| 1. |  Markiplier | Dead Space 2 | Part 1 | WAKE UP DEAD | 1,266,851 | Let's Play |
| 2. | Nova | My Mom Plays / Hates Dead Space 2 | 1,100,852 | Let's Play |
| 3. | TobyGames | Let's Play Dead Space 2 - I'm Screwed - Part 1 | 900,783 | Let's Play |
| 4. | Markiplier | Dead Space 2 | Part 2 | PRETTY COLORS | 643,993 | Let's Play |
| 5. | Markiplier | Dead Space 2 | Part 3 | MINI BOSS | 586,168 | Let's Play |
| 6. |  The Yogscast | Yogscast - Simon Plays! - Dead Space 2 | 544,952 | Let's Play |
| 7. | Markiplier | Dead Space 2 | Part 4 | DARK ROOM OF HORROR | 511,982 | Let's Play |
| 8. | TobyGames | Let's Play Dead Space 2 - GRAVITY ARM - Part 2 | 476,015 | Let's Play |
| 9. | Markiplier | Dead Space 2 | Part 5 | TRAIN RIDE OF DOOM | 466,828 | Let's Play |
| 10. | Markiplier | Dead Space 2 | Part 6 | INTO THE CHURCH | 419,190 | Let's Play |
| 11. |  Sarazar | GAMEPLAY FAILS - Eure lustigsten Spielemomente [HD+] | 408,557 | Let's Play |
| 12. | Markiplier | Dead Space 2 | Part 7 | DID YOU KILL YOURSELF? | 402,206 | Let's Play |
| 13. | x5 CiNEMA | Dead Space 2 - The 'Reel' Movie (Game Movie) | 392,211 | Let's Play |
| 14. | TobyGames | Dead Space 2 - CAN'T SAVE! - Part 3 | 389,049 | Let's Play |
| 15. | Markiplier | Dead Space 2 | Part 8 | PERFECTLY NORMAL | 359,946 | Let's Play |
| 16. | TobyGames | Let's Play Dead Space 2 - Do NOT Make Out With Her - Part 4 | 352,451 | Let's Play |
| 17. | Markiplier | Dead Space 2 | Part 9 | I GOT THIS | 348,248 | Let's Play |
| 18. | Markiplier | Dead Space 2 | Part 10 | TOO BAD | 332,216 | Let's Play |
| 19. | Markiplier | Dead Space 2 | Part 11 | DARKNESS OF DARKNESS | 318,222 | Let's Play |
| 20. | TobyGames | Dead Space 2 - HUGE DEMON! - Part 5 | 311,306 | Let's Play |
| 21. |  RicharBetaCode | Dead Space 2 (Replay) | En Español | Capítulo 1 "Un mal despertar" | 300,802 | Let's Play |
| 22. | TobyGames | Dead Space 2 - JAVELIN - Part 6 | 298,476 | Let's Play |
| 23. | Markiplier | Dead Space 2 | Part 12 | EXPLOSIVE TUMORS | 297,725 | Let's Play |
| 24. | Markiplier | Dead Space 2 | Part 14 | THE ELEMENTARY | 296,370 | Let's Play |
| 25. | Markiplier | Dead Space 2 | Part 16 | MARKIPLIER RAGES | 285,803 | Let's Play |
| 26. | Markiplier | Dead Space 2 | Part 35 | MARKIPLIER DOMINATION | 285,412 | Let's Play |
| 27. | Markiplier | Dead Space 2 | Part 13 | HOW GREAT I AM | 278,769 | Let's Play |
| 28. | Markiplier | Dead Space 2 | Part 15 | ELEVATOR OF DOOM | 275,306 | Let's Play |
| 29. | Markiplier | Dead Space 2 | Part 17 | EASTER EGG | 264,116 | Let's Play |
| 30. | Markiplier | Dead Space 2 | Part 18 | I'M IN SPAAAAAAAAAAACE! | 260,203 | Let's Play |
| 31. | Markiplier | Dead Space 2 | Part 19 | ONSLAUGHT | 256,743 | Let's Play |
| 32. | TobyGames | Dead Space 2 - LAUNDRY DEMONS - Part 7 | 251,567 | Let's Play |
| 33. | Markiplier | Dead Space 2 | Part 23 | BACK TO THE ISHIMURA | 248,286 | Let's Play |
| 34. | Markiplier | Dead Space 2 | Part 20 | STILL CRAZY | 246,454 | Let's Play |
| 35. | Nova | Dead Space 2: Full Playthrough w/Nova Ep.1 - Enter Fear (Zealot Difficulty) | 245,365 | Let's Play |
| 36. | Sarazar | Let's Play Dead Space 2 #001 [Deutsch] [HD] | 235,671 | Let's Play |
| 37. | Markiplier | Dead Space 2 | Part 21 | ON THE TRAM | 234,949 | Let's Play |
| 38. | Markiplier | Dead Space 2 | Part 22 | PROFESSIONAL EXPERT | 234,922 | Let's Play |
| 39. | Markiplier | Dead Space 2 | Part 24 | DOWNWARD SPIRAL | 226,293 | Let's Play |
| 40. |  Lucky Salamander | Dead Space 2 - Parte 1: A Fuga Infernal de Isaac Clarke!!! [ PC - Playthrough ] | 219,760 | Let's Play |
| 41. | Markiplier | Dead Space 2 | Part 25 | FLAME FAIL | 218,186 | Let's Play |
| 42. | LtMkilla | Let's Play: Dead Space 2 - [Part 1/17] | 217,928 | Let's Play |
| 43. | Markiplier | Dead Space 2 | Part 33 | HE'S FOLLOWING ME! | 216,729 | Let's Play |
| 44. | Markiplier | Dead Space 2 | Part 29 | IT'S NICOLE! | 215,028 | Let's Play |
| 45. | LUANGAMEPLAY | LUAN GAMEPLAYS JOGANDO ALIEN ISOLEITION - MODO PESADELO | 214,125 | Let's Play |
| 46. | Markiplier | Dead Space 2 | Part 26 | THE BEST OF THE WORST | 212,627 | Let's Play |
| 47. | Markiplier | Dead Space 2 | Part 27 | STRING OF FAILURES | 212,586 | Let's Play |
| 48. | Markiplier | Dead Space 2 | Part 30 | ALL ALONE | 210,570 | Let's Play |
| 49. | Markiplier | Dead Space 2 | Part 34 | SPECTACULAR FAILURE | 209,683 | Let's Play |
| 50. | Markiplier | Dead Space 2 | Part 28 | MORTAL WOUND | 208,523 | Let's Play |
| 51. | TobyGames | Dead Space 2 - BOSS - Part 16 | 204,372 | Let's Play |
| 52. | TobyGames | Dead Space 2 - DEMON BABIES - Part 9 | 203,804 | Let's Play |
| 53. | TobyGames | Dead Space 2 - TRAIN - Part 8 | 203,625 | Let's Play |
| 54. | TobyGames | Dead Space 2 - WASTE DISPOSAL - Part 10 | 203,023 | Let's Play |
| 55. | PietSmiet | Let's Play Dead Space 2 #001 [Deutsch] [HD] - ... nur die Wurst hat 2 | 202,770 | Let's Play |
| 56. | Markiplier | Dead Space 2 | Part 32 | ANGER RISING | 202,243 | Let's Play |
| 57. | Markiplier | Dead Space 2 | Part 31 | ASKING FOR IT | 199,804 | Let's Play |
| 58. | LUANGAMEPLAY | LUAN GAMEPLAYS JOGANDO DEAD ESPACE - JOGO ASSUSTADOR CARA | 198,416 | Let's Play |
| 59. | TobyGames | Dead Space 2 - TIDEMANN - Part 11 | 195,337 | Let's Play |
| 60. | TobyGames | Dead Space 2 - BIRD DEMONS - Part 13 | 192,955 | Let's Play |
| 61. | TobyGames | Dead Space 2 - STAB YOURSELF - Part 12 | 192,758 | Let's Play |
| 62. | TobyGames | Dead Space 2 - FREEZER DEMONS - Part 14 | 188,390 | Let's Play |
| 63. | BlastphamousHD Gaming | ►►RUN LIKE A BI@!%!! - Dead Space 2 - Lets Play Part 1(Gameplay & Commentary) | 185,337 | Let's Play |
| 64. | TobyGames | Dead Space 2 - GIANT SPACE BOSS - Part 17 | 179,746 | Let's Play |
| 65. | Brock Baker | Bane Plays Dead Space 2 | 179,354 | Let's Play |
| 66. | TobyGames | Dead Space 2 - HOT CHICK - Part 20 | 174,505 | Let's Play |
| 67. | TobyGames | Dead Space 2 - FAT DEMONS - Part 18 | 173,742 | Let's Play |
| 68. | TobyGames | Dead Space 2 - ZERO GRAVITY - Part 15 | 172,147 | Let's Play |
| 69. | TobyGames | Dead Space 2 - SATELLITE - Part 28 | 169,413 | Let's Play |
| 70. | TobyGames | Dead Space 2 - MAIN FRAME - Part 27 | 160,113 | Let's Play |
| 71. | TobyGames | Dead Space 2 - INFANT DEMONS - Part 21 | 155,747 | Let's Play |
| 72. | LtMkilla | Let's Play: Dead Space 2 - Severed DLC [Complete] | 149,245 | Let's Play |
| 73. | TobyGames | Dead Space 2 - SECURITY SUIT - Part 23 | 148,307 | Let's Play |
| 74. | TobyGames | Dead Space 2 - BOSS FIGHT - Part 22 | 145,635 | Let's Play |
| 75. | RajmanGaming HD | Dead Space 2 'Playthrough PART 1 [PS3]' TRUE-HD QUALITY | 145,605 | Let's Play |
| 76. | TobyGames | Dead Space 2 - ELEVATOR DEMONS - Part 19 | 145,580 | Let's Play |
| 77. | TobyGames | Dead Space 2 - EYE NEEDLE - Part 62 | 142,013 | Let's Play |
| 78. | TobyGames | Dead Space 2 - HOTOGRAM - Part 26 | 140,656 | Let's Play |
| 79. | TobyGames | Dead Space 2 - ISHIMURA - Part 38 | 139,825 | Let's Play |
| 80. | loltyler1 | ALPHA DEAD SPACE 2 GAMEPLAY | 139,217 | Let's Play |
| 81. | TobyGames | Dead Space 2 - EXPLOSIVE BABIES - Part 25 | 137,749 | Let's Play |
| 82. | TobyGames | Dead Space 2 - CHUCK NORRIS DEMONS - Part 30 | 136,558 | Let's Play |
| 83. | Nova | Dead Space 2: Full Playthrough w/Nova Ep.2 - Play Doctor (Zealot Difficulty) | 136,537 | Let's Play |
| 84. |  Game Movie Land | DEAD SPACE 2 fr - FILM JEU COMPLET | 133,813 | Let's Play |
| 85. | TobyGames | Dead Space 2 - BIGGER ELEVATOR DEMONS - Part 24 | 133,717 | Let's Play |
| 86. | FiveGamesBR | Dead Space 2 - Final Boss + ENDING [HD] | 133,699 | Let's Play |
| 87. | TobyGames | Dead Space 2 - BURGLAR DEMONS - Part 33 | 133,336 | Let's Play |
| 88. | TobyGames | Dead Space 2 - CONTACT OWNAGE - Part 40 | 133,161 | Let's Play |
| 89. | LtMkilla | Let's Play: Dead Space 2 - [Part 2/17] | 132,279 | Let's Play |
| 90. | TobyGames | Dead Space 2 - SAVED BY THE ELLE - Part 67 | 129,395 | Let's Play |
| 91. | TobyGames | Toby Sucks at Dead Space 2 - DOOR DANCING DEMON - Part 39 | 128,915 | Let's Play |
| 92. | TobyGames | Dead Space 2 - I'M DEAD - Part 29 | 125,686 | Let's Play |
| 93. | TobyGames | Dead Space 2 - SUCK IT - Part 65 | 125,389 | Let's Play |
| 94. | TobyGames | Dead Space 2 - BULIMIC DEMONS - Part 31 | 124,173 | Let's Play |
| 95. | TobyGames | Dead Space 2 - DEMON LADY PARTS - Part 35 | 122,757 | Let's Play |
| 96. | TobyGames | Dead Space 2 - ITS A TRAP - Part 66 | 122,290 | Let's Play |
| 97. | HandOfBlood | Let's Play Dead Space 2 [HD|German|Blind] #01 Insekten-Invasion of Doom! | 121,521 | Let's Play |
| 98. | SuperBrioche - Let's Play - VOD Twitch | Dead Space 2 Let's Play en Facecam - Episode 1 : Retour en Enfer ! | 120,232 | Let's Play |
| 99. | JustKiddingGamer | Unco Chin Plays Dead Space 2 [Part 1] | 118,915 | Let's Play |
| 100. | Sarazar | Let's Play Dead Space 2 #002 [Deutsch] [HD] | 117,708 | Let's Play |
