Top 100 The Binding of Isaac: Rebirth Videos With The Most Comments by JaytheRocketManTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.The Binding of Isaac: Afterbirth Seed Ipecac + Pyromaniac40The Binding of Isaac: Rebirth 2.Let's Play Binding of Isaac Gameplay [Half-Heart] The Binding of Isaac: Afterbirth Gameplay20Let's PlayThe Binding of Isaac: Rebirth 3.I GOT HACKED!! - Life Story | Binding of Isaac: Afterbirth Gameplay20The Binding of Isaac: Rebirth 4.The Binding of Isaac: Afterbirth OP Seed Tech X + Brimstone + Sad Bombs + Scatter Bombs18The Binding of Isaac: Rebirth 5.The Binding of Isaac: Afterbirth Seed Brimstone + Triple Shot + Multidimensional Baby14The Binding of Isaac: Rebirth 6.The Binding of Isaac: Afterbirth OP Seed Mutant Spider + 20/20 + Inner Eye14The Binding of Isaac: Rebirth 7.The Binding of Isaac: Afterbirth Seed Monstro's Lung + Ludovico Technique9The Binding of Isaac: Rebirth 8.Let's Play Binding of Isaac: Afterbirth Gameplay - Defeating Mom's Heart!8Let's PlayThe Binding of Isaac: Rebirth 9.The Binding of Isaac: Afterbirth OP Seed Tech X + Spoon Bender7The Binding of Isaac: Rebirth 10.The Binding of Isaac: Afterbirth Seed Brimstone + Spoon Bender + Sad Bombs + Scatter Bombs6The Binding of Isaac: Rebirth 11.Binding of Isaac: Afterbirth Seed Guppy Transformation6The Binding of Isaac: Rebirth 12.The Binding of Isaac: Afterbirth Seed TECHNOLOGY + 20/20 + LORD OF THE PIT6VlogThe Binding of Isaac: Rebirth 13.The Binding of Isaac: Afterbirth OP Seed FUN Guy Transformation!4The Binding of Isaac: Rebirth 14.The Binding of Isaac: Afterbirth OP Seed Mutant Spider + Inner Eye + Scorpio + Goat's Head3The Binding of Isaac: Rebirth 15.Hush Boss Fight - The Binding of Isaac: Afterbirth OP Seed2The Binding of Isaac: Rebirth 16.The Binding of Issac Afterbirth: Livestream2The Binding of Isaac: Rebirth 17.The Binding of Isaac Gameplay [Defeating Mom] The Binding of Isaac: Afterbirth Gameplay2The Binding of Isaac: Rebirth 18.The Binding of Isaac: Afterbirth OP Seed Spun & FUN Guy Transformation!1The Binding of Isaac: Rebirth 19.JayTheRocketMan - Channel Update 3/9/20170VlogThe Binding of Isaac: Rebirth Top 100 » 200 » 300 » 400 » 500