| 401. | Villains Defeat 378 | 79 | |
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| 402. | Villains Defeat 200 | 79 | | Splinter Cell: Double Agent
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| 403. | Villains Defeat 403 | 78 | |
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| 404. | Villains Defeat 61 | 78 | | Super Mario Bros.
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| 405. | Villains Defeat 451 | 78 | |
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| 406. | Villains Defeat 57 | 78 | | Unreal II: The Awakening
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| 407. | Villains Defeat 350 | 78 | |
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| 408. | Defeat of My Favorite Cartoon Villains Part 25 | 78 | |
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| 409. | Defeat of My Favorite Anime Villains Part II | 77 | |
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| 410. | Villains Defeat 305 | 77 | |
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| 411. | Heroes Defeat 28 | 77 | | Call of Duty: Advanced Warfare
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| 412. | Defeat of My Favorite Video Game Villains Part 8 | 77 | |
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| 413. | Villains Defeat 141 | 77 | |
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| 414. | Villains Defeat 39 | 77 | |
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| 415. | Villains Defeat 367 | 77 | |
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| 416. | Villains Defeat 285 | 77 | | Ghost Recon Wildlands
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| 417. | Defeat of My Favorite TV Villains Part 16 | 77 | |
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| 418. | Villains Defeat 248 (Easter Special) | 77 | |
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| 419. | Defeat of My Favorite Anime Villains Part XI | 77 | |
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| 420. | Villains Defeat 436 | 77 | |
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| 421. | Anger HATES Barney | 76 | |
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| 422. | Villains Defeat 389 | 76 | | Fallout 2
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| 423. | Villains Defeat 174 | 76 | |
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| 424. | Villains Defeat 432 | 76 | | Cyberpunk 2077
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| 425. | Villains Defeat 253 | 76 | |
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| 426. | Villains Defeat 349 | 75 | |
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| 427. | Villains Defeat 455 | 75 | |
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| 428. | Villains Defeat 303 | 75 | | Star Wars Battlefront II
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| 429. | Villains Defeat 71 | 75 | |
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| 430. | Dr. Nefarious - Deleted Scene | 75 | |
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| 431. | Villains Defeat 362 | 75 | |
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| 432. | Villains Defeat 177 | 75 | | Uncharted 4: A Thief's End
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| 433. | Villains Defeat 56 | 75 | |
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| 434. | Villains Defeat 321 | 75 | |
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| 435. | Villains Defeat 169 | 75 | |
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| 436. | Villains Defeat 354 | 74 | |
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| 437. | Villains Defeat 52 | 74 | |
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| 438. | Villains Defeat 462 | 74 | |
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| 439. | Defeat of My Favorite TV Villains Part 9 | 74 | |
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| 440. | Villains Defeat 385 | 74 | |
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| 441. | Villains Defeat 45 | 74 | | Castlevania: Lords of Shadow
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| 442. | Villains Defeat 273 | 74 | |
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| 443. | Villains Defeat 55 | 74 | |
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| 444. | Villains Defeat 346 | 74 | |
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| 445. | Villains Defeat 158 | 74 | |
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| 446. | Villains Defeat 224 | 74 | |
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| 447. | Villains Defeat 460 | 74 | |
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| 448. | Villains Defeat 49 | 74 | |
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| 449. | Villains Defeat 48 | 73 | |
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| 450. | Villains Defeat 347 | 73 | |
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| 451. | Heroes Defeat 32 | 73 | |
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| 452. | Villains Defeat 40 | 73 | |
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| 453. | Villains Defeat 441 | 73 | |
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| 454. | Villains Defeat 292 | 73 | |
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| 455. | Disney Villains Defeats | 73 | |
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| 456. | Villains Defeat 457 | 72 | |
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| 457. | Villains Defeat 364 | 72 | |
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| 458. | Villains Defeat 38 | 72 | |
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| 459. | Villains Defeat 405 | 72 | |
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| 460. | Villains Defeat 324 | 72 | |
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| 461. | Villains Defeat 122 | 72 | | Crisis Core: Final Fantasy VII
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| 462. | Villains Defeat 474 | 72 | |
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| 463. | Villains Defeat 353 | 72 | | Ori and the Blind Forest
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| 464. | Villains Defeat 195 | 72 | | Teenage Mutant Ninja Turtles: Out of the Shadows
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| 465. | Defeat of My Favorite Movie Villains Part LXXIV | 72 | |
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| 466. | Villains Defeat 363 | 71 | |
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| 467. | Villains Defeat 496 | 78 | |
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| 468. | Villains Defeat 377 | 71 | |
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| 469. | Villains Defeat 443 | 71 | |
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| 470. | Defeat of My Favorite Anime Villains Part XII | 71 | |
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| 471. | Villains Defeat 406 | 71 | | The Witcher 3: Wild Hunt
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| 472. | Villains Defeat 435 | 71 | |
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| 473. | Villains Defeat 322 | 71 | |
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| 474. | Villains Defeat 151 | 71 | |
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| 475. | Villains Defeat 469 (Halloween Special!) | 71 | |
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| 476. | Villains Defeat 348 | 71 | | Clock Tower II: The Struggle Within
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| 477. | Villains Defeat 241 | 71 | |
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| 478. | Villains Defeat 323 | 71 | |
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| 479. | Villains Defeat 76 | 70 | |
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| 480. | Villains Defeat 487 | 71 | |
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| 481. | Villains Defeat 453 (Christmas Special!) | 70 | |
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| 482. | Villains Defeat 409 | 70 | |
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| 483. | Villains Defeat 211 | 70 | |
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| 484. | Villains Defeat 295 | 69 | |
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| 485. | Villains Defeat 143 (Re-Upload) | 69 | |
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| 486. | Villains Defeat 475 | 69 | |
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| 487. | Villains Defeat 63 | 69 | |
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| 488. | Villains Defeat 244 | 69 | | The Last Guardian
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| 489. | Villains Defeat 463 | 69 | | Call of Duty: Black Ops III
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| 490. | Villains Defeat 442 | 69 | | Watch Dogs: Legion
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| 491. | Villains Defeat 101 | 69 | |
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| 492. | Villains Defeat 368 | 69 | |
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| 493. | Villains Defeat 311 | 69 | |
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| 494. | Villains Defeat 504 | 86 | |
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| 495. | Villains Defeat 279 | 69 | | Rodea the Sky Soldier
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| 496. | Villains Defeat 459 | 68 | |
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| 497. | Villains Defeat 53 | 68 | |
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| 498. | Defeat of My Favorite YouTube Villains Part 27 | 68 | |
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| 499. | Defeat of My Favorite Anime Villains Part XIII | 68 | |
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| 500. | Villains Defeat 79 | 68 | |
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