| 1. |  Adam McDermott | Dead Space 2 - Platinum Journey | 434 | |
| 2. | Deebeegeek | Make us whole again...again... Dead Space 2 for the FIRST time | 271 | Walkthrough |
| 3. | Deebeegeek | The ENDING of Dead Space 2 made me RAGE so hard it HURT | 225 | |
| 4. | P.B. Horror Gaming | Dead Space 2 | 1440P | Full Game Longplay Walkthrough No Commentary【PC►Visually Enhanced】 | 141 | Walkthrough |
| 5. | Deebeegeek | Is Isaac a SIMP?? - Dead Space 2 For the FIRST time (PART 2) | 102 | |
| 6. | Adam McDermott | Personal Experience with Dead Space 2 | 85 | |
| 7. | Deebeegeek | I can't believe I'm back on the USG Ishimura.. | 79 | Let's Play |
| 8. | Deebeegeek | The MOST BADASS scene in Dead Space 2!! | 73 | |
| 9. | Ross Mahon | AVP3 - Alien Campaign Start | 22 | |
| 10. | Jigzaw_Killer | Dead Space 2 Playthrough - Zealot Difficulty PART 1 | 21 | Let's Play |
| 11. | Jigzaw_Killer | Dead Space 2 Speedrun Zealot Difficulty 2:30:48 | 21 | |
| 12. | BenchmarkLabs | Dead Space: GTX 1060 (OC) | I5 6400 | Benchmark (1080p60FPS) | 15 | |
| 13. | P.B. Horror Gaming | DEAD SPACE 2 | FULL GAME | Gameplay Walkthrough No Commentary 4K 60FPS | 12 | Walkthrough |
| 14. | CyberHoudini | DESCENT INTO MADNESS!! | Dead Space 2 Walkthrough PART 1 | 9 | Walkthrough |
| 15. | Jigzaw_Killer | Dead Space 2 Playthrough - Zealot Difficulty PART 2 | 8 | |
| 16. | Zettoman | Dead Space 2 ReShade RT(Marty McFly pathtracing shader) 1060+6700 | 8 | |
| 17. | Jigzaw_Killer | Dead Space 2 Playthrough - Zealot Difficulty Part 3 Finale | 7 | |
| 18. | Ross Mahon | AVP3 - Alien Campaign - HQ | 7 | |
| 19. | Adam McDermott | Dead Space - Smash Cut | 7 | |
| 20. | Cherry | I actually can't handle this | Dead Space 2 | 6 | |
| 21. | Sacky Livestreams | How 2 face your fears - Dead Space edition | 4 | |
| 22. | BigBossIncarnate | Dead Space 2 PS3 | Severed DLC then Main Story | 4 | Let's Play |
| 23. | Adam McDermott | Dead Space 2 Zealot Ep. 1 - Where Am I? | 3 | |
| 24. | CruachanKeith | Let's Play Dead Space 2 | 3 | Let's Play |
| 25. | Adam McDermott | Dead Space 2 Zealot Ep. 2 - Here I am! | 3 | |
| 26. | CyberHoudini | CHILDREN OF THE MARKER | Dead Space 2 Walkthrough PART 2 | 3 | Walkthrough |
| 27. | Just Tom | JustTom Plays | Dead Space 2 | Part 5 | 3 | Let's Play |
| 28. | Just Tom | JustTom Plays | Dead Space 2 | Part 3 | 3 | Let's Play |
| 29. | PSX Gaming Memories | Max Racer PS1 Review - Obscure PS1 Arcade Racing Game - PS1 Japan Only Release... | 3 | Review |
| 30. | CyberHoudini | AND THE REST IS SILENCE | Dead Space 2 Walkthrough PART 4 ENDING | 3 | Walkthrough |
| 31. | Just Tom | JustTom Plays | Dead Space 2 | Part 2 | 2 | Let's Play |
| 32. | CharleZ BronsoN | Dead Space 2 (DEMO) [HD] | 2 | |
| 33. | CruachanKeith | The Creepiest Survival Horror Level Ever!!! | 2 | |
| 34. | Adam McDermott | NO BABIES FOR ISAAC - Dead Space 2 Gamplay | 2 | |
| 35. | CyberHoudini | PRELUDE TO DARKNESS | Dead Space 2 Walkthrough PART 3 | 2 | Walkthrough |
| 36. | MazManZero | Dead Space 2 Multiplayer Gameplay 2 (1 round) | 2 | |
| 37. | JamesH97 Gaming | Dead Space Let's Play #1 (Live Stream) | 2 | Let's Play |
| 38. | BigBossIncarnate | Dead Space 2 PC | Zealot Difficulty Part 1 | 2 | |
| 39. | DeeBeeHive - VOD Channel | It just got worse... | Dee Plays - Dead Space 2 (2/4) | 1 | Let's Play |
| 40. | Palnai | Dead Space 2 part 2a - The First Store | 1 | |
| 41. | Farfohnz | Nailed The Landing! / Dead Space 2 / Part 5 | 1 | |
| 42. | IRISH ANDROID | The Kool Aid Man - Dead Space ep15 | 1 | |
| 43. | DeeBeeHive - VOD Channel | Nicole, you're dumped. | Dee Plays - Dead Space 2 (4/4) | 1 | Let's Play |
| 44. | JamesH97 Gaming | Dead Space Let's Play #2 (Live Stream) | 1 | Let's Play |
| 45. | KhannonFTW | Eye Have A Bad Feeling About This - Dead Space 2 | 1 | |
| 46. | Ireland Deity | DEAD SPACE 2 Title Screen XBOX ONE X 11.01.23 | 1 | |
| 47. | The Failure Gamer | Dead Space 2 - Episode 4 - Isaac Clarke, Child Abuser | 1 | Show |
| 48. | The Failure Gamer | Dead Space 2 - Episode 23 - Ellie the Mournful | 1 | Show |
| 49. | Adam McDermott | BABIES! - Dead Space 2 Zealot Gameplay | 1 | |
| 50. | Adam McDermott | JAVELIN FOR YOUR FACE - Dead Space 2 Zealot Gameplay | 1 | Walkthrough |
| 51. | LuxuryClips | Playing Alien VS Predator In 2023 | 1 | |
