| 1. |  Kevduit | Being a PSYCHOPATH in Mass Effect 3 | 1,464,553 | |
| 2. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 1 Opening Prologue and Eden Prime Let's Play | 1,374,860 | Let's Play |
| 3. | AtinPiano | An End, Once And For All - Mass Effect 3 (Piano Cover) [Best Ending] | 1,058,296 | |
| 4. | TetraNinja | Mass Effect 3 Walkthrough - Part 1 Reaper Invasion PS3 XBOX 360 PC (Gameplay / Commentary) | 817,348 | Walkthrough |
| 5. | VGS - Video Game Sophistry | Mass Effect 3- Javik Talks to the Prothean VI | 756,513 | |
| 6. | Raycevick | A "Mature" Sports Game | 742,754 | |
| 7. | TetraNinja | Mass Effect 3 Walkthrough - Extended Cut DLC Synthesis Ending Let's Play XBOX PS3 PC | 724,908 | Walkthrough |
| 8. | TetraNinja | Mass Effect 3 Walkthrough - Extended Cut DLC Destroy Ending Let's Play XBOX PS3 PC | 666,131 | Walkthrough |
| 9. | VGS - Video Game Sophistry | Mass Effect 3: Citadel DLC: MY HAMSTER! NOOOOO! | 594,029 | |
| 10. | AtinPiano | I Was Lost Without You [Extended] - Mass Effect 3 (Piano Cover) | 588,816 | |
| 11. | TetraNinja | Mass Effect 3 Walkthrough - Extended Cut DLC Control Ending Let's Play XBOX PS3 PC | 578,981 | Walkthrough |
| 12. | VGS - Video Game Sophistry | Mass Effect 3- Javik Loves Liara, Tali.....and Fish | 471,536 | |
| 13. | smudboy | ME3: The Top 20 Questionable Things Part 1 | 444,505 | |
| 14. | Genol3oost | Mass Effect 3 | Thomas Bergersen - Remember Me | 434,194 | |
| 15. | AtinPiano | Leaving Earth - Mass Effect 3 (Piano Cover) | 387,925 | |
| 16. | TetraNinja | Mass Effect 3 Walkthrough - Extended Cut DLC Hidden Refusal Ending Let's Play XBOX PS3 PC | 353,300 | Walkthrough |
| 17. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 2 Geth, Bombs and Prothean Beacon Let's Play | 349,021 | Let's Play |
| 18. | Chasing Skyler | TITAN TV MAN GETS TORTURED AND INFECTED💀 | skibidi toilet 77 (full episode) | 348,387 | |
| 19. | AtinPiano | An End, Once and For All - Mass Effect 3 (Piano Cover) [Beginner] | 336,653 | |
| 20. | VGS - Video Game Sophistry | Mass Effect 3- Javik the Prothean 50'000 Years Ago. | 316,840 | |
| 21. | VGS - Video Game Sophistry | Mass Effect 3: Citadel DLC - Don't Call Wrex Fat...or He'll DANCE! | 281,999 | |
| 22. | Gaming Ambience | Mass Effect 3 - Normandy: Captains Cabin (1 Hour of Ambience) | 278,072 | |
| 23. | Gaming Ambience | Mass Effect 3 - The Catalyst (1 Hour of Music) | 261,921 | |
| 24. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 3 Normandy and the Citadel Let's Play | 255,937 | Let's Play |
| 25. | VGS - Video Game Sophistry | Mass Effect 3: Javik The Protheans First Encounter | 255,749 | |
| 26. | TetraNinja | Mass Effect 3 Walkthrough - Part 2 Mars Archive Part 65 Fighter Escape PS3 XBOX 360 PC | 251,265 | Walkthrough |
| 27. | AtinPiano | A Future For The Krogan | Reignite - Mass Effect 3 (Piano Cover) | 242,426 | |
| 28. | Gaming Ambience | Mass Effect 3 - Cronos Station: The Illusive Man's Room (1 Hour of Music) | 239,074 | |
| 29. | Gaming Ambience | Mass Effect 3 - Mars (1 Hour of Music) | 230,641 | |
| 30. | DanQ8000 | Mass Effect 3 - Extended Cut DLC (All Cutscenes, Best Ending) | DanQ8000 | 227,916 | |
| 31. | The Templin Institute | Geth Consensus | Mass Effect | 226,088 | |
| 32. | Gaming Ambience | Mass Effect 3 - Citadel Embassies (1 Hour of Music & Ambience) | 217,641 | |
| 33. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 4 Wrex and Save the Doctor Let's Play | 216,810 | Let's Play |
| 34. | LittleVMills | Mass Effect 3 Theme Epic Rock Cover (Little V) | 213,291 | |
| 35. | TetraNinja | Mass Effect 3 Walkthrough - Part 3 Tram Sentry Part 65 Fighter Escape (Gameplay / Commentary) | 190,017 | Walkthrough |
| 36. | gamermd83 | The MD Trailer of Awesomeness | 188,769 | Preview |
| 37. | ChristopherOdd | Mr. Odd - Let's Play Mass Effect 3 [BLIND] - Part 1 - Earth. Odd Shepard. Earth. | 182,786 | Let's Play |
| 38. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 5 FIST-ful of Wrex and Save Tali Let's Play | 171,511 | Let's Play |
| 39. | Skill Games | Mass Effect 3 Walkthrough Part 1 PS3 | 171,169 | Walkthrough |
| 40. | VGS - Video Game Sophistry | Mass Effect 3- I AM URDNOT WREX, AND THIS IS MY PLANET! | 170,829 | |
| 41. | Gaming Ambience | Mass Effect 3 - Normandy: Galaxy Map (1 Hour of Music & Ambience) | 164,322 | |
| 42. | VGS - Video Game Sophistry | Mass Effect 3- Javik Mind Melds on Thessia | 163,379 | |
| 43. | TetraNinja | Mass Effect 3 Walkthrough - Part 4 Illusive Man PS3 XBOX 360 PC (Gameplay / Commentary) | 162,221 | Walkthrough |
| 44. | Genol3oost | Mass Effect 3 | Two Steps From Hell - Nero | 162,107 | |
| 45. | Gaming Ambience | Mass Effect 3 - Main Title Screen (1 Hour of Music) | 161,075 | |
| 46. | VGS - Video Game Sophistry | Mass Effect 3: Citadel- Javik, STOP MAKING FUN OF ME! | 161,035 | |
| 47. | VGS - Video Game Sophistry | Mass Effect 3- Joker Finds Out About His Family | 160,747 | |
| 48. | VGS - Video Game Sophistry | Mass Effect 3- Legion is Ashamed | 155,897 | |
| 49. | TetraNinja | Mass Effect 3 Walkthrough - Part 6 Citadel Council PS3 XBOX 360 PC (Gameplay / Commentary) | 155,191 | Walkthrough |
| 50. | TetraNinja | Mass Effect 3 Walkthrough - Part 5 Dr. Eva PS3 XBOX 360 PC (Gameplay / Commentary) | 153,227 | Walkthrough |
| 51. | The Templin Institute | The Citadel | Mass Effect | 151,784 | |
| 52. | TetraNinja | Mass Effect 3 Walkthrough - Leviathan DLC Part 1 Reaper Killer Let's Play XBOX PS3 PC | 150,211 | Walkthrough |
| 53. | Gaming Ambience | Mass Effect 3 - Leaving Earth (1 Hour of Feels) | 150,038 | |
| 54. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 6 I'm a Spectre Bitch! Let's Play | 147,964 | Let's Play |
| 55. | VGS - Video Game Sophistry | Mass Effect 3: Citadel DLC: Introducing......URDNOT WREX! | 144,953 | |
| 56. | VGS - Video Game Sophistry | Mass Effect 3- Javik Reveals Asari Past! | 143,364 | |
| 57. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 7 Citadel Asari Consort Let's Play | 139,148 | Let's Play |
| 58. | TetraNinja | Mass Effect 3 Walkthrough - Citadel DLC Part 1 Random Acts of Violence Gameplay Commentary | 138,006 | Walkthrough |
| 59. | smudboy | ME3: The Top 20 Questionable Things Part 2 | 136,252 | |
| 60. | TetraNinja | Mass Effect 3 Walkthrough - From Ashes DLC Part 1 Prothean Artifact Let's Play (Gameplay/Commentary) | 134,918 | Walkthrough |
| 61. | Gaming Ambience | Mass Effect 3 - Dreams (1 Hour of Music) | 132,401 | |
| 62. | VGS - Video Game Sophistry | Mass Effect 3- Javik is Not Happy About Legion | 131,224 | |
| 63. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 10 MAKO = Frustration Let's Play | 129,700 | Let's Play |
| 64. | TetraNinja | Mass Effect 3 Walkthrough - Part 7 Explore the Citadel PS3 XBOX 360 PC (Gameplay / Commentary) | 128,921 | Walkthrough |
| 65. | TetraNinja | Mass Effect 3 Walkthrough - Part 8 New Normandy | 127,748 | Walkthrough |
| 66. | VGS - Video Game Sophistry | Mass Effect 3..Really, Jessica Chobot.........REALLY! | 123,605 | |
| 67. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 13 Feros Zhu's Hope Let's Play | 122,690 | Let's Play |
| 68. | TetraNinja | Mass Effect 3 Walkthrough - Part 11 Cerberus Lab | 117,563 | Walkthrough |
| 69. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 8 Citadel Homecoming Let's Play | 116,151 | Let's Play |
| 70. | TetraNinja | Mass Effect 3 Walkthrough - Part 9 Cortez and James PS3 XBOX 360 PC (Gameplay / Commentary) | 116,144 | Walkthrough |
| 71. | VGS - Video Game Sophistry | Mass Effect 3- Legion Recruits Some Primes | 115,126 | |
| 72. | Genol3oost | Mass Effect 3 | Thomas Bergersen - Hurt | 114,560 | |
| 73. | Genol3oost | Mass Effect 3 | Thomas Bergersen - Strength of a Thousand Men | 113,679 | |
| 74. | smudboy | ME3: The Top 20 Questionable Things Part 3 | 112,635 | |
| 75. | VGS - Video Game Sophistry | Mass Effect 3- Curing the Genophage with Wrex | 111,763 | |
| 76. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 11 Liara and Blue Force Fields Let's Play | 111,086 | Let's Play |
| 77. | VGS - Video Game Sophistry | Mass Effect 3- Admiral Hacket Finds My MAMMA! | 110,095 | |
| 78. | Егор Клёнов | Сюжет Mass Effect 3 без мишуры | 108,090 | |
| 79. | TetraNinja | Mass Effect 3 Walkthrough - Part 10 Brawl with James PS3 XBOX 360 PC (Gameplay / Commentary) | 106,707 | Walkthrough |
| 80. | smudboy | Mass Effect 3: Bookends of Destruction Part 1 | 105,808 | |
| 81. | Gaming Ambience | Mass Effect 3 - Citadel: Purgatory Bar (1 Hour of Music) | 105,582 | |
| 82. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 9 Crew Conversations #1 Let's Play | 103,057 | Let's Play |
| 83. | Lilija | Mass Effect 3 reactions - every time ME3 destroyed me emotionally | 101,044 | |
| 84. | TetraNinja | Mass Effect 3 Walkthrough - Part 12 Turian Palaven | 99,573 | Walkthrough |
| 85. | VGS - Video Game Sophistry | Mass Effect 3- Kelly Chambers After Citadel Attack | 99,439 | |
| 86. | VGS - Video Game Sophistry | Mass Effect 3- Joker Talks About His Sister... | 98,842 | |
| 87. | smudboy | Mass Effect 3: Bookends of Destruction Part 5 | 97,209 | |
| 88. | TetraNinja | Mass Effect 3 Walkthrough - Part 21 General Oraka PS3 XBOX 360 PC (Gameplay / Commentary) | 93,934 | Walkthrough |
| 89. | Sesto | Mass Effect 3 Ending: The Illusive Man kills Shepard | 90,609 | |
| 90. | VGS - Video Game Sophistry | Mass Effect 3 - Javik DOES Touch The Echo Shard | 89,815 | |
| 91. | TetraNinja | Mass Effect 3 Walkthrough - Omega DLC Part 1 Aria T'Loak Let's Play Gameplay Commentary | 89,168 | Walkthrough |
| 92. | TetraNinja | Mass Effect 3 Walkthrough - Part 20 Thane & Miranda PS3 XBOX 360 PC (Gameplay / Commentary) | 89,135 | Walkthrough |
| 93. | TheTrends Animated | Despicable Me 3 Hidden Secrets | 88,725 | |
| 94. | TetraNinja | Mass Effect 3 Walkthrough - Part 14 General Victus PS3 XBOX 360 PC (Gameplay / Commentary) | 87,764 | Walkthrough |
| 95. | VGS - Video Game Sophistry | Mass Effect 3: Citadel DLC: Sha'ira Easter Egg- Jab at Retakers? | 87,353 | |
| 96. | TetraNinja | Mass Effect 3 Walkthrough - Part 15 Normandy Malfunction PS3 XBOX 360 PC (Gameplay / Commentary) | 86,842 | Walkthrough |
| 97. | TetraNinja | Mass Effect Gameplay Walkthrough - Part 14 Lizbeth Let's Play | 84,761 | Let's Play |
| 98. | TetraNinja | Mass Effect 3 Walkthrough - Part 13 Communication Tower PS3 XBOX 360 PC (Gameplay / Commentary) | 84,382 | Walkthrough |
| 99. | Genol3oost | Mass Effect 3 | Thomas Bergersen - Homecoming | 82,966 | |
| 100. | TetraNinja | Mass Effect 3 Walkthrough - Part 22 Grissom Academy PS3 XBOX 360 PC (Gameplay / Commentary) | 82,532 | Walkthrough |
