| 1. | 39daph vods | 39daph Plays Puzzle Agent | 232,735 | Let's Play |
| 2. | Fuse4Gaming | September 2011 CONTEST! (Ended) | 1,591 | |
| 3. | Fuse4Gaming | September 2011 (Puzzle Agent) Contest WINNER! (UPDATE) | 681 | |
| 4. | Fuse4Gaming | September 2011 (Puzzle Agent) Contest WINNER! | 456 | |
| 5. | rinimt | Puzzle Agent - 29:12! | 349 | |
| 6. | rinimt | Puzzle Agent - 100% in 36:16 | 125 | |
| 7. | owlsighs | [1] Puzzle Agent [Owl Playthrough] | 105 | Let's Play |
| 8. | owlsighs | [5][FINAL] Puzzle Agent [Owl Playthrough] | 78 | Let's Play |
| 9. | owlsighs | [2] Puzzle Agent [Owl Playthrough] | 70 | Let's Play |
| 10. | Una Yamakuma 山熊ウナ Ch. | [Puzzle Agent] Here we go again, PUZZLES FEED ME!!! [Vtuber] | 66 | |
| 11. | Namoochi | 🔴EN VTUBER| Puzzle Agent pt.2 and Among Us with viewers! | 63 | |
| 12. | owlsighs | [4] Puzzle Agent [Owl Playthrough] | 61 | Let's Play |
| 13. | owlsighs | [3] Puzzle Agent [Owl Playthrough] | 57 | Let's Play |
| 14. | I Am Heroic | TALK TO CREEPY MAN | Puzzle Agent | Detective Time | 1 | 50 | |
| 15. | I Am Heroic | SOMETHING FISHY GOING ON | Puzzle Agent | Detective Time | 5 | 50 | |
| 16. | Namoochi | 🔴EN VTUBER| Puzzle Agent pt.1 | 46 | |
| 17. | PiranhaCupcake | Puzzle Agent [Ending] | 41 | |
| 18. | Grey Wuskerfluff Ch. | GNOMES! | 39 | |
| 19. | PiranhaCupcake | Puzzle Agent [01] | 38 | |
| 20. | cowboyotis | Let's Stream: Puzzle Agent | 33 | |
| 21. | ShifterChaos | Lets Play Puzzle Agent: Just Another Day On The Job (1/9) | 31 | |
| 22. | GXP Gaming | Meet Nelson Tethers || Puzzle Agent Part 1 | 28 | |
| 23. | I Am Heroic | INCONSISTENT ABNORMALITIES | Puzzle Agent | Detective Time | 3 | 22 | |
| 24. | GXP Gaming | Gnomes Scare Me Now || Puzzle Agent FINALE | 19 | |
| 25. | ShifterChaos | Lets Play Puzzle Agent: Quando Omni Flunkus, Mortati (6/9) | 16 | |
| 26. | I Am Heroic | HE.....IS STEVE | Puzzle Agent | Detective Time | 2 | 16 | |
| 27. | I Am Heroic | FURIOUS OVER FISH | Puzzle Agent | Detective Time | 6 | 15 | |
| 28. | Frog Productions | Puzzling the Agent | 14 | |
| 29. | FinalCut | Puzzle Agent • Part 1 | 14 | |
| 30. | ShifterChaos | Lets Play Puzzle Agent: A Warm Scoggins Welcome (2/9) | 13 | |
| 31. | GXP Gaming | Restaurant Riddles! || Puzzle Agent Part 4 | 12 | |
| 32. | GXP Gaming | Thieving Gnomes!! || Puzzle Agent Part 6 | 10 | |
| 33. | CatGirl George | Puzzle Agent - On Air! | 10 | |
| 34. | GXP Gaming | The Moose Ear Diner || Puzzle Agent Part 3 | 9 | |
| 35. | RoflLobster | Day 561: Puzzle Agent | 9 | |
| 36. | That Imp Girl | Puzzle Agent Episode 1 | 8 | |
| 37. | Jon Renish | Steam Cleaning - Puzzle Agent | 8 | |
| 38. | Grey Wuskerfluff Ch. | Puzzle Agent: The investigation comes to its Conclusion? 7/7 | 8 | |
| 39. | That Imp Girl | Puzzle Agent Ending! | 8 | |
| 40. | RoflLobster | Day 563: It was a tragic accident | 8 | |
| 41. | I Am Heroic | I'VE BEEN GNOMED! | Puzzle Agent | Detective Time | 4 | 8 | |
| 42. | ShifterChaos | Lets Play Puzzle Agent: The Gnomes Made Me Do It (9/9) | 8 | |
| 43. | RoflLobster | Tethers and I both checked out | 7 | |
| 44. | FinalCut | Puzzle Agent • Part 3 | 7 | |
| 45. | ShifterChaos | Lets Play Puzzle Agent: Pie and Coffee (3/9) | 7 | |
| 46. | FinalCut | Puzzle Agent • Part 5 • ENDING | 7 | |
| 47. | PiranhaCupcake | Puzzle Agent [05] | 7 | |
| 48. | ShifterChaos | Lets Play Puzzle Agent: Back to the Future On Ice! (4/9) | 7 | |
| 49. | ShifterChaos | Lets Play Puzzle Agent: Hostile Hostesses and Shady Sheriffs (8/9) | 7 | |
| 50. | FinalCut | Puzzle Agent • Part 4 | 7 | |
| 51. | ShifterChaos | Lets Play Puzzle Agent: A Puzzle Game With Jump Scares (5/9) | 7 | |
| 52. | PiranhaCupcake | Puzzle Agent [02] | 6 | |
| 53. | PiranhaCupcake | Puzzle Agent [11] | 6 | |
| 54. | Grey Wuskerfluff Ch. | Puzzle Agent 2: Talking to the Sheriff. 2/6 | 6 | |
| 55. | FinalCut | Puzzle Agent • Part 2 | 6 | |
| 56. | GXP Gaming | Icy Lobster || Puzzle Agent Part 5 | 6 | |
| 57. | GXP Gaming | Word Problems || Puzzle Agent Part 2 | 6 | |
| 58. | PiranhaCupcake | Puzzle Agent [03] | 6 | |
| 59. | Grey Wuskerfluff Ch. | Puzzle Agent: The investigation Begins 1/7 | 5 | |
| 60. | I Am Heroic | THE FINAL PIECE | Puzzle Agent | Detective Time | Finale | 5 | |
| 61. | GXP Gaming | The Secret Society || Puzzle Agent Part 7 | 5 | |
| 62. | GXP Gaming | Gnomes Strike Again! || Puzzle Agent Part 8 | 5 | |
| 63. | ShifterChaos | Lets Play Puzzle Agent: Some Real Stumpers (7/9) | 4 | |
| 64. | PiranhaCupcake | Puzzle Agent [12] | 4 | |
| 65. | PiranhaCupcake | Puzzle Agent [09] | 4 | |
| 66. | PiranhaCupcake | Puzzle Agent [07] | 4 | |
| 67. | PiranhaCupcake | Puzzle Agent [04] | 4 | |
| 68. | GXP Gaming | The Factory || Puzzle Agent Part 9 | 4 | |
| 69. | PiranhaCupcake | Puzzle Agent [08] | 4 | |
| 70. | PiranhaCupcake | Puzzle Agent [06] | 4 | |
| 71. | PiranhaCupcake | Puzzle Agent [13] | 3 | |
| 72. | Grey Wuskerfluff Ch. | Puzzle Agent: The investigation Begins 2/7 | 3 | |
| 73. | Grey Wuskerfluff Ch. | Puzzle Agent 2: Getting that Hot Dish. 5/6 | 3 | |
| 74. | PiranhaCupcake | Puzzle Agent [10] | 3 | |
| 75. | Grey Wuskerfluff Ch. | Puzzle Agent: The investigation Nears its end! 6/7 | 2 | |
| 76. | Natal Plays Games | Natal Plays Nelson Tethers Puzzle Agent 1 | 2 | Let's Play |
| 77. | Grey Wuskerfluff Ch. | Puzzle Agent: The investigation Begins 3/7 | 2 | |
| 78. | 420 GAMING | 420 GAMING - Nelson Tethers: Puzzle Agent - With the wife | 1 | |
| 79. | Grey Wuskerfluff Ch. | Puzzle Agent: The investigation Begins 4/7 | 1 | |
| 80. | Game-A-Dayer | Day 374 - Puzzle Agent | 1 | |
| 81. | Grey Wuskerfluff Ch. | Puzzle Agent: The investigation Begins 5/7 | 1 | |