| 1. |  Retro Game On | The Sega Mega Modem: Wonders of the Retro Gaming World | 5,342 | |
| 2. | KeepetClassy | Comix Zone: I Banish you to Bad Fan Art Comics | 2,590 | |
| 3. | Tenka | Comix Zone (Genesis) - Speedrun in 19:59 [INSANE First Attempt] | 932 | |
| 4. | Diamond Longplays | Comix Zone (Gen) Longplay [441] | 730 | |
| 5. | Zlobster | 🎮 Comix Zone (Sega)- Олдскульное прохождение! | 435 | |
| 6. | Retro Longplays | [Longplay] GBA - Comix Zone | 430 | |
| 7. | Open Rhythm Music | Sega Tunes: Last to Follow | 356 | |
| 8. | 1 Coin Only | Comix Zone - Calcium Kid Hack (Genesis) & Sonic Classic Heroes (Genesis) | 290 | |
| 9. | Longplay Library | Comix Zone (🎮GEN) - ✨4K 60FPS Longplay | 100% Completion | No Commentary | 251 | |
| 10. | Legacy Loop | 👻 Like Slimer From GhostBusters - Comix Zone Sega MegaDrive | Genesis #sega #gameplay #ghostbusters | 250 | |
| 11. | GLitch | Comix Zone, это одна из ЛУЧШИХ игр для Sega | 249 | |
| 12. | ...Since Spacies | Sega Mega Drive Ultimate Collection - Comix Zone | 238 | |
| 13. | 1 Coin Only | TaleSpin (NES) & Comix Zone (Genesis) | 210 | |
| 14. | GAMES ACROSS TIME | Celebrating 30 Years of Comix Zone – Sega’s Comic Book Masterpiece! 📚⚡🕹️ | 186 | |
| 15. | 1 Coin Only | Whatever Wednesday: Fans Pick the Games! (Episode 6 - Jan 16th 2019) | 170 | Show |
| 16. | GLitch | ИГРА КОТОРОЙ БОЛЬШЕ 20ТИ ЛЕТ Comix Zone Classic | 168 | |
| 17. | Legacy Loop | ⚡️🐀 - Electric Rat - Comix Zone Sega MegaDrive | Genesis #sega #gameplay #comixzone | 92 | |
| 18. | Death Sandals | Comix Zone (Windows 3.1): A Literal Self Insert | 87 | |
| 19. | Retro Longplays | [Longplay] Genesis - Comix Zone | 87 | |
| 20. | RaiZdbyDINGOES | Retro Videogame Pickups 15/ 11/ 13 | 68 | |
| 21. | MichtyMaxx | GG Portrait Pat Chan - Sega Game Gear - Review / Let's Play / Reaction by PRGR | 52 | |
| 22. | GuacaTypeBeat | Comix Zone - NOSTALGIA TRIP | 50 | |
| 23. | Gaming 4 XP | Retro Gaming - Comix Zone | 39 | |
| 24. | Fully Hek | SEE YAH! COMIX ZONE - PLAY IT!! | 37 | |
| 25. | GLitch | COMIX ZONE: EPISODE 1 | 30 | |
| 26. | Legacy Loop | Retro Play - Comix Zone | Sega MegaDrive & Genesis #sega #gameplay #comixzone | 14 | |
| 27. | Gamerleftunder2 | Comix Zone WOW THIS GAME SO COOL I love it =D if u want see more Let me know | 10 | |
| 28. | SHOTSY2222 | Comix Zone (IOS) Gameplay With Live Commentary + Thoughts | 10 | |
| 29. | Neon The Nights Chao (Ghostly Winds) | Comix zone game play | 9 | |
| 30. | Gamerleftunder2 | Comix Zone / # 2 HELL YEA WE BACK in the COMIX ZONE! | 9 | |
| 31. | SIRSMP | I Livestreamed Myself Playing Sega Genesis Comix Zone 1995 | 8 | |
| 32. | Open Rhythm Music | Sega Tunes CD - Into The Zone (Comix Zone) | 6 | |
| 33. | Open Rhythm Music | Sega Tunes CD - 10,000 Knives (Comix Zone) | 3 | |
| 34. | CruznMJD Productions | Ep 399 - Video Game Intro - Comix Zone | 3 | |
| 35. | Open Rhythm Music | Sega Tunes CD - Woe is the world (Comix Zone) | 3 | |
| 36. | Open Rhythm Music | Sega Tunes CD - Seen it For Days (Comix Zone) | 3 | |
| 37. | Gamerleftunder2 | Comix Zone / #4 wait what the hell is this how do i pass it | 2 | |
| 38. | Open Rhythm Music | Sega Tunes CD - Last to Follow (Comix Zone) | 2 | |
| 39. | Gamerleftunder2 | Comix ZOne / #4 OMG! LAST BOSS WHAT DO I DO! I FOUND OUT LATER BUT MAYBE FINAL! | 1 | |
| 40. | Open Rhythm Music | Sega Tunes CD - Feed My Disease (Comix Zone) | 1 | |
