| 1. | binding of isaac repentance: the only good mod | 1,467 | | The Binding of Isaac: Rebirth
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| 2. | The Binding of Isaac Repentance: fart noises | 1,442 | | The Binding of Isaac: Rebirth
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| 3. | Binding of Isaac: Repentance - Brimstone synergizes with anything | 314 | | The Binding of Isaac: Rebirth
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| 4. | amnesia | 78 | | The Binding of Isaac: Rebirth
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| 5. | paused bone | 78 | | The Binding of Isaac: Rebirth
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| 6. | psychic baby | 60 | | The Binding of Isaac: Rebirth
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| 7. | dangerouslypredictable explains the joke | 57 | | The Binding of Isaac: Rebirth
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| 8. | when afterbirth+ gifts you a broken run | 45 | | The Binding of Isaac: Rebirth
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| 9. | "yeah i like greedier" | 39 | | The Binding of Isaac: Rebirth
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| 10. | The Binding of Isaac Repentance: Challenge #45 is funny. | 33 | | The Binding of Isaac: Rebirth
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| 11. | lucky riches | 33 | | The Binding of Isaac: Rebirth
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| 12. | Afterbirth+ True Co-Op moments: Milk! breaks all | 29 | | The Binding of Isaac: Rebirth
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| 13. | friend | 23 | | The Binding of Isaac: Rebirth
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| 14. | Afterbirth+ Breaking Runs: Who doesn't love sprinkler? | 20 | | The Binding of Isaac: Rebirth
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| 15. | cracked | 19 | | The Binding of Isaac: Rebirth
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| 16. | technology | 18 | | The Binding of Isaac: Rebirth
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| 17. | scam | 17 | | The Binding of Isaac: Rebirth
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| 18. | Binding of Isaac afterbirth: This is only the last floor. | 16 | | The Binding of Isaac: Rebirth
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| 19. | duke | 15 | | The Binding of Isaac: Rebirth
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| 20. | The Binding of Isaac Repentance: tainted lost good | 15 | | The Binding of Isaac: Rebirth
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| 21. | damocles | 13 | | The Binding of Isaac: Rebirth
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| 22. | cards | 13 | | The Binding of Isaac: Rebirth
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| 23. | me and the boys failing to annihilate the beast in repentance | 13 | | The Binding of Isaac: Rebirth
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| 24. | defeat | 12 | | The Binding of Isaac: Rebirth
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| 25. | What have I done... | 11 | | The Binding of Isaac: Rebirth
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| 26. | Binding of Isaac Repentance: achieving godhood with Tainted Cain (Greedier) | 11 | | The Binding of Isaac: Rebirth
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| 27. | crimson champion | 10 | | The Binding of Isaac: Rebirth
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| 28. | The Binding of Isaac Repentance: Tainted Bethany "The Immortal" | 8 | | The Binding of Isaac: Rebirth
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| 29. | What have I become... Again... | 3 | | The Binding of Isaac: Rebirth
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