| 1. |  G.O.T Games | First Time Reacting to ONE PIECE FILM RED | Ado "New Genesis" | Non Anime Fan! | 430 | |
| 2. | Lady Decade | The Lost Sega Genesis Console Add-On! - Gaming History Secrets | 261 | |
| 3. | Betty Horde Clinic | Mega Drive : Genesis 2 mini | 140 | |
| 4. | AntHazuki | Sega Mega Drive & Genesis Classics | Online Multiplayer is BROKEN! Gameplay With Commentary | 65 | |
| 5. | Matteusbeus - Retro Sega Dev | Halloween Update | Crypt of Dracula a new game for Sega Genesis & Mega Drive | 58 | Vlog |
| 6. | Lady Decade | The LOST Atari Genesis - Gaming History Secrets | 56 | |
| 7. | 128KB | SEGA Genesis Nintendo Switch Controller Review | 51 | |
| 8. | Kev Gaming XP | Sega Genesis Montage | 42 | |
| 9. | Matteusbeus - Retro Sega Dev | Technically Impressive Games for the Sega Genesis & Mega Drive - Power Rangers the Movie | 39 | |
| 10. | RetroBreak | Genesis Homebrew Review - A New Game Boy Shoot Em Up! | 38 | Review |
| 11. | Deadpan Flook | MTV's Beavis & Butthead ( Megadrive/Genesis, Game Gear, SNES) Preview Trailer | 33 | Preview |
| 12. | Kevin Muldoon | Sega Mega Drive Mini - Unboxing, Gameplay & Review (Sega Genesis Mini) | 27 | Review |
| 13. | EXTREME YouTube Gaming Channel | James Pond II: Codename RoboCod - Complete Soundtrack OST (Sega Mega Drive / Genesis) | 26 | Let's Play |
| 14. | Matteusbeus - Retro Sega Dev | Akira FMV on Sega Mega Drive & Genesis using SGDK? | 23 | |
| 15. | tribalkai | Shorikai Genesis Engine Vehicle Deck | MTG Commander Gameplay | tribalkai | 18 | |
| 16. | Right Sprite Retro Gaming UK | Life on Mars Genesis New Sega Megadrive / Genesis Games 2023 | 18 | |
| 17. | ACGamer | Goddess of Genesis S: Top 5 Units To reroll For | 14 | |
| 18. | Nash Hazzard | BUTTONS NOT WORKING? EASY FIX - SEGA MEGA DRIVE GENESIS CONTROLLER PAD | 13 | |
| 19. | Kevin Muldoon | Sega Mega Drive Mini & Genesis Mini Coming 19 September 2019 | 12 | |
| 20. | Retro Master | Sonic Neo Genesis Knuckles & Sonic playthrough | 12 | Let's Play |
| 21. | Ashley Eleanor | Genesis GV60 - The FIRST Genesis all electric SUV comes to the UK | 11 | |
| 22. | 80sretrogamer | (+18 only ) Divine Sealing Sega Mega Drive Genesis Review | 10 | Review |
| 23. | Video Game Therapy | 5 Sega Genesis/Mega Drive facts. | 9 | |
| 24. | TheDriver | Souten no Ken Re:Genesis (蒼天の拳 RE:GENESIS) Episode 1 Live Reaction/First Impressions | 7 | Show |
| 25. | Gaming Archive | 3 Ways To Connect a Sega Mega Drive To a Modern TV - Setup The MegaDrive TV Connection Sega Genesis | 6 | |
| 26. | Matteusbeus - Retro Sega Dev | Update on Crypt of Dracula a new game for Sega Genesis & Mega Drive | 6 | Vlog |
| 27. | 80sretrogamer | Joe and Mac Sega Mega Drive Genesis Review | 6 | Review |
| 28. | 128KB | Sega Genesis Nintendo Switch Controller Unboxing | 6 | |
| 29. | All Things Wrestling | Sega Mega Drive/Genesis Mk1 l Random Stuff I Brought Episode 3 #shorts #megadrive #genesis #sega | 6 | |
| 30. | 80sretrogamer | Ex Ranza Sega Mega Drive Genesis Review | 6 | Review |
| 31. | Matteusbeus - Retro Sega Dev | Matteusbeus plays Tänzer (Demo) for Sega Genesis & Mega Drive | 5 | Let's Play |
| 32. | 80sretrogamer | Capt'n Havoc Sega Mega Drive Genesis Review | 4 | Review |
| 33. | 80sretrogamer | Ex Mutants Sega Mega Drive Genesis Review | 4 | Review |
| 34. | thesegaguru | HOMEBREW PREVIEW - ARKAGIS - SEGA MEGADRIVE/GENESIS | 4 | Preview |
| 35. | 80sretrogamer | Bonkers Sega Mega Drive Genesis Review | 4 | Review |
| 36. | Golf Clips | Tiger Woods Round 3 Highlights Genesis Invitational 2023! | 3 | |
| 37. | Golf Clips | John Rahm Talks To The Press About His Win At The Genesis Invitational 2023! | 2 | |
| 38. | PotatoProWrestling | Sega Genesis Flashback Console Trailer Reaction | 2 | Preview |
| 39. | 80sretrogamer | Fido Dido Sega Mega Drive Genesis Review | 2 | Review |
| 40. | MikeyTheMachineGaming | Hook (Sega Genesis) - Longplay (Full Game) (Sega Genesis/MegaDrive) | 2 | |
| 41. | Idah09H | specifc speedrunning - the genesis project, parricide. 32.58 | 2 | |
| 42. | 80sretrogamer | Socket Sega Mega Drive Genesis Review | 2 | Review |
| 43. | 80sretrogamer | Fire Mustang Sega Mega Drive Genesis Review | 2 | Review |
| 44. | 80sretrogamer | Mcdonalds TresureLand Adventures Sega Mega Drive Genesis Review | 2 | Review |
| 45. | 80sretrogamer | Lotus 2 Sega Mega Drive Genesis Review | 2 | Review |
| 46. | 80sretrogamer | Bubsy Sega Mega Drive Genesis Review | 1 | Review |
| 47. | MikeyTheMachineGaming | Mortal Kombat (Genesis) All Fatalities (Sega Genesis/Megadrive) | 1 | |
| 48. | Golf Clips | John Rahm Winning Highlights Genesis Invitational 2023! | 1 | |
| 49. | KruGames | Goddess of Genesis Gameplay Walkthrough #1 (Android, IOS) | 1 | Walkthrough |
| 50. | 80sretrogamer | Lotus Turbo Challenge Sega Mega Drive Genesis Review | 1 | Review |
| 51. | SkyTrap Al ASMR | ASMR Whisper Genesis/Solo Genesis Vinyl and CD collections. | 1 | |
| 52. | Craigy Boy Gaming | Genesis Does! Do You Remember This SEGA Genesis TV Commercial? | 1 | |
| 53. | Golf Clips | Xander Schauffele Slam Dunks His Ball Into The Hole For Eagle On 17 At Genesis Invitational 2023! | 1 | |
| 54. | 80sretrogamer | Granade Sega Mega Drive Genesis Review | 1 | Review |
| 55. | 80sretrogamer | Dangerous Seeds Sega Mega Drive Genesis Review | 1 | Review |
| 56. | AntHazuki | Sega Mega Drive & Genesis Classics | Analysis: All 50 Games, Features, Trophies & Challenges! | 1 | |
| 57. | Mega Drive Sound | Genesis - Another Record (Mega Drive Cover) | 1 | |
| 58. | VGCW Network | WVGCW GENESIS S5E16: Final: 10: Match 2/3 Falls Genesis V Final: Djeeta Vs. Aerith Gainsborough | 1 | |
| 59. | Yester Quest | The Mega Drive / Genesis Mysteries #4 | put your Sega games knowledge to the test! | 1 | Review |
| 60. | 80sretrogamer | Berenstain Bears Camping Adventures Sega Mega Drive Genesis Review | 1 | Review |
| 61. | Craigy Boy Gaming | Mecha Jackson! - Michael Jackson's Moonwalker - SEGA Mega Drive /Genesis - Almost Full Playthrough | 1 | |
