| 401. | Earth just made a new space friend! | 193,345 | |
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| 402. | Can Coral Reefs Survive Climate Change? | 192,275 | |
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| 403. | Paying Attention in the Digital Age | 186,352 | |
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| 404. | The Incredible Biological Connection We All Share With Our Mom | 184,781 | Vlog |
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| 405. | How Many Species are in Your Backyard? | 184,056 | |
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| 406. | Why Dung Beetles Stare At the Stars | IN OUR NATURE | 182,372 | |
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| 407. | Ask Joe Stuff - 2 Million Subscribers Edition! | 182,118 | |
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| 408. | The Scale of the Universe | 178,523 | |
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| 409. | Why doesn’t ❤️ look like an ACTUAL HEART 🫀 ?! | 178,128 | |
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| 410. | Custom gene editing is here… and it just saved this baby’s life! 🧬👶 | 177,272 | |
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| 411. | How To Read Science News | 175,927 | Guide |
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| 412. | Why NASA Punched an Asteroid | 174,054 | |
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| 413. | Between Two Tesla Coils! - 360 Video | 171,784 | |
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| 414. | This Apollo mission almost ended in MUTINY | 169,472 | |
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| 415. | The BIGGEST camera ever is making a movie of the universe | 168,679 | |
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| 416. | The Superb Owl! | 165,940 | |
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| 417. | Can you figure out the Castle Illusion? 🏰🧠🤯 | 162,115 | |
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| 418. | The Sun Is A Magnet! | 160,808 | |
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| 419. | What Synesthesia Feels Like | 160,583 | |
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| 420. | The Universe in a Glass of Wine (Richard Feynman Remixed) | 160,085 | |
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| 421. | Why Sending Messages to Extraterrestrials Could Be Risky (Dark Forest Hypothesis) | 159,248 | |
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| 422. | Ask Joe Stuff #6 | 154,437 | |
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| 423. | How Humans Ruined and Rescued an Ocean Paradise | 152,144 | |
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| 424. | The Beautiful Cycles of Carbon and Oxygen In Your Body | 150,351 | |
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| 425. | 360˚ Inside an ICE CAVE!! | 149,680 | |
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| 426. | Why Do We Go to Space? | 147,385 | |
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| 427. | Should You Feel Guilty About Climate Change? - featuring Al Gore | 145,726 | |
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| 428. | IN YOUR FACE EXPLOSIVE CHEMISTRY!! (VR180) | 135,550 | |
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| 429. | It's Okay To Be Smart is on Patreon! | 129,984 | |
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| 430. | The Argument for De-Extinction: EXPLAINED | 127,345 | | Extinction
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| 431. | Mexico’s Monarch Butterfly Migration in VR180 | 124,242 | |
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| 432. | Did we just figure out the whale alphabet? | 124,145 | |
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| 433. | The Strange Psychology of Superfans (with @smartereveryday) | 120,354 | |
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| 434. | This is how to tag a BLUE WHALE 🐋 with a drone (for science!!) | 117,825 | |
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| 435. | The fastest animal on Earth? It’s not what you think! | 115,291 | |
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| 436. | There Are Millions of Skeletons Hidden In Washington, DC | 115,260 | |
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| 437. | Why Do We Vote? It's Not For the Reasons You Think… | 110,604 | |
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| 438. | Sunburn, Sweat and the Science of Summer! | 109,864 | |
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| 439. | Why I ❤ PBS | 106,154 | |
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| 440. | Can you explain the falling coffee cup trick? | 103,251 | |
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| 441. | Can this apple defy gravity? 🍎 | 97,631 | |
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| 442. | Ask Joe Stuff #5 | 96,970 | |
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| 443. | This is what space sounds like | 96,106 | |
|
| 444. | Making Music From Space! | 90,923 | |
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| 445. | Do space rocks ever actually hit people?! ☄️ | 89,130 | |
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| 446. | Are You Sharing a Breath With Isaac Newton? | 86,793 | |
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| 447. | I figured out how much wood a woodchuck could actually chuck | 81,902 | |
|
| 448. | This physics trick will blow people's minds | 79,842 | |
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| 449. | This beetle might have nature's most interesting camouflage | 79,474 | |
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| 450. | That one time the CIA spied on climate change 🤫 | 76,121 | |
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| 451. | Ask Joe Stuff #1 | 75,850 | |
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| 452. | Ask Joe Stuff #4 | 74,640 | |
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| 453. | Ask Joe Stuff #3 | 62,225 | |
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| 454. | Making 🔥 by Smashing Balls | 61,918 | |
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| 455. | This is why coral reefs are in BIG trouble 😳 | 60,706 | |
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| 456. | Ask Joe Stuff #2 | 58,679 | |
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| 457. | Guess the animal poop! Serengeti edition 💩 | 55,416 | |
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| 458. | It's Okay To Be Smart - Bloopers Vol. 2 | 54,783 | |
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