| 1. |  GamePlayStation | MLB 2006 -- Gameplay (PS2) | 19,582 | |
| 2. |  KevinGohD | I never played this MLB game before | 14,675 | |
| 3. | someother1ne | MLB 2006 PSP PPSSPP gameplay HD 60fps (989 Sports, 2005) | 14,350 | |
| 4. | 2OT Sports Gaming | MLB 2006 (PS2) Giants vs Padres | 5,083 | |
| 5. | Timmii Gaming Channel | MLB 2006 - PS2 2005 (2006 World Series STL vs DET) | 4,423 | |
| 6. | Pichu London Sports | MLB 2006 | Sports Game Ballparks 🏟 ⚾️ | 2,031 | Let's Play |
| 7. | igcompany | MLB 2006 PSP Gameplay HD | 1,555 | |
| 8. | Timmii Gaming Channel | MLB 2006 - PS2 2005 (2006 AL East Rivals BOS vs NYY) | 1,003 | |
| 9. | 2OT Sports Gaming | MLB 2006 (PS2) Pirates vs Nationals | 989 | |
| 10. | Pichu London Sports | MLB 2006 - 2005 AAA All Star Game | 886 | |
| 11. | DSM The Editor | MLB 2006 (PS2) - All Stadium Intros | 728 | |
| 12. | Pichu London Sports | MLB 2006 - 2005 Southern League All Star Game | 720 | |
| 13. | Pichu London Sports | MLB 2006 - 2005 Texas League All Star Game | 505 | |
| 14. | 30-30 Club - Baseball Video Game Encyclopedia | MLB 2006 (PS2) - Intro 1 | 347 | |
| 15. | Pichu London Sports | MLB 2006 - 2005 Eastern League All Star Game | 328 | |
| 16. | 30-30 Club - Baseball Video Game Encyclopedia | MLB 2006 (PS2) - Intro 2 | 259 | |
| 17. | domino866 gameplay | MLB 2006 Dodgers vs Astros | 217 | |
| 18. | domino866 gameplay | MLB 2006 NL All Stars vs AL All Stars | 179 | |
| 19. | domino866 gameplay | MLB 2006 Giants vs Cubs | 162 | |
| 20. | domino866 gameplay | MLB 2006 Dodgers vs Brewers | 106 | |
| 21. | domino866 gameplay | MLB 2006 Astros vs Dodgers | 101 | |
| 22. | Magnate581 | Yankees vs Giants mlb 2006 ps2 clutch Ruben S. | 85 | |
| 23. | Magnate581 | Yankees vs Baltimore Orioles MLB 2006 ps2 | 81 | |
| 24. |  MicroChirp | MLB 2006 - Trailer | 76 | Preview |
| 25. | domino866 gameplay | MLB 2006 Tigers vs Brewers reposted | 60 | |
| 26. | domino866 gameplay | MLB 2006 New York Yankees vs Milwaukee Brewers | 46 | |
| 27. | domino866 gameplay | MLB 2006 Astros vs Braves | 35 | |
| 28. | domino866 gameplay | MLB 2006 Giants vs Astros | 31 | |
| 29. | HPC OTI | MLB 2006 Career Part 12 | 22 | |
