| 1. |  Ackatf | 765,075 | Let's Play MySims Agents - #27 Into The Nightmare Realm | 28:19 |
| 2. | NervousBunny | 76,428 | My Sims Agents Final | 18:58 |
| 3. | Sighawke | 68,477 | MySims Agents | Extra Ending Scene (Complete All Dispatch Missions) | 2:08 |
| 4. | Creative_Commander | 28,770 | MySims Agents DS Walkthrough: Episode 15: Series Finale: HQ Missions and Lovely Letters | 35:42 |
| 5. | IGN | 12,352 | MySims Agents Nintendo Wii Trailer - TGS 09: Trailer | 1:00 |
| 6. | Logstud97 | 10,330 | My Sims Agents Finale | 16:45 |
| 7. | LadyMpire | 8,278 | MySims Agents | 0:31 |
| 8. | KwingsLetsPlays | 7,692 | My Sims Agents Part 11 (Wii) Ultimate Selects | 2:33:34 |
| 9. | Jareas | 7,279 | The Story of MySims Agents 2 Leaked | 4:47 |
| 10. | CattusAhoy | 7,214 | MySims Agents Speedrun 2:10:28 | 2:14:06 |
| 11. | KitaNashStreams | 5,410 | MySims Agents [2019 STREAM] THE BEST SECRET AGENT - DS Gameplay/Walkthrough - Let's Play w/Kat | 3:32:56 |
| 12. | AeroDragon2 | 5,365 | Let's Play Mysims Agents Episode 13: Jungle Bungle | 20:07 |
| 13. | ProZD Plays Games | 3,830 | ProZD Plays MySims Agents // Ep 01: The Return of "Look At Everything" Lee | 30:09 |
| 14. | WizardToby | 3,177 | MySims Agents | #21 Nightmare Crown! [FINALE] | 30:55 |
| 15. | Family Friendly Gaming | 2,149 | My Sims Agents DS Episode 9 | 23:45 |
| 16. | Jason Hatt | 1,855 | MySims Agents Episode 69 Finale | 34:12 |
| 17. | Ziolot The Dragon Ch. | 1,733 | MySims Agents Speedrun World Record AFTER 2 YEARS!!! 1:12:52 | 1:15:27 |
| 18. | Zelda1Fan | 1,697 | MySims Agents Any% 1:45:24 | 1:53:47 |
| 19. | Games with Steve | 1,490 | MySims Agents - Gameplay & Interview | 1:36 |
| 20. | jbinminot | 1,257 | JB's 50 Favorite Nintendo DS Games Part 2 | 6:45 |
| 21. | Fishgirlviolet | 1,220 | Let's Play MySims Agents Part 47 | 15:00 |
| 22. | Jimby Stream Archive | 1,138 | MySims Agents #4 - Jimby Archive | 5:26:57 |
| 23. | Storster | 995 | Is MySims Agents a Hidden Gem? | 0:00 |
| 24. | AlbedoRecayson | 771 | Yuki Wants Her Lawyer #Shorts | 1:05 |
| 25. | dannyrom288 | 705 | Any interest in a "MySims Agents" TAS? | 2:14 |
| 26. | PokeGummy | 484 | Bring back Mysims Agents!! | 0:00 |
| 27. | Blank Slayte (Bigmariofan99) | 453 | MySims Agents Comic Pages | 2:08 |
| 28. | LumiePlays | 361 | The End - MYSIMS AGENTS PART 8 - LumiePlays | 17:44 |
| 29. | Ashley Norton Gaming | 318 | Life Updates and Cool Spy Glasses - MySims Agents Part 6 | 2:06:50 |
| 30. | Bad Game Buddies | 295 | MySims Agents [3] - A New Base and New Case! | 0:00 |
| 31. | Yhe_OldWyvernOne Gaming | 191 | My Sims Agents 1 00 | 0:49 |
| 32. | PixelaGames2000 | 184 | live stream lets play my sims agents part 7 finale! | 1:54:25 |
| 33. | ChaiPanDuh | 152 | Mad Scientist Time! (MySims Agents pt 4) | 37:39 |
| 34. | The Calamity Carl | 151 | I Got Bored- My Sims Agents | 31:53 |
| 35. | dreamerofchaos1 | 137 | MySims Agents-Part 3 Finale | 7:04 |
| 36. | Adventurousduelist | 137 | MySims Agents But It's 2021 | 9:47 |
| 37. | Yhe_WyvernTrue PlayWorksTv | 127 | MySims Agents | 1:05 |
| 38. | GameFly | 126 | MySims Agents The Case Trailer | 1:11 |
| 39. | Beta64 Live - Twitch Archive | 117 | [Beta64 Live] Pikuniku, Lil Gator Game, MySims Agents, Chibi-Robo: Clean Sweep, and more! | 2:10:11 |
| 40. | Kei Sensuki | 89 | 【MYSIMS AGENTS】Becoming a SECRET AGENT! | 0:00 |
| 41. | Casandra O'Connor | 89 | my sims agents episode 10 part 2 | 16:00 |
| 42. | Berry Violet Couture | 77 | MySims Agent - Hanging out and playing with Tobor | 6:59 |
| 43. | Hat's How You Do It | 72 | MySims Agents #2 - Hat's How You Do It | 19:24 |
| 44. | Twitch Clips - Beta64 | 63 | Beta64 Live - H U M A N B O N E S | 0:10 |
| 45. | Aura The Doof | 49 | MySims Agents Stream #1 (Stream VOD 4/6/2020) | 2:20:11 |
| 46. | Alvinic | 39 | My Sims Agents | 13:14 |
| 47. | Sandra_chi Ch. | 38 | THIS IS SOMEHOW WORSE THAN THE FIRST ENDING?? | MySims Agents [Full FINALE - 4] | 57:59 |
| 48. | Songof Luxray | 29 | Secret Agent Sim! Secret Agent Sim! (MySims: Agents Part 5) | 1:19:04 |
| 49. | Pleasantly Plump | 24 | AVGK Episode 5: MySims Agents (Wii) | 2:58 |
| 50. | Rebecca Irwin | 19 | I play MySims Agents part 1 | 18:08 |
| 51. | PlutoGam3r | 19 | let's have a bit of nostalgia | My Sims Agents | 1:51:22 |
| 52. | Archangel LIVE | 18 | childhood game time | My Sims Agents for the Wii | 2:22:18 |
| 53. | CowKingMM | 18 | MySims Agents: Neighborhood Dog Napping | 14:48 |
| 54. | CluelessAnon Streams | 11 | Wii Variety Stream (8/29/24) - The Wii Wheel of Whimsy! | 0:00 |
| 55. | deathline | 9 | MySims Agents | Any% - 1:49:25 | 1:51:34 |
| 56. | Gemini Girl Gamer | 6 | MySims Agents {1} | 19:29 |
