| 1. |  LetsPlay | Play Pals - The Doctors Are Back - Surgeon Simulator 2 | 399,460 | Let's Play |
| 2. | HaroldArtistPlay | SOMOS LOS MEJORES DOCTORES DE SURGEON SIMULATOR 2 ft ElPipi | 258,245 | Let's Play |
| 3. | LetsPlay | You're In Our Care Now - Surgeon Simulator 2 Multiplayer | 185,014 | Let's Play |
| 4. | Sajk and Friends | Sykkuno plays Surgeon Simulator 2 with Valkyrae and Fuslie | 23,822 | Let's Play |
| 5. | IGN | Surgeon Simulator 2 Let's Play With (Blurred) IRL Open-Heart Surgery Footage | gamescom 2020 | 16,608 | Let's Play |
| 6. | DansGaming | Let's Play Surgeon Simulator 2 - Early Access Part 1 | 2,283 | Let's Play |
| 7. | Rage Proof Gaming | Why did he do that to his head #shorts #surgeonsimulator2 #gaming #gameplay #doctor #simulator #rpg | 1,512 | Let's Play |
| 8. | BlackGaymerGod | BlackGaymerGod Plays Surgeon Simulator 2 | 1,070 | Let's Play |
| 9. | ethanb0206 | Clone Plays Apps - Surgeon Simulator | 649 | Let's Play |
| 10. | DansGaming | Let's Play Surgeon Simulator 2 - Early Access Part 2 | 615 | Let's Play |
| 11. | GavynXP | Surgeon Simulator 2 with my Dad! | Grey's Anatomy Dr. Webber | 570 | Let's Play |
| 12. | DansGaming | Let's Play Surgeon Simulator 2 - Early Access Part 3 | 361 | Let's Play |
| 13. | Rage Proof Gaming | This is a doctors morning routine #shorts #surgeonsimulator2 #gameplay #doctor #simulator #rpg | 320 | Let's Play |
| 14. | DansGaming | Let's Play Surgeon Simulator 2 - Early Access Part 4 | 265 | Let's Play |
| 15. | Ezekiel III | Zeke Plays: Surgeon Simulator 2 (Closed Beta) | 222 | Let's Play |
| 16. | DansGaming | Let's Play Surgeon Simulator 2 - Early Access Part 6 | 218 | Let's Play |
| 17. | November Bravo | I am Bad at Games - Surgeon Simulator 2 | 215 | Let's Play |
| 18. | DansGaming | Let's Play Surgeon Simulator 2 - Early Access Part 5 | 210 | Let's Play |
| 19. | DansGaming | Let's Play Surgeon Simulator 2 - Early Access Part 7 | 204 | Let's Play |
| 20. | Rage Proof Gaming | We lost our medical license because of this - Surgeon Simulator 2 | 93 | Let's Play |
| 21. | Black Hole Gaming | মুখোশধারী ভদ্রমহিলা সাহায্য প্রয়োজন Masked Lady Needs Help Black Hole Gaming #Surgery simulator 2 | 76 | Let's Play |
| 22. | Timrongames | I hope my malpractice insurance is paid up in Surgeon simulator 2 - First Time Playing | 44 | Let's Play |
| 23. | November Bravo | WE are Bad at Games - Surgeon Simulator 2 | 43 | Let's Play |
| 24. | Mariojacob7red | Surgeon Simulator 2 - Alpha Version | 28 | Let's Play |
| 25. | Mostly Bad Ideas | Let's Play Some Surgeon Simulator 2: Ep.1 | 24 | Let's Play |
| 26. | 「space」 | Surgeon Simulator 2 : Let's Play I EP 1 | I Made A Monster!! | 20 | Let's Play |
| 27. | Menace II Gaming | Surgeon Simulator : DR.SMITH HEART SURGERY CLINIC "RESULTS MAY VARY...ALOT" Part 1 | Letsplay | 17 | Let's Play |
| 28. | SavePoint | Dr. Potato sued for malpractice??? | Surgeon Sim 2 - Potato Pals | 12 | Let's Play |
| 29. | briteboom | Surgeon Simulator 2 "Playthrough" | 9 | Let's Play |
| 30. | 「space」 | Surgeon Simulator 2 : Let's Play I EP 2 | Forgot About This Playthrough Lol | 7 | Let's Play |
| 31. | Alexander A. Manzoni | The Poet Plays: Surgeon Simulator 2-- FAIL! FIRST TIME CRINGE -- (Twitch Livestream: 1/29/23) | 3 | Let's Play |
