| 1. | Isaac Afterbirth Unlocking Lilith [Greed Mode] | 1,756 | | The Binding of Isaac: Rebirth
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| 2. | Isaac Scrooge Mode!? [Challenge] | 255 | | The Binding of Isaac: Rebirth
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| 3. | Isaac Afterbirth Greed mode [Familiar Frenzy] | 148 | | The Binding of Isaac: Rebirth
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| 4. | Binding of Isaac Challenges [Pitch Black] | 123 | | The Binding of Isaac: Rebirth
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| 5. | Isaac Afterbirth Greed mode [Shot speed up] | 123 | | The Binding of Isaac: Rebirth
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| 6. | Isaac Afterbirth Greed mode [20/20] | 109 | | The Binding of Isaac: Rebirth
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| 7. | Isaac Afterbirth Greed mode [Tape worm] | 103 | | The Binding of Isaac: Rebirth
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| 8. | Isaac Afterbirth Greed mode [Dodging] | 99 | | The Binding of Isaac: Rebirth
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| 9. | Isaac Afterbirth Greed mode [Insane Bomber] | 99 | | The Binding of Isaac: Rebirth
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| 10. | Isaac Afterbirth Greed mode [Lucky] | 98 | | The Binding of Isaac: Rebirth
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| 11. | Isaac Afterbirth Greed mode [Reroll] | 96 | | The Binding of Isaac: Rebirth
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| 12. | Isaac Afterbirth Greed mode [Stinky] | 88 | | The Binding of Isaac: Rebirth
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| 13. | Binding of Isaac Challenges [High Brow] | 82 | | The Binding of Isaac: Rebirth
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| 14. | Isaac Afterbirth Greed mode [Mini Me] | 82 | | The Binding of Isaac: Rebirth
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| 15. | Isaac Afterbirth Greed mode [Splash] | 71 | | The Binding of Isaac: Rebirth
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| 16. | Isaac Afterbirth [Daily] #1 | 70 | | The Binding of Isaac: Rebirth
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| 17. | Binding of Isaac Challenges [Darkness Falls] | 67 | | The Binding of Isaac: Rebirth
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| 18. | Binding of Isaac Challenges [Head Trauma] | 57 | | The Binding of Isaac: Rebirth
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| 19. | Isaac Afterbirth Greed mode [Zap] | 47 | | The Binding of Isaac: Rebirth
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