| 1. |  Jester | siri captured me... i need help | 27,000 | |
| 2. | Calvin Romeyn | Galactic Battles - A Crossover Fan Film Featuring: Star Wars, Star Trek, Halo & Mass Effect | 25,011 | |
| 3. | Mei Yu | Draw Disney Princesses as HOT GUYS | ART CHALLENGE! | Mei Yu Reimagine Challenge Genderbend | 9,124 | |
| 4. | EckhartsLadder | Could the Halo Galaxy Survive a Reaper Invasion? Mass Effect vs Halo: Galactic Versus | 8,683 | |
| 5. | EckhartsLadder | Halo vs Mass Effect in ALL OUT WAR -- Who Would Win? | Galactic Versus | 3,127 | |
| 6. | SomeOrdinaryGamers | My Family Found Rule 34 Of Me... | 3,000 | |
| 7. | AtinPiano | Mass Effect Trilogy Medley (Piano Cover) | 2,586 | Vlog |
| 8. | EckhartsLadder | UNSC Infinity with Escort Fleet vs. Alliance Fleet (Mass Effect) | Fleet Versus | 1,999 | |
| 9. | EckhartsLadder | Which Sci-Fi Faction has the MOST PLOT ARMOR? | Halo, Mass Effect & Star Wars Lore | 1,763 | |
| 10. | EckhartsLadder | BRUTE (Halo) vs. KROGAN (Mass Effect) | Who Would Win? | 1,644 | |
| 11. | Gaming Ambience | Mass Effect - Main Title Screen (1 Hour of Music) | 1,386 | |
| 12. | EckhartsLadder | Could the SYSTEMS ALLIANCE destroy the DEATH STAR II (and its fleet)? | Mass Effect vs Star Wars | 1,230 | |
| 13. | Kevduit | Being a PSYCHOPATH in Mass Effect | 1,218 | |
| 14. | EckhartsLadder | Which Sci-Fi Faction has the BEST AI? | Halo, Star Wars, Mass Effect, the Culture | 1,192 | |
| 15. | The Templin Institute | The Strangest Choice in Mass Effect | 1,158 | |
| 16. | The Templin Institute | The Post-Reaper War Reimagined | Mass Effect | 958 | |
| 17. | Gaming Ambience | Mass Effect - Noveria: Port Hanshan Plaza (1 Hour of Music & Ambience) | 900 | |
| 18. | The Templin Institute | Systems Alliance | Mass Effect | 882 | |
| 19. | EckhartsLadder | Which Sci-Fi Faction has the BEST HOME FLEET? | Factions Compared: Halo, Mass Effect, Star Wars | 854 | |
| 20. | Hacksmith Industries | Testing a Real Mass Effect Plasma Rifle | 827 | |
| 21. | EckhartsLadder | Dreadnoughts of the Mass Effect Universe | Mass Effect Lore Explained | 809 | |
| 22. | FRIENDLY Ai | Mass Effect 4 Trailer In The Works | 801 | Preview |
| 23. | The Templin Institute | Where Does Mass Effect Go From Here? | A Pitch For The Future Of The Universe | 783 | |
| 24. | smudboy | Mass Effect Trilogy Remaster coming in 2021 | 754 | Vlog |
| 25. | WoolieVersus | My Name Is Red Shepard | Mass Effect (1) | 606 | |
| 26. | The Templin Institute | Cerberus | Mass Effect | 557 | |
| 27. | EckhartsLadder | How the CITADEL FLEET defeated SOVEREIGN | Mass Effect Battle Breakdown | 552 | |
| 28. | WoolieVersus | How Mass Effect Should Have Ended | Castle Super Beast Clips | 515 | Show |
| 29. | The Templin Institute | Turian Hierarchy | Mass Effect | 510 | |
| 30. | ENDYMIONtv | Mass Effect 4 Shepard Returns | 480 | |
| 31. | Егор Клёнов | Сюжет всех частей Mass Effect в одном видео | 477 | |
| 32. | The Templin Institute | Systems Alliance Navy | Mass Effect | 473 | |
| 33. | Pat Stares At | Pat Stares At Mass Effect 1 Legendary Edition! (Part 1) | 472 | |
| 34. | Whimsy Psyche | (First Playthrough) I'm OBSESSED! 😍 | Mass Effect Legendary Edition - Ep.1 | Let's Play [Veteran] | 467 | Let's Play |
| 35. | MojoPlays | 10 Hardest Decisions in the Mass Effect Series | 466 | |
| 36. | VaporTheGamer | Vapor Reacts #1116 | DON'T HUG ME I'M SCARED ORIGINAL SONG "Father's Day" by CG5 REACTION!! | 463 | |
| 37. | Cannot be Tamed | The original Mass Effect ending was fine, actually | Cannot be Tamed | 457 | |
| 38. | ChristopherOdd | Mr. Odd - Let's Play Mass Effect 1 - Part 1 - Odd Shepard, Mass Effect's Only Hope | 451 | Let's Play |
| 39. | The Templin Institute | Quarian Migrant Fleet | Mass Effect | 405 | |
| 40. | WoolieVersus | Castle Super Beast: Backwards Rationale Reloading Mass Effect | 378 | Show |
| 41. | The Templin Institute | Krogan Clans | Mass Effect | 371 | |
| 42. | Guest | Mass effect reference in the New Halo Show | Shepard & Skyllian Verge | 368 | |
| 43. | TetraNinja | I Am Alive Walkthrough - Part 1 Prologue Let's Play PS3 XBOX 360 (Gameplay / Commentary) | 365 | Walkthrough |
| 44. | Whimsy Psyche | [COSPLAY] This is so EPIC! | Mass Effect Legendary Edition - Ep.14 (ENDING) | Let's Play [Veteran] | 353 | Let's Play |
| 45. | The Templin Institute | M35 Mako Infantry Fighting Vehicle | Mass Effect | 345 | |
| 46. | ChristopherOdd | 🔴 LIVE AND LEGENDARY // Mass Effect 1 Legendary Edition // Part 1 | 336 | |
| 47. | WoolieVersus | Yo Saren! You Should [Renegade Option] Yourself... Now! | Mass Effect (61 FINAL) | 330 | |
| 48. | MojoPlays | 10 Biggest Changes in Mass Effect Legendary Edition | 326 | Let's Play |
| 49. | smudboy | E3's Mass Effect 4 Teaser Trailer (of Trees) | 316 | |
| 50. | Егор Клёнов | Эффект массы ностальгии. Обзор ремастера Mass Effect | 302 | |
| 51. | WoolieVersus | Scuttlebutt: Meet The Crew | Mass Effect (13) | 294 | |
| 52. | WoolieVersus | Redder Than Red | Mass Effect (EXTRA) | 290 | |
| 53. | WoolieVersus | Red Shepard: Resurrect The Reapers For The Nut | Mass Effect (8) | 285 | |
| 54. | VGS - Video Game Sophistry | NEW MASS EFFECT Game Trailer Analysis // Shepard’s Story Continues? | 282 | Preview |
| 55. | WoolieVersus | So Measurehead And An Asari Walk Into A Bar… | Mass Effect (18) | 281 | |
| 56. | WoolieVersus | (Sigh in Renegade) | Mass Effect (9) | 279 | |
| 57. | The Templin Institute | Illium | Mass Effect | 274 | |
| 58. | WoolieVersus | Treat Element Zero Like A Stand Arrow For Orphans | Mass Effect (3) | 272 | |
| 59. | ChristopherOdd | Mr. Odd - Let's Play Mass Effect 1 - Part 2 - Nihlus Wants Me As A Spectre? | 268 | Let's Play |
| 60. | gamermd83 | Kiss, Marry, Kill: Video Games Style! | 266 | |
| 61. | Whimsy Psyche | Call me a Spectre now 😏 | Mass Effect Legendary Edition - Ep.2 | Let's Play [Veteran] | 266 | Let's Play |
| 62. | smudboy | Ode to Mirand(ass) | 266 | |
| 63. | WoolieVersus | Make A Right Turn Into The Coolest Room | Mass Effect (4) | 264 | |
| 64. | WoolieVersus | Choose | Mass Effect (55) | 261 | |
| 65. | Welonz | Commander Welonz Reporting for Duty - Let's Play Mass Effect Legendary Edition Part 1 [PC Gameplay] | 257 | Let's Play |
| 66. | WoolieVersus | That Clump of Tentacles is a Person, Red | Mass Effect (6) | 254 | |
| 67. | Gaming Ambience | Mass Effect - Citadel: C-SEC Atrium (1 Hour of Music) | 251 | |
| 68. | WoolieVersus | "Daddy" Is Not a Rank, Sir | Mass Effect (2) | 250 | |
| 69. | rizzler | Mass Effect 4 : What We Want | Gameplay Possibilities | 245 | |
| 70. | Whimsy Psyche | Did I mess up in Virmire?! 😭 | Mass Effect Legendary Edition - Ep.13 | Let's Play [Veteran] | 238 | Let's Play |
| 71. | Gaming Ambience | Mass Effect - The Citadel: Upper Wards (1 Hour of Music) | 237 | |
| 72. | ChristopherOdd | Mr. Odd - Let's Play Mass Effect 1 - Part 64 - Mass Effect Ending | 221 | Let's Play |
| 73. | WoolieVersus | [Graze Him] | Mass Effect (52) | 220 | |
| 74. | WoolieVersus | Council Gonna Council | Mass Effect (5) | 220 | |
| 75. | gamermd83 | The Next Mass Effect? | 217 | |
| 76. | Gaming Ambience | Mass Effect - Ilos: Archives (1 Hour of Music) | 211 | |
| 77. | WoolieVersus | SALVAGE MODE ENGAGED | Mass Effect (34) | 209 | |
| 78. | WoolieVersus | Establishing Headshot | Mass Effect (7) | 208 | |
| 79. | WoolieVersus | "Put The Krogan Statue In a Museum!" | Mass Effect (11) | 207 | |
| 80. | The Templin Institute | Noveria | Mass Effect | 206 | |
| 81. | WoolieVersus | The First Skill Test | Mass Effect (16) | 203 | |
| 82. | ChristopherOdd | Mr. Odd - Let's Play Mass Effect 1 - Part 20 - Ashley is a Racist | 201 | Let's Play |
| 83. | WoolieVersus | The CASH System: Cover, Abilities, Shoot, Heal | Mass Effect (17) | 197 | |
| 84. | gamermd83 | Mass Effect: Which Alien Race Are You Quiz | 197 | |
| 85. | WoolieVersus | Shepard Loves The Press | Mass Effect (19) | 195 | |
| 86. | Gaming Ambience | Mass Effect - Galaxy Map Theme (1 Hour of Music) [4K] | 194 | |
| 87. | smudboy | RE: Mass Effect Legendary Edition Has HUGE Changes | 193 | |
| 88. | smudboy | Analysis of Mass Effect 5 Teaser Trailer 2020 | 190 | Preview |
| 89. | GamesGoneNuts | Mass Effect - Intro | 189 | |
| 90. | Whimsy Psyche | Love is in the air 💙 | Mass Effect Legendary Edition - Ep.6 | Let's Play [Veteran] | 186 | Let's Play |
| 91. | ENDYMIONtv | Mass Effect 4 Theories & Evidence! | 185 | |
| 92. | rizzler | Mod Library : Mass Effect HD Retexture/Remake | 183 | |
| 93. | ENDYMIONtv | Mass Effect 4 The Kett Invasion | 183 | |
| 94. | Whimsy Psyche | Forced Retirement for Cpt Anderson 😤 | Mass Effect Legendary Edition - Ep.3 | Let's Play [Veteran] | 181 | Let's Play |
| 95. | Whimsy Psyche | We found LIARA! | Mass Effect Legendary Edition - Ep.4 | Let's Play [Veteran] | 179 | Let's Play |
| 96. | WoolieVersus | Spaghetti, All Over The Normandy | Mass Effect (37) | 177 | |
| 97. | WoolieVersus | THIS IS MY KILL, GARRUS | Mass Effect (44) | 174 | |
| 98. | WoolieVersus | BATARIANS | Mass Effect (50) | 172 | |
| 99. | Pat Stares At | Pat Stares At Mass Effect 1 Legendary Edition! (Part 2) | 171 | |
| 100. | WoolieVersus | [ZOOM OUT] | Mass Effect (12) | 171 | |
