| 1. |  EazySpeezy | I tried speedrunning Motherload and was barely able to keep my sanity | 1,348 | |
| 2. | Blitz | Getting Rich By Mining Deep Treasure in Super Motherload | 486 | |
| 3. | Blitz | $1,000,000 Diamond Mining Jackpot in Super Motherload | 420 | |
| 4. | Nova Gnome Creations | I HIT THE YARNY MOTHERLOAD! 😍🧶 Yarn Haul & WIP Wednesday | 123 | |
| 5. | Tewtiy | THE MOST VALUABLE GEMS IN THE WORLD!! | Motherload | 85 | |
| 6. | LilArrin | Motherload Speedrun in 14:45 (Former WR) | 72 | |
| 7. | Tewtiy | SECRET FINAL BOSS!?! | Motherload | 69 | |
| 8. | xQc Gaming | xQc Plays MotherLoad | Classic Mining Game | 60 | Let's Play |
| 9. | Tewtiy | SO MANY ROCKS!! | Motherload | 59 | |
| 10. | Tewtiy | IS THIS THE FINAL BOSS?!? | Motherload | 56 | |
| 11. | RaceBandit | Let's Play Motherload (1) | 40 | Let's Play |
| 12. | syphic | Hit the Neo Geo & Turbografx Motherload!!! | 39 | |
| 13. | RaceBandit | Let's Play Motherload (2) | 24 | Let's Play |
| 14. | RaceBandit | Let's Play Motherload (12) - Finale | 21 | |
| 15. | IfOnlyWeHadACar | MotherLoad Heavy Industry extended | 20 | |
| 16. | LilArrin | Motherload Speedrun in 15:17 (Former World Record) | 18 | |
| 17. | RaceBandit | Let's Play Motherload (5) | 16 | |
| 18. | LilArrin | Motherload Speedrun in 15:08 (Former World Record) | 15 | |
| 19. | RaceBandit | Let's Play Motherload (4) | 13 | |
| 20. | RaceBandit | Let's Play Motherload (3) | 13 | |
| 21. | LilAggy VODs | DIGGING FOR AMAZONITE IN MOTHERLOAD - Flash Game Olympics [4] | 13 | |
| 22. | RaceBandit | Let's Play Motherload (10) | 10 | |
| 23. | OldSkuleNerd | REACTION to Mastodon The Motherload - Live for THROWBACK THURSDAY!!! | 9 | |
| 24. | LilArrin | Motherload Speedrun in 17:27 (Former World Record) | 9 | |
| 25. | Celca Gaming | Super Motherload - Let's Play ep 2 (Couple Coop) - We Almost Ran Out Of Fuel | 9 | |
| 26. | LilArrin | Motherload Speedrun in 15:29 (Former World Record) | 7 | |
| 27. | Grim Experience | PART 4: FAN MAIL MOTHERLOAD! Grim opens OVERWHELMING amount of FAN MAIL! June 17, 2014 | 6 | |
| 28. | RaceBandit | Let's Play Motherload (6) | 5 | |
| 29. | LilArrin | Motherload Speedrun in 16:23 (Former World Record) | 5 | |
| 30. | PHuffZone | The BEST WAY to run THE MOTHERLOAD!!! feat. PapaZone Carrying | 5 | |
| 31. | RaceBandit | Let's Play Motherload (9.5) | 5 | |
| 32. | GamingIsCake | ++18 The Motherload!! - Brewmaster Monk Tank PoV - TYRANNICAL BOLSTERING EXPLOSIVE AWAKENED PREPATCH | 4 | |
| 33. | RaceBandit | Let's Play Motherload (9) | 4 | |
| 34. | Grim Experience | RARE FIDGET SPINNER MOTHERLOAD! BIRTHDAY GIRL SHOPPING AND TOY UNBOXING! | 4 | Vlog |
| 35. | LilArrin | Motherload Speedrun in 15:53 (Former World Record) | 4 | |
| 36. | LilArrin | Motherload Speedrun (18:09) | 4 | |
| 37. | Celca Gaming | Super Motherload - Let's Play ep 6 (Couple Coop) - We're So Close Now! | 3 | |
| 38. | Beeeyeee | Diep.io: The Motherload! -Episode 3 | 3 | |
| 39. | KBGamer96 | Minecraft Troll Valley#3 ORE MOTHERLOAD!!!! | 3 | |
| 40. | TampaBay YoungGods | MotherLoad Expert | 3 | |
| 41. | Grim Experience | PART 1: Fan Mail MOTHERLOAD!! Grim opens overwhelming amount of YOUR Fan Mail!! | 3 | |
| 42. | EazySpeezy Plus | I try to speedrun motherload speedrun | 2 | |
| 43. | DoubleBacon ChaseBurger | My Christmas Haul 2021 (Sonic Figure Motherload)! | 2 | |
| 44. | Runescapefar Production | The Retro Game Files: Motherload Golidium Edition | 2 | |
| 45. | Icey Wolf | Finding the motherload!!!! Ep3 Ark Eternal and Parados | 2 | |
| 46. | Captain Fructose | Treasure! | Part 1 | Motherload | 2 | |
| 47. | popesquidward | THE POKÉMON CARD MOTHERLOAD.....😳 | 2 | |
| 48. | Grim Experience | PART 2: Fan Mail MOTHERLOAD! Grim opens OVERWHELMING amount of YOUR Fan Mail!! June 14, 2014 | 2 | |
| 49. | Play-Games-Com | Motherload - Full Gameplay Walkthrough | 1 | Walkthrough |
| 50. | Fellybishh | Motherload GO! | fellybishh on #Twitch | 1 | |
| 51. | Grim Experience | PART 3: Fan Mail MOTHERLOAD! Grim opens OVERWHELMING amount of your Mail! June 15, 2014 | 1 | |
