| 1. | Bear is Driving | SpaceChem - Random Oxides - 16 Symbols | 5,682 | |
| 2. | hero5th | Lets Play SpaceChem Pt 1- Introductions are boring | 3,883 | Let's Play |
| 3. | Dtexas | SpaceChem - Theres Something in the Fishcake - Planet 2, Level 5 (Inside the Reactor) | 3,727 | |
| 4. | Dtexas | SpaceChem - Theres Something in the Fishcake - Planet 2, Level 5 (Outside the Reactor) | 1,851 | |
| 5. | Bear is Driving | SpaceChem - Moustachium 608 (907/1/51) | 1,591 | |
| 6. | hero5th | Lets Play SpaceChem Pt 2 - your the rubber, I'm the glue and Scissors | 1,107 | Let's Play |
| 7. | Bear is Driving | SpaceChem - Danger Zone - 12 Symbols | 1,068 | |
| 8. | adlingtont | CYOV - SpaceChem VS AAA: For The Awesome - Choose Your Own Video | 947 | |
| 9. | Bear is Driving | SpaceChem - Under the Ice - 15 Symbols | 809 | |
| 10. | adlingtont | CYOV - SpaceChem VS Fate of The World - Choose Your Own Video | 776 | |
| 11. | hero5th | Lets Play SpaceChem Pt - 3 - Almost a whole new world. | 743 | Let's Play |
| 12. | hero5th | Lets Play SpaceChem Pt- 4 : The errors start to show. | 698 | Show |
| 13. | adlingtont | CYOV 14 - SpaceChem - Choose Your Own Video | 632 | |
| 14. | hero5th | A breif introduction to SpaceChem. | 614 | |
| 15. | hero5th | Lets Play SpaceChem Pt-5: It takes Split Before Bonding ³ | 538 | Let's Play |
| 16. | FourCourtJester | Humble Indie Bundle - SpaceChem | 492 | |
| 17. | Dtexas | SpaceChem - An Introduction to Pipelines - Planet 2, Level 4 | 491 | |
| 18. | hero5th | Lets Play SpaceChem Pt-7: Nothing works! | 460 | Let's Play |
| 19. | Bear is Driving | SpaceChem - Every Day is the First Day - 12 Symbols | 449 | |
| 20. | hero5th | Lets Play SpaceChem Pt-8: It works! | 402 | Let's Play |
| 21. | hero5th | Lets play SpaceChem Pt-6: Settling into the routine | 400 | Let's Play |
| 22. | hero5th | Lets Play SpaceChem Pt-9: Challenge: In-Place Swap, NH3 | 336 | Let's Play |
| 23. | hero5th | Lets play SpaceChem Pt 11: My mic is a most unfortunate Malfunction. | 336 | Let's Play |
| 24. | hero5th | Lets Play SpaceChem Pt36-5: Ending of Pt36 | 333 | Let's Play |
| 25. | Dtexas | SpaceChem - Double Bonds - Planet 2, Level 1 | 330 | |
| 26. | hero5th | Lets Play SpaceChem Pt 12: A sense prelude to random Oxides | 282 | Let's Play |
| 27. | hero5th | Lets watch, SpaceChem Pt9-5: 'The out takes' | 282 | |
| 28. | hero5th | Lets Play SpaceChem Pt 18: Going Green | 256 | Let's Play |
| 29. | hero5th | Lets Play SpaceChem Pt-10: The Mic had died, at the shocking conclusion! | 253 | Let's Play |
| 30. | hero5th | Lets Play SpaceChem Pt 36: Special Guest Alex. | 235 | Let's Play |
| 31. | hero5th | Lets Play SpaceChem Pt 13: What a headache. | 216 | Let's Play |
| 32. | Dtexas | SpaceChem - Multiple Outputs - Planet 2, Level 3 | 194 | |
| 33. | hero5th | Lets Play SpaceChem Pt 15: No really, no thanks necessary. | 189 | Let's Play |
| 34. | hero5th | Lets Play SpaceChem Pt 14: What a migraine | 186 | Let's Play |
| 35. | hero5th | Lets Play Spacechem Pt 16: Well, go call the plummer. | 174 | Let's Play |
| 36. | hero5th | Lets play SpaceChem PT 17-5: Tinkers are me, and gnomes. | 170 | Let's Play |
| 37. | hero5th | Lets Play SpaceChem Pt 19: A solution that wasn't mine | 160 | Let's Play |
| 38. | hero5th | Lets Play SpaceChem Pt 17: NP, no really, no progress. | 152 | Let's Play |
| 39. | Dtexas | SpaceChem - Moustachium 602 Challenge | 151 | |
| 40. | hero5th | Lets Play SpaceChem Pt 22: Its only Applied Fusion. | 150 | Let's Play |
| 41. | hero5th | Lets play SpaceChem Pt 19-Pre: The failed attempts. | 139 | Let's Play |
| 42. | hero5th | Lets play SpaceChem Pt 35: Thoughts of problems | 133 | Let's Play |
| 43. | hero5th | Lets Play SpaceChem Pt 25: If only we had sulfuric acid to tricalcium phosphate | 132 | Let's Play |
| 44. | Carl Siemens | SpaceChem - Every Day is the First Day (263/1/34) | 111 | |
| 45. | hero5th | Lets Play SpaceChem Pt 21: Superman would be happy. | 101 | Let's Play |
| 46. | hero5th | Lets Play SpaceChem 26: Exploding Head syndrom | 98 | Let's Play |
| 47. | hero5th | Lets play SpaceChem Pt 34: Progress in the right direction. | 93 | Let's Play |
| 48. | hero5th | Lets Play SpaceChem Pt 31: Gas Work Park | 92 | Let's Play |
| 49. | hero5th | Lets Play SpaceChem Pt 27: Boom. | 92 | Let's Play |
| 50. | hero5th | Lets Play SpaceChem Pt 20: Something is Chilly here | 89 | Let's Play |
| 51. | hero5th | Lets Play SpaceChem Pt 23: Divide and CONQUER! | 86 | Let's Play |
| 52. | Bear is Driving | SpaceChem: In-Place Swap One Reactor | 84 | |
| 53. | hero5th | Lets Play SpaceChem Pt 30: The non existing compound | 82 | Let's Play |
| 54. | hero5th | Lets play SpaceChem Pt 33: Progress | 81 | Let's Play |
| 55. | hero5th | Lets Play SpaceChem Pt 28: 'Sacre bleu' said the boss | 79 | Let's Play |
| 56. | hero5th | Lets Play SpaceChem Pt 24: Safety glasses beyond this point | 78 | Let's Play |
| 57. | Dtexas | SpaceChem - Best Left Unanswered - Planet 2, Level 2 | 74 | |
| 58. | hero5th | Lets Play SpaceChem Pt 29: Danger Plot Foundry | 72 | Let's Play |
| 59. | hero5th | Lets Play SpaceChem Pt 32: References. | 70 | Let's Play |
| 60. | hero5th | Let us play SpaceChem Ice to meet you | 49 | |
| 61. | deryell | Let's Check Out: Spacechem | 37 | |
| 62. | hero5th | Let us play SpaceChem, Swap place in | 31 | |
| 63. | D33ZL3 | SpaceChem - Sleepless on Sernimir IV (950/2/40) | 23 | |
| 64. | hero5th | Lets Play SpaceChem Pt 18-5: going green conclusion. | 20 | Let's Play |
| 65. | hero5th | Lets Play SpaceChem : Random Oxides Lets us play | 18 | Let's Play |
| 66. | Nirakolov | How Not to SpaceChem - Part 1: QT-2 | 16 | |
| 67. | The Detective on Twitch | Steam Backlog Series: SpaceChem | 16 | |
| 68. | hero5th | Lets play SpaceChem Pt 17-75: You can thank me now. | 14 | Let's Play |
| 69. | Michael | SpaceChem Walkthrough - Multiple Outputs | 6 | |
| 70. | D33ZL3 | SpaceChem - Slightly Different (60/1/20) | 6 | |
| 71. | D33ZL3 | SpaceChem - There's Something in the Fishcake (494/1/16) | 6 | |
| 72. | D33ZL3 | SpaceChem - Of Pancakes and Spaceships (55/1/22) | 6 | |
| 73. | D33ZL3 | SpaceChem - Split Before Bonding (256/1/27) | 5 | |
| 74. | D33ZL3 | SpaceChem - Best Left Unanswered (138/1/18) | 4 | |
| 75. | D33ZL3 | SpaceChem - An Introduction to Bonding (119/1/17) | 4 | |
| 76. | D33ZL3 | SpaceChem - Every Day is the First Day (295/1/40) | 4 | |
| 77. | D33ZL3 | SpaceChem - A Brief History of SpaceChem (139/1/18) | 4 | |
| 78. | RoflLobster | Day 654: Falling asleep with spacechem before the weekend | 2 | |
| 79. | D33ZL3 | SpaceChem - Double Bonds (117/1/17) | 2 | |
| 80. | D33ZL3 | SpaceChem - Removing Bonds (58/1/16) | 1 | |
| 81. | D33ZL3 | SpaceChem - Multiple Outputs (147/1/18) | 1 | |
| 82. | D33ZL3 | SpaceChem - Crossover (157/1/16) | 1 | |
| 83. | D33ZL3 | SpaceChem - It Takes Three (315/1/37) | 0 | |