| 401. | All of these CARRIED this in the end | The Binding of Isaac: Repentance | 42 | | The Binding of Isaac: Rebirth
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| 402. | Enter Room, UNLOAD 300 Tears | The Binding of Isaac: Repentance | 43 | | The Binding of Isaac: Rebirth
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| 403. | Light Cuts | 33 | | The Binding of Isaac: Rebirth
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| 404. | You'd think this is an EASY WIN, but... | 59 | | The Binding of Isaac: Rebirth
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| 405. | Twisted Toxicity | The Binding of Isaac: Repentance | 44 | | The Binding of Isaac: Rebirth
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| 406. | Giga Krampus | 36 | | The Binding of Isaac: Rebirth
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| 407. | The Ultimate Lil Brim CARRY | 49 | | The Binding of Isaac: Rebirth
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| 408. | Sometimes the RUN WINNER shows up at the End | 28 | | The Binding of Isaac: Rebirth
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| 409. | All the good stuff (at once) | 42 | | The Binding of Isaac: Rebirth
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| 410. | Grim Meower | 50 | | The Binding of Isaac: Rebirth
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| 411. | Love these Builds | 58 | | The Binding of Isaac: Rebirth
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| 412. | Incredible Star(t) | 48 | | The Binding of Isaac: Rebirth
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| 413. | I looked and felt like the GRIM REAPER | 47 | | The Binding of Isaac: Rebirth
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| 414. | Blue Flame Machine Gun | The Binding of Isaac: Repentance | 71 | | The Binding of Isaac: Rebirth
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| 415. | More Like Sacred Win Am I Right | 61 | | The Binding of Isaac: Rebirth
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| 416. | These Two Were Made For Each Other | The Binding of Isaac: Repentance | 61 | | The Binding of Isaac: Rebirth
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| 417. | Guiding Light | The Binding of Isaac: Repentance | 36 | | The Binding of Isaac: Rebirth
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| 418. | The Shocking Continues | 56 | | The Binding of Isaac: Rebirth
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| 419. | High Damage Plops | The Binding of Isaac: Repentance | 55 | | The Binding of Isaac: Rebirth
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| 420. | Greedier is SO EASY (when you find all the OP stuff) | The Binding of Isaac: Repentance | 56 | | The Binding of Isaac: Rebirth
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| 421. | This BUFF made Skinny Odd Mushroom INCREDIBLE | 45 | | The Binding of Isaac: Rebirth
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| 422. | Eden Roulette LIVE | 11 | |
|
| 423. | Accidental Speedrun | The Binding of Isaac: Repentance | 62 | | The Binding of Isaac: Rebirth
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| 424. | This INSANE Combo could still LOSE your Run! | 33 | | The Binding of Isaac: Rebirth
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| 425. | I Never realised how Good this Synergy is | 35 | | The Binding of Isaac: Rebirth
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| 426. | Shielded Tear Barrage | 41 | | The Binding of Isaac: Rebirth
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| 427. | My Favourite "awkward" Item! | 33 | | The Binding of Isaac
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| 428. | Always a Greed Mode Classic | 40 | | The Binding of Isaac: Rebirth
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| 429. | So. Many. BABIES. | 47 | | The Binding of Isaac: Rebirth
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| 430. | When you keep finding great Items | The Binding of Isaac: Repentance | 46 | | The Binding of Isaac: Rebirth
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| 431. | Brimstone Overload | 50 | |
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| 432. | A Big Lasers Solves All Problems | 35 | | The Binding of Isaac: Rebirth
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| 433. | Some Runs Really Do Have It All | The Binding of Isaac: Repentance | 46 | | The Binding of Isaac: Rebirth
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| 434. | Hardest "Easy Win" of my Life | 64 | | The Binding of Isaac: Rebirth
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| 435. | I had to go to Mega Satan and this was the best I got | 33 | | The Binding of Isaac: Rebirth
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| 436. | Double the Eyes (Of Belial) | The Binding of Isaac: Repentance | 50 | | The Binding of Isaac: Rebirth
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| 437. | I Love adding Tear Rate to HOLY LIGHT | 48 | | The Binding of Isaac: Rebirth
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| 438. | Bouncy Ball Bath | 43 | | The Binding of Isaac: Rebirth
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| 439. | Multipliers and Proptosis still GO HARD | The Binding of Isaac: Repentance | 56 | | The Binding of Isaac: Rebirth
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| 440. | I have become Conquest | 34 | | The Binding of Isaac: Rebirth
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| 441. | I found my FAVOURITE Item and DESTROYED everything | The Binding of Isaac: Repentance | 42 | | The Binding of Isaac: Rebirth
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| 442. | S P I N D O W N | 45 | | The Binding of Isaac: Rebirth
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| 443. | Flies and Spiders | The Binding of Isaac: Repentance | 42 | | The Binding of Isaac: Rebirth
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| 444. | Buff Pair | The Binding of Isaac: Repentance | 53 | | The Binding of Isaac: Rebirth
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| 445. | These two are SO MUCH FUN together | 45 | | The Binding of Isaac: Rebirth
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| 446. | Magnetizing EVERYTHING | The Binding of Isaac: Repentance | 43 | | The Binding of Isaac: Rebirth
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| 447. | I tried out BUFFED ABYSS so you don't have to | The Binding of Isaac: Repentance | 55 | | The Binding of Isaac: Rebirth
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| 448. | My Most INSANE Run of 2025 | 60 | | The Binding of Isaac: Rebirth
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| 449. | Holy Brimaw | The Binding of Isaac: Repentance | 54 | | The Binding of Isaac: Rebirth
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| 450. | Ultimate Firespam | The Binding of Isaac: Repentance | 56 | | The Binding of Isaac: Rebirth
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| 451. | Twisted Pair leads to the WILDEST Tear Builds | 52 | | The Binding of Isaac: Rebirth
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| 452. | Defense is the backbone of every Juggernaut Build | The Binding of Isaac: Repentance | 53 | | The Binding of Isaac: Rebirth
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| 453. | This was surprisingly effective | The Binding of Isaac: Repentance | 39 | | The Binding of Isaac: Rebirth
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| 454. | Magneticac | The Binding of Isaac: Repentance | 42 | | The Binding of Isaac: Rebirth
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| 455. | So I Took The Wiz.... | The Binding of Isaac: Repentance | 48 | | The Binding of Isaac: Rebirth
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| 456. | The KINGS of CLUTCH! | The Binding of Isaac: Repentance | 35 | | The Binding of Isaac: Rebirth
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| 457. | Rollercoaster | The Binding of Isaac: Repentance | 49 | | The Binding of Isaac: Rebirth
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| 458. | This Item makes Runs TRIVIAL | The Binding of Isaac: Repentance | 75 | | The Binding of Isaac: Rebirth
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| 459. | I'm the Milkman | 57 | | The Binding of Isaac: Rebirth
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| 460. | Double the Triple | The Binding of Isaac: Repentance | 35 | | The Binding of Isaac: Rebirth
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| 461. | King of the Cats | 35 | | The Binding of Isaac: Rebirth
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| 462. | The Mega Satan Deleter | 31 | | The Binding of Isaac: Rebirth
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| 463. | How Good Is SOY MILK? | Basement Blather Ep. 3 | 46 | | The Binding of Isaac
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| 464. | When the game just won't give you tears | 39 | | The Binding of Isaac: Rebirth
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| 465. | THE CANDLE CARRY | The Binding of Isaac: Repentance | 30 | | The Binding of Isaac: Rebirth
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| 466. | This Item Makes Death's List SO EASY | The Binding of Isaac: Repentance | 39 | | The Binding of Isaac: Rebirth
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| 467. | How to get 57 Luck in one Run | 45 | | The Binding of Isaac: Rebirth
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| 468. | This Start goes SO HARD | The Binding of Isaac: Repentance | 44 | | The Binding of Isaac: Rebirth
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| 469. | Winged Warrior | 52 | | The Binding of Isaac: Rebirth
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| 470. | They became (my) best friends | 36 | | The Binding of Isaac: Rebirth
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| 471. | Pulling the Tearspam together | The Binding of Isaac: Repentance | 50 | | The Binding of Isaac: Rebirth
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| 472. | This Combo has been winning runs for a decade | 53 | | The Binding of Isaac: Rebirth
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| 473. | ROCK BOTTOM START feat. Infiniports | 59 | | The Binding of Isaac: Rebirth
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| 474. | One of the OG BUSTED Combos! | The Binding of Isaac: Repentance | 48 | | The Binding of Isaac: Rebirth
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| 475. | FIRE MIND Starts are SCARY, but... | 49 | | The Binding of Isaac: Rebirth
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| 476. | Adding Tears to TRACTOR BEAM always goes HARD | 49 | | The Binding of Isaac: Rebirth
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| 477. | I tried out BUFFED MARS so you don't have to | The Binding of Isaac: Repentance | 46 | | The Binding of Isaac: Rebirth
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| 478. | Never seen so many SPIDERS! | 60 | | The Binding of Isaac: Rebirth
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| 479. | A Thousand Stabs | 43 | | The Binding of Isaac: Rebirth
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| 480. | Vortex of Scythes | The Binding of Isaac: Repentance | 51 | | The Binding of Isaac: Rebirth
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| 481. | Godly Greed | 47 | | The Binding of Isaac: Rebirth
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| 482. | Budget Sacred Scythes | 38 | | The Binding of Isaac: Rebirth
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| 483. | Tear Spam and Tech Zero leads to DESTRUCTION | The Binding of Isaac: Repentance | 60 | | The Binding of Isaac: Rebirth
|
| 484. | Cat goes Boom | The Binding of Isaac: Repentance | 47 | | The Binding of Isaac: Rebirth
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| 485. | Probably my most insane Basement to date | 176 | | The Binding of Isaac: Rebirth
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| 486. | Not Only Strong in Greedier | The Binding of Isaac: Repentance | 50 | | The Binding of Isaac: Rebirth
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| 487. | Maw of the Haemolacria | 46 | | The Binding of Isaac: Rebirth
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| 488. | Let me add some Lasers to my Laser | 50 | | The Binding of Isaac: Rebirth
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| 489. | Close | The Binding of Isaac: Repentance | 47 | | The Binding of Isaac: Rebirth
|
| 490. | Eden Roulette LIVE | 5 | |
|
| 491. | Is this the most EXCITING starting Item in Isaac? | 59 | | The Binding of Isaac: Rebirth
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| 492. | Sometimes all you need is a giant Laser | 43 | | The Binding of Isaac: Rebirth
|
| 493. | This Combo has always been insane | 40 | | The Binding of Isaac: Rebirth
|
| 494. | Rings of DAMAGE | 49 | | The Binding of Isaac: Rebirth
|
| 495. | When BRIMSTONE transcends Dimensions | 52 | | The Binding of Isaac: Rebirth
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| 496. | Multiplying Babies | 49 | | The Binding of Isaac: Rebirth
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| 497. | I Love CHOCOLATE MILK | The Binding of Isaac: Repentance | 37 | | The Binding of Isaac: Rebirth
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| 498. | Build so Good I turned it into a Speedrun | 51 | | The Binding of Isaac: Rebirth
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| 499. | Just BURN down the whole Basement | 53 | | The Binding of Isaac: Rebirth
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| 500. | PROPTOSIS is the best and worst Item at the same time | The Binding of Isaac: Repentance | 43 | | The Binding of Isaac: Rebirth
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