac: Rebirth Episode 20 - Sail | 46,486 | Let's Play | The Binding of Isaac: Rebirth
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| 23. | Bisnap Streams Isaac: Afterbirth - Part 100 [Breaking] | 45,478 | | The Binding of Isaac: Rebirth
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| 24. | Bisnap Streams Isaac: Afterbirth+ - Part 1 | 44,781 | | The Binding of Isaac: Rebirth
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| 25. | Bisnap Streams Isaac: Rebirth - Part 1 | 44,747 | Let's Play | The Binding of Isaac: Rebirth
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| 26. | Bisnap Plays Isaac: Rebirth Episode 17 - Steady | 44,414 | Let's Play | The Binding of Isaac: Rebirth
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| 27. | Bisnap Plays Isaac: Rebirth Episode 21 - Whim | 44,365 | Let's Play | The Binding of Isaac: Rebirth
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| 28. | Bisnap Plays Isaac: Afterbirth Episode 2 - Form | 43,675 | Let's Play | The Binding of Isaac: Rebirth
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| 29. | Bisnap Plays Isaac: Rebirth Episode 67 - Breaking #2 | 43,280 | Let's Play | The Binding of Isaac: Rebirth
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| 30. | Bisnap Plays Isaac: Afterbirth Episode 4 - Greedy | 42,814 | Let's Play | The Binding of Isaac: Rebirth
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| 31. | Bisnap Plays Isaac: Rebirth Episode 23 - Roll | 41,048 | Let's Play | The Binding of Isaac: Rebirth
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| 32. | Bisnap Plays Isaac: Rebirth Episode 18 - Found | 40,637 | Let's Play | The Binding of Isaac: Rebirth
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| 33. | Bisnap Plays Isaac: Afterbirth Episode 3 - Lilith | 39,748 | Let's Play | The Binding of Isaac: Rebirth
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| 34. | Bisnap Plays Isaac: Rebirth Episode 28 - Fore | 39,504 | Let's Play | The Binding of Isaac: Rebirth
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| 35. | Bisnap Plays Isaac: Rebirth Episode 24 - Reverse | 39,441 | Let's Play | The Binding of Isaac: Rebirth
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| 36. | Bisnap Plays Isaac: Rebirth Episode 25 - Axis | 37,842 | Let's Play | The Binding of Isaac: Rebirth
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| 37. | Bisnap Plays Isaac: Afterbirth+ Episode 1 - Prospect | 37,807 | Let's Play | The Binding of Isaac: Rebirth
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| 38. | Bisnap Plays Isaac: Rebirth Episode 27 - Intended | 37,741 | Let's Play | The Binding of Isaac: Rebirth
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| 39. | Bisnap Plays Isaac: Rebirth Episode 32 - Uptake | 37,164 | Let's Play | The Binding of Isaac: Rebirth
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| 40. | Bisnap Plays Isaac: Rebirth Episode 89 - Breaking #3 | 36,487 | Let's Play | The Binding of Isaac: Rebirth
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| 41. | Bisnap Streams Isaac: Afterbirth - Part 1 | 35,815 | | The Binding of Isaac: Rebirth
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| 42. | Bisnap Plays Isaac: Rebirth Episode 29 - Marathon | 35,451 | Let's Play | The Binding of Isaac: Rebirth
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| 43. | Bisnap Plays Isaac: Rebirth Episode 31 - Tumble | 35,207 | Let's Play | The Binding of Isaac: Rebirth
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| 44. | Bisnap Plays Isaac: Rebirth Episode 26 - Concept | 34,875 | Let's Play | The Binding of Isaac: Rebirth
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| 45. | Bisnap Plays Isaac: Afterbirth Episode 5 - Preside | 34,794 | Let's Play | The Binding of Isaac: Rebirth
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| 46. | Bisnap Streams Isaac: Rebirth - Part 111 [Breaking] | 34,776 | Let's Play | The Binding of Isaac: Rebirth
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| 47. | Bisnap Plays Isaac: Rebirth Episode 35 - Unplanned | 34,425 | Let's Play | The Binding of Isaac: Rebirth
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| 48. | Bisnap Streams Isaac: Afterbirth - Part 23 [Breaking] | 34,188 | | The Binding of Isaac: Rebirth
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| 49. | Bisnap Streams Isaac: Afterbirth+ - Part 4 [Breaking] | 33,857 | | The Binding of Isaac: Rebirth
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| 50. | Bisnap Streams Isaac: Afterbirth - Part 9 [Breaking] | 33,507 | | The Binding of Isaac: Rebirth
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| 51. | Bisnap Plays Isaac: Rebirth Episode 30 - Moment | 32,538 | Let's Play | The Binding of Isaac: Rebirth
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| 52. | Bisnap Plays Isaac: Rebirth Episode 91 - The Lost (Part 1) | 31,906 | Let's Play | The Binding of Isaac: Rebirth
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| 53. | Bisnap Plays Isaac: Rebirth Episode 33 - Traction | 31,352 | Let's Play | The Binding of Isaac: Rebirth
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| 54. | Bisnap Streams Isaac: Rebirth - Part 122 [Breaking] | 31,297 | Let's Play | The Binding of Isaac: Rebirth
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| 55. | Bisnap Plays Isaac: Rebirth Episode 37 - Clarity | 30,892 | Let's Play | The Binding of Isaac: Rebirth
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| 56. | Bisnap Plays Isaac: Rebirth Episode 41 - Hole | 30,823 | Let's Play | The Binding of Isaac: Rebirth
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| 57. | Bisnap Plays Isaac: Rebirth Episode 36 - Witch | 30,809 | Let's Play | The Binding of Isaac: Rebirth
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| 58. | Bisnap Streams Isaac: Afterbirth+ - Part 141 [Breaking] | 30,627 | | The Binding of Isaac: Rebirth
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| 59. | Bisnap Plays Isaac: Afterbirth Episode 6 - Troll | 30,594 | Let's Play | The Binding of Isaac: Rebirth
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| 60. | Bisnap Plays Isaac: Rebirth Episode 34 - Through | 30,515 | Let's Play | The Binding of Isaac: Rebirth
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| 61. | Bisnap Plays Isaac: Afterbirth Episode 9 - Enormity | 29,544 | Let's Play | The Binding of Isaac: Rebirth
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| 62. | Bisnap Plays Isaac: Rebirth Episode 42 - Backfire | 29,409 | Let's Play | The Binding of Isaac: Rebirth
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| 63. | Bisnap Plays Isaac: Rebirth Episode 38 - Diet | 29,176 | Let's Play | The Binding of Isaac: Rebirth
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| 64. | Bisnap Plays Isaac: Rebirth Episode 39 - Revision | 28,815 | Let's Play | The Binding of Isaac: Rebirth
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| 65. | Bisnap Plays Isaac: Rebirth Episode 43 - Blot | 28,595 | Let's Play | The Binding of Isaac: Rebirth
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| 66. | Bisnap Streams Isaac: Rebirth - Part 55 [Breaking] | 28,594 | Let's Play | The Binding of Isaac: Rebirth
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| 67. | Bisnap Plays Isaac: Afterbirth Episode 10 - Cog | 28,532 | Let's Play | The Binding of Isaac: Rebirth
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| 68. | Bisnap Plays Isaac: Rebirth Episode 49 - Mould | 28,458 | Let's Play | The Binding of Isaac: Rebirth
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| 69. | Bisnap Plays Isaac: Rebirth Episode 40 - Transparent | 28,195 | Let's Play | The Binding of Isaac: Rebirth
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| 70. | Bisnap Plays Isaac: Rebirth Episode 50 - Patch | 28,153 | Let's Play | The Binding of Isaac: Rebirth
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| 71. | Bisnap Plays Isaac: Afterbirth Episode 238 - Baby [Breaking] | 27,891 | Let's Play | The Binding of Isaac: Rebirth
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| 72. | Bisnap Plays Isaac: Rebirth Episode 45 - Cult | 27,417 | Let's Play | The Binding of Isaac: Rebirth
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| 73. | Bisnap Plays Isaac: Rebirth Episode 48 - Head | 27,105 | Let's Play | The Binding of Isaac: Rebirth
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| 74. | Bisnap Plays Isaac: Rebirth Episode 46 - Allocation | 26,802 | Let's Play | The Binding of Isaac: Rebirth
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| 75. | Bisnap Plays Isaac: Rebirth Episode 44 - Contained | 26,559 | Let's Play | The Binding of Isaac: Rebirth
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| 76. | Bisnap Plays Isaac: Afterbirth Episode 7 - Millennium | 26,552 | Let's Play | The Binding of Isaac: Rebirth
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| 77. | Bisnap Plays Isaac Community Remix - Part 4 | 26,323 | Let's Play | The Binding of Isaac: Rebirth
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| 78. | Bisnap Streams Isaac: Repentance - Part 1 | 26,248 | | The Binding of Isaac: Rebirth
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| 79. | Bisnap Plays Isaac: Rebirth Episode 176 - Breaking #5 | 25,717 | Let's Play | The Binding of Isaac: Rebirth
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| 80. | Bisnap Plays Isaac: Afterbirth Episode 11 - Duplicate | 25,703 | Let's Play | The Binding of Isaac: Rebirth
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| 81. | Bisnap Plays Isaac: Rebirth Episode 56 - Can | 25,629 | Let's Play | The Binding of Isaac: Rebirth
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| 82. | Bisnap Plays Isaac: Rebirth Episode 57 - Matter | 25,518 | Let's Play | The Binding of Isaac: Rebirth
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| 83. | Bisnap Streams Isaac: Rebirth - Part 67 [Breaking] | 25,129 | Let's Play | The Binding of Isaac: Rebirth
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| 84. | Bisnap Plays Isaac: Rebirth Episode 69 - Persistence | 25,039 | Let's Play | The Binding of Isaac: Rebirth
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| 85. | Bisnap Plays Isaac: Rebirth Episode 58 - Machine | 25,009 | Let's Play | The Binding of Isaac: Rebirth
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| 86. | Bisnap Plays Isaac: Afterbirth Episode 53 - Keep [Breaking] | 24,938 | Let's Play | The Binding of Isaac: Rebirth
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| 87. | Bisnap Plays Isaac: Rebirth Episode 55 - Glean | 24,620 | Let's Play | The Binding of Isaac: Rebirth
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| 88. | Bisnap Plays Isaac: Rebirth Episode 47 - Preparation | 24,601 | Let's Play | The Binding of Isaac: Rebirth
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| 89. | Bisnap Streams Isaac: Afterbirth - Part 15 [Breaking] | 24,501 | | The Binding of Isaac: Rebirth
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| 90. | Bisnap Plays Isaac: Afterbirth+ Episode 2 - Relive | 24,487 | Let's Play | The Binding of Isaac: Rebirth
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| 91. | Bisnap Plays Isaac: Rebirth Episode 52 - Touch | 24,332 | Let's Play | The Binding of Isaac: Rebirth
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| 92. | Bisnap Streams Isaac: Rebirth - Part 145 [Breaking] | 24,084 | Let's Play | The Binding of Isaac: Rebirth
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| 93. | Bisnap Streams Isaac: Rebirth - Part 2 | 24,048 | Let's Play | The Binding of Isaac: Rebirth
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| 94. | Bisnap Streams Isaac: Afterbirth+ - Part 320 [Breaking] | 23,978 | | The Binding of Isaac: Rebirth
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| 95. | Bisnap Streams Isaac: Afterbirth+ - Part 2 | 23,796 | | The Binding of Isaac: Rebirth
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| 96. | Early Rebirth Impressions | 23,743 | Let's Play | The Binding of Isaac: Rebirth
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| 97. | Bisnap Plays Isaac: Rebirth Episode 63 - Piece | 23,704 | Let's Play | The Binding of Isaac: Rebirth
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| 98. | Bisnap Plays Isaac: Rebirth Episode 51 - Swap | 23,568 | Let's Play | The Binding of Isaac: Rebirth
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| 99. | Bisnap Plays Isaac: Rebirth Episode 68 - Crucial | 23,495 | Let's Play | The Binding of Isaac: Rebirth
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| 100. | Bisnap Plays Isaac: Rebirth Episode 54 - Often | 23,401 | Let's Play | The Binding of Isaac: Rebirth
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