| 1. |  derangedband | Portal Lab Rat | 719,563 | |
| 2. |  Klei Entertainment | Lab Rat - 4K Gameplay Trailer [Coming Soon!] | 627,055 | |
| 3. | Klei Entertainment | Lab Rat - Official Launch Trailer [4k] | 363,253 | |
| 4. |  Disney Jr. | SuperKitties Stop Lab Rat! | SuperKitties | @disneyjunior | 84,077 | |
| 5. |  Wilbur Soot Twitch Vods - Unofficial | 'Minecraft 100 Player Lab Rat Experiment' Wilbur Soot VOD | 36,466 | |
| 6. | IGN | Lab Rat - Official Reveal Trailer | gamescom 2020 | 28,617 | Preview |
| 7. | Tommy's Puppet Lab | Making Fabrice the Lab Rat! (Original Character) | 27,804 | |
| 8. | GiantGrantGames Archives | Twitch Chat Picks My Swarm - Lab Rat & Back in the Saddle | 21,486 | |
| 9. | Ima_Rainbow | Two Ways to Become a Lab Rat? (Yeeps: Hide & Seek) Requires Dedication | 17,181 | |
| 10. | gia | Pokemon GSC - Crystal - Celebi Glitch - Shiny Celebi | 9,678 | |
| 11. | Marlongamingnation | Veteran Game Developer Talks New Game Lab Rat | PS5 and Xbox Series X Interview | 6,431 | |
| 12. | indeed not funny | FNF Vs Mouse: Labrat Scene 2 Restored with Labrat's Voice | 6,326 | |
| 13. |  Staszek iGRAszkowski | Lab Rat PL #1 | Portal w wersji indie, satyryczny acz niegłupi | 6,153 | |
| 14. | GwenFreyTheTA | Lab Rat - Official Trailer | 6,030 | |
| 15. |  Carrot Helper - 100% Walkthroughs | No Commentary | Lab Rat - Full Game Walkthrough (No Commentary) - 100% Achievements | 5,930 | |
| 16. | 100% Guides | Escape Academy Lab Rat Walkthrough | 5,589 | Walkthrough |
| 17. | gia | Pokemon GSC - Crystal - Celebi Glitch - Shiny Celebi 2 | 3,901 | |
| 18. | ID@Xbox | Lab Rat Official Trailer | 3,253 | |
| 19. | lil indigestion | Writer Reacts to Portal 'Lab Rat' web comic | 2,672 | |
| 20. | Unreal Engine | Lab Rat | Game Profile | Unreal Engine | 2,527 | |
| 21. |  INZA GAMING | FNF LabRat || rainbow friends roblox || #fnf#labrat #rainbowfriends | 2,199 | |
| 22. | Cutiefox | Lab Rat | ASMR Roleplay | F4F | Post Apocalyptic Cleanup | Resurrected Lab Rat Listener | Adopted | 2,094 | |
| 23. | GwenFreyTheTA | Lab Rat - The Dev Teaser Trailer | 1,963 | |
| 24. | GameTrailers | Lab Rat - Official Trailer | ID@Xbox | 1,815 | Preview |
| 25. | GwenFreyTheTA | Lab Rat - Official Reveal Trailer | 1,683 | |
| 26. |  Throneful | Lab Rat Gameplay (PC UHD) [4K60FPS] | 1,165 | |
| 27. | Tesseption | VS LAB RAT MICKY MOUSE! | FULL DEMO *REACTION* | FNF Mod W/Tess! | 1,010 | |
| 28. |  Tugay Kocyigit | LAB RAT Gameplay FULL GAME - No Commentary - Part 1 | 1,006 | |
| 29. | Kitty360 | How Fast do People Recognize There is a Lab Rat #shorts #yeeps #labrat | 978 | |
| 30. | Kitty360 | Yeeps Redstone Update!? (Lab Rat) | 945 | |
| 31. | Game Guides Channel | Escape Academy Lab Rat Solution | 822 | |
| 32. |  PSTHC | Les Schtroumpfs Mission Malfeuille - Lab Rat Trophy Guide | Trophée Laborantin | 767 | |
| 33. |  ShinkuKaioken | NBA STREET: HomeCourt - Lab Rat Produce - Lab Rat Funk | 633 | |
| 34. | Joe Plays Puzzle Games | Lab Rat - Part 1: M'Lady | 567 | |
| 35. | Kitty360 | Yeeps Bonus Update!? (Lab Rat) | 528 | |
| 36. | scgamesvr | The Yeeps Survival Update! (Lab Rat Version) | 519 | |
| 37. | Visual Novelty | malViolence [FT] All Eyes On YOU, Lab Rat! | 488 | |
| 38. | Stay Frosty | #SHORTS GTA ONLINE - LAB RAT. | 472 | |
| 39. | OofsGoofs | Yeeps: Hide And Seek just got an Ocean Update! (LAB RAT TESTING) | 437 | |
| 40. |  Active Wazza | FALLOUT LONDON Walkthrough Gameplay: LAB RAT #letsplay #gaming #falloutlondon | 422 | |
| 41. | DROIDZ | SuperKitties Kittydale Quests | Lab Rat Level 1-4 (SuperKitties Games) | 404 | |
| 42. | Gabe and the Goat | Lab Rat - Part 2 - Tier 1 Test Plan - Full Walkthrough | 392 | |
| 43. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 1: Turning | 380 | |
| 44. | boooka | Lab Rat Demo Full Walkthrough | 331 | Walkthrough |
| 45. | Gabe and the Goat | Lab Rat - Part 3 - Tier 2 Test Plan - Full Walkthrough | 306 | |
| 46. | angryponcho | Let's Play Pokemon TCG | Pt. 10 - A Wild Lab Rat Appeared! | 301 | |
| 47. | INeedGlitch2Win | We have GladoS at home | Lab Rat: Phase 0 ( All tests complete ) | Glitch Plays | 286 | |
| 48. | ZeroVanPlay | Новелла про крысочеловека 「Lab Rat 」 | 268 | |
| 49. |  Juggernaut | Let's Play Fallout London #1 (Lab Rat) | 252 | |
| 50. | Hanahime Mei / ハナヒメ メイ【bondEN】 | IM A SMART LITTLE LAB RAT!【Hanahime Mei | bondEN】 | 240 | |
| 51. | RonEmpire | Let's Play - Lab Rat - You Are the Test Subject Experiment - Dark Humor Puzzle Game - Full Gameplay | 223 | |
| 52. | IGS | Lab Rat Demo | PC Gameplay | 217 | |
| 53. | DROIDZ | SuperKitties Kittydale Quests | Save Purple Flowers From Lab Rat! (SuperKitties Games) | 216 | |
| 54. |  ぬどん | 「Lab Rat」体験版をプレイ！ | 207 | |
| 55. | Slipguides | Crysis 2 SuperSoldier Difficulty Guide: Lab Rat [1/2] | 198 | Guide |
| 56. | Joe Plays Puzzle Games | Lab Rat - Part 10 [Finale]: Boss Fight | 188 | |
| 57. |  Fase De Mantenimiento | LabRat - Prototipo — Videoreseña | 185 | |
| 58. | Slipguides | Crysis 2 SuperSoldier Difficulty Guide: Lab Rat [2/2] | 178 | Guide |
| 59. | Viswanadh | Crysis - 2 - Part - 5 Gameplay Mission : (Lab Rat) Infiltrate warehouse | 168 | |
| 60. | Joe Plays Puzzle Games | Lab Rat - Part 3: Alan's Games | 164 | |
| 61. | Joe Plays Puzzle Games | Lab Rat - Part 2: Paint | 163 | |
| 62. | Anthony Collins | SuperKitties The Wraft of Lab Rat PS2 Opening Logos | 159 | Vlog |
| 63. | Joe Plays Puzzle Games | Lab Rat - Part 8: Combat Simulator | 146 | |
| 64. | Warp Door | Lab Rat (Demo Playthrough) Move objects, divert lasers, and manipulate electricity to solve puzzles! | 141 | Let's Play |
| 65. | Joe Plays Puzzle Games | Lab Rat - Part 9: Platformer | 139 | |
| 66. | Joe Plays Puzzle Games | Lab Rat - Part 6: Noir | 131 | |
| 67. | JackTheFallout | We Broke SCP-096 And Got Hunted By SCP-049 | SCP Lab Rat Multiplayer Beta #2.☢️ | 130 | |
| 68. | Joe Plays Puzzle Games | Lab Rat - Part 7: Colourful Floor | 128 | |
| 69. | Gabe and the Goat | Lab Rat - Part 1 - Mandatory Employee Training - Full Walkthrough | 126 | |
| 70. | MODGAMINYT | Fallout London Is Here! Ep 1 Lab Rat! | 123 | |
| 71. | Joe Plays Puzzle Games | Lab Rat - Part 4: Bottlenecks | 122 | |
| 72. | Joe Plays Puzzle Games | Lab Rat - Part 5: Tubes | 121 | |
| 73. | CODELYOKOSTUDIOS2003 | Lab Rat\Bragging Rights Combination | 119 | |
| 74. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 3: Synchronize | 118 | |
| 75. | AllGamesWorldHd | Lab Rat Gameplay - Full Beta/Demo | 105 | |
| 76. | Tugay Kocyigit | LAB RAT Gameplay FULL GAME - No Commentary - Part 2 | 104 | |
| 77. | MaYHeM _Ex | Waltz realises about Aiden, his old lab rat!!! #dyinglight2 #mayhem_ex | 100 | |
| 78. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 17 [Finale]: Discipline | 98 | |
| 79. | CSG | 1080p! CRYSIS 2! Lab Rat! GAMEPLAY! WALKTHROUGH! PLAYTHROUGH! Full HD! | 96 | Walkthrough |
| 80. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 8: Cheese | 95 | |
| 81. |  Jin Kong | iPC의 크라이시스 2 : #5 Lab Rat | 93 | |
| 82. | Gabe and the Goat | Lab Rat - Part 4 - Tier 3 Test Plan - Full Walkthrough | 93 | |
| 83. | Trailers Irmãos Piologo | Lab Rat - Trailer | 92 | Preview |
| 84. |  Le Avventure Di Frankie | IL FINALE CHE NON TI ASPETTI!! - Minecraft Lab Rat #3 | 91 | |
| 85. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 2: Delay | 91 | |
| 86. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 10: Split Up | 89 | |
| 87. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 4: Triple Merge | 85 | |
| 88. | Virtute | Lab Rat Playtest | Full Beta | No Commentary Walkthrough | 83 | Walkthrough |
| 89. | LilArrin | Starcraft HoTS Campaign - Lab Rat (Brutal, All Achievements + Bonus) | 82 | |
| 90. |  LatestDave | I'm A Lab Rat Of An Artificial Intelligent | SUBJECT | Let's Play | 75 | Let's Play |
| 91. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 11: Chaos | 74 | |
| 92. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 6: Explosive | 73 | |
| 93. | Le Avventure Di Frankie | COSTRETTO A DISTRUGGERE LA MAPPA!! - Minecraft Lab Rat #2 | 72 | |
| 94. | ShinkuKaioken | NBA STREET: HomeCourt - Lab Rat Produce - Lab Rat Funk (On Court) | 72 | |
| 95. | Good Shark | Lab Rat Location 7 - Abiotic Factor | 70 | Guide |
| 96. | Gamer Linear | Lab Rat Gameplay PC | 70 | |
| 97. | Gabe and the Goat | Lab Rat - Part 6 - M Labs and Control Room Floors - Full Walkthrough | 67 | |
| 98. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 7: Cross Over | 66 | |
| 99. | AllFunNGamez | Klei Publishing New Game - Lab Rat - Lab Rat Trailer Review - Klei Lab Rat Game | 65 | Review |
| 100. | Joe Plays Puzzle Games | Lab Rat-ional Thinking + Flying Crowbar Factory Simulator 2022 - Part 5: Phase Through | 63 | |
