| 2024-09-08 |  GuinhOOver | 2,420 | Serious Sam SE | #VR #Quest2 #Quest3 #FPS #PSVR2 #SeriousSam | 0:00 |
| 2024-07-20 | Gameplay Streak | 36,600 | SERIOUS SAM 2 - Level 42 Mental Institution Gameplay Walkthrough [4K60FPS] - No Commentary | 42:04 |
| 2024-07-17 | Highest Gameplay | 186 | Serious Sam 2 Gameplay [4K 60FPS] - FULL GAME | 7:41:32 |
| 2024-05-06 | Wandreson SN | 1,970 | Serious Sam 2 Winlator 6.1 SD 8gen3 #redmik70pro #viral #shorts #winlator | 0:49 |
| 2024-05-03 | Thiago-Skull Games | 638 | Serious Sam: muito tiro e correria nesse jogo | 34:46 |
| 2024-05-01 | Retro Setup Lab | 865 | EP202 - AMD OPTERON OPRESSOR RODANDO GAMES NO WINDOWS XP 64 BITS: + ATI RADEON E AUDIGY 2 ZS | 4:02:39 |
| 2024-01-06 | BOMBEIRAO | 274 | Serious Sam Collection - PC Gameplay RADEON 800 MHZ 1.84 TFLOPS | 10:30 |
| 2023-09-15 | SirVeneno | 3,190 | MILHÕES DE INIMIGOS AO MESMO TEMPO!!! Serious Sam 2 | 1:41:10 |
| 2023-09-01 | Espaço de Jogos | 1,310 | To play Serious Sam 2 #shorts #serioussam2 #comedy #memes #gameplay | 0:16 |
| 2023-08-09 | VLAD DIEZEL GAMES JR | 58 | SERIOUS SAM ©2 | 50:20 |
| 2022-09-10 | DanilegoPlays | 5,160 | Serious Sam 3 #2 - Na Teia da Aranha (pt-br)(Serious Mode)[REUPLOAD] | 34:21 |
| 2022-06-23 | MWS | 237 | Serious Sam II Multiplayer (2022) | 14:00 |
| 2022-04-12 | CineVibes | 407 | Serious Sam 2 - Lembra desse Jogo? Live ON | 1:18:00 |
| 2022-04-11 | Do Começo | 14,600 | Serious Sam live do jogo | 38:49 |
| 2022-04-01 | GabrielOnuris | 10,400 | Serious Sam 2: A ovelha negra da franquia | 13:25 |
| 2022-03-16 | RTecnológico | 1,240 | LIVE DE SERIOUS SAM 2 PT 7!! FINAL. | 2:56:39 |
| 2022-03-13 | Kindred | 346 | serious sam 2 froze my pc | 0:09 |
| 2021-07-17 | Slenderman Games | 3,370 | QUATRO IDIOTAS NUM JOGO ESQUIZOFRENICO/Serious Sam 2 (Ft.Fellipy CZ, MulaBR E JL) | 9:36 |
| 2021-06-01 | Now Loading Please Wait | 2,470 | Serious Sam II - Xbox | 0:40 |
| 2021-04-23 | Um_BR | 364 | Serious Sam 2. Jogatina de Teste II | 1:19:12 |
| 2021-02-14 | Literalmente{Game} | 2,890 | Showcase - Otimizações na renderização no Play! (PS2) | 8:09 |
| 2020-08-12 | AlanGHP7 | 1,770 | SERIOUS SAM 2 INFINITO-FINAL LONGO-#16 | 36:30 |
| 2020-05-21 | AlanMix | 117 | game design de 2001 | 1:14 |
| 2020-03-14 | Canal Virtual | 56,100 | SERÁ QUE SERIOUS SAM 2 RODA EM PC FRACO? | 22:20 |
| 2020-01-02 | KURUMIN GAMES | 1,300 | Serius Sam 2 | 32:28 |
| 2019-07-05 | BESTINHA GAMER | 11,900 | UNTURNED NOVO MAPA VERSÃO 3.9.9.5 EXPLORANDO O MAPA LIVE AOVIVO 2019 PC LIXO SEM PLACA DE VIDEO | 1:33:25 |
| 2018-09-19 | Game Vs Games | 200 | SERIOUS SAM 2 XBOX CLASSÍCO | 34:36 |
| 2016-07-13 | OH SANTANA | 21,400 | [SS] #1 - Serious Sam 2 | 8:34 |
| 2016-03-20 | KingDesu | 987 | Serious Sam 2 ''Adeus Strike! - Momento morrendo Bagarai SUPREMO!'' | 26:34 |
| 2016-01-30 | COOLER-BR | 33,300 | AO VIVO JOGANDO -SERIOUS SAM 2-e csgoo | 1:50:25 |
| 2014-10-18 | Kyra44 A F M | 131 | Serious Sam 2 - Easter Egg Duke Nukem | 0:30 |
| 2013-04-05 | Luis | 74,900 | Defiance Detonado/Playthrough Coop com Serious Sam #2 [PT-BR] | 21:40 |
| 2012-07-18 | Pedrão84 | 39,500 | Serious Sam: The First Encounter - Ugh Zan III - Final Boss [HD] | 27:28 |
| 2012-05-22 | henrique9415 | 36,200 | Gameplay Serious Sam 2 | 11:35 |
