| 1. |  Team Alpha | Alphabirth: The End Times [Release Trailer] | 378 | Let's Play |
| 2. | Neco The Sergal | 2 New Endings! Certificate of Termination & Survival | No Delivery - [Part 9] | 252 | Let's Play |
| 3. | michaelalfox | Foxman Plays: The Binding of Isaac - Ep. 4 - Rebirth of a Fox | 205 | Let's Play |
| 4. | Neco The Sergal | New Ending - Certificate of Death | No Delivery - [Part 10] | 195 | Let's Play |
| 5. | michaelalfox | Foxman Plays: The Binding of Isaac - Episode 4 - Danzig | 165 | Let's Play |
| 6. | Meruru | 【The Binding of Isaac】guerilla! ♡ help me wake up for my errands c: | 112 | Let's Play |
| 7. | michaelalfox | Foxman Plays: The Binding of Isaac - Ep. 6 - Parasite | 102 | Let's Play |
| 8. | Phedran | INFINIDEATH : The Binding of Isaac - 01 - Welp | 101 | Let's Play |
| 9. | VanguardOfValor | VoV Plays The Binding Of Isaac - Isaac - Part 1: Tears Of Joy | 98 | Let's Play |
| 10. | Graeme Games | Let's Play Riddle Transfer 2 (Old) | 10th Anniversary | 90 | Let's Play |
| 11. | VanguardOfValor | VoV Plays The Binding Of Isaac - Isaac - Part 3: Your Own Worst Enemy | 85 | Let's Play |
| 12. | michaelalfox | Foxman Plays: The Binding of Isaac - Ep. 5 - Contact | 73 | Let's Play |
| 13. | VanguardOfValor | VoV Plays The Binding Of Isaac - Isaac - Part 2: Doctor's Orders | 70 | Let's Play |
| 14. | Phedran | INFINIDEATH : The Binding of Isaac - 02 - Dmg Up | 53 | Let's Play |
| 15. | FullGrownGaming | Let's Play The Binding of Isaac Episode 1 :: Road to Platinum | 50 | Let's Play |
| 16. | Graeme Games | ACTION RPG ROGUELIKE | Let's Play REYNARD | Graeme Games | First Look Gameplay | 40 | Let's Play |
| 17. | Graeme Games | Let's Play Riddle Transfer (Old) | 10th Anniversary | 37 | Let's Play |
| 18. | Phedran | INFINIDEATH : The Binding of Isaac - 03 - Chubby | 36 | Let's Play |
| 19. | Newfie Bangaa | Let's Play The Binding of Isaac #60 - Shopping List [Final] | 33 | Let's Play |
| 20. | Phedran | INFINIDEATH : The Binding of Isaac - 04 - Shot | 29 | Let's Play |
| 21. | Phedran | INFINIDEATH : The Binding of Isaac - 05 - Carry | 28 | Let's Play |
| 22. | Phedran | INFINIDEATH : The Binding of Isaac - 06 - Trail | 27 | Let's Play |
| 23. | Phedran | INFINIDEATH : The Binding of Isaac - 07 - Curse | 24 | Let's Play |
| 24. | Newfie Bangaa | Let's Play The Binding of Isaac #53 - Alphabet Soup Redux | 22 | Let's Play |
| 25. | Phedran | INFINIDEATH : The Binding of Isaac - 09 - Knights | 22 | Let's Play |
| 26. | Newfie Bangaa | Let's Play The Binding of Isaac #42 - Alphabet Soup | 19 | Let's Play |
| 27. | Phedran | INFINIDEATH : The Binding of Isaac - 08 - Miscalculation | 15 | Let's Play |
| 28. | SlowWolf | The Binding of Isaac: AB - Let's Play! 01 [Clutch] | 12 | Let's Play |
| 29. | TonyD Gaming | Adventure Craft Pre Alpha Demo! Part 3 - WE LOST IT ALL! | 9 | Let's Play |
| 30. | Noise Berry Games | Jon's Watch - Bardbarian | 8 | Let's Play |
| 31. | SlowWolf | The Binding of Isaac: AB - Let's Play! 26 [Straightforward] | 8 | Let's Play |
| 32. | Dean Lofi Plays | Slime 3K - NEW Smiley Slime Horde Survival Roguelite!!! | 8 | Let's Play |
| 33. | SlowWolf | The Binding of Isaac: AB - Let's Play! 11 [Crystal] | 7 | Let's Play |
| 34. | Noise Berry Games | SerJonPlays: Binding Of Isaac: Episode 1: All The Hearts! | 7 | Let's Play |
| 35. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 07 [Bassackwards] | 6 | Let's Play |
| 36. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 28 [Wasteland King] | 6 | Let's Play |
| 37. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 11 [Pong] | 6 | Let's Play |
| 38. | SlowWolf | The Binding of Isaac: AB - Let's Play! 38 [Posthumous] | 6 | Let's Play |
| 39. | SlowWolf | The Binding of Isaac: AB - Let's Play! 24 [Returned] | 6 | Let's Play |
| 40. | SlowWolf | The Binding of Isaac: AB - Let's Play! 28 [Peak] | 6 | Let's Play |
| 41. | SlowWolf | The Binding of Isaac: AB - Let's Play! 13 [Lilly] | 6 | Let's Play |
| 42. | SlowWolf | The Binding of Isaac: AB - Let's Play! 25 [Grit] | 6 | Let's Play |
| 43. | Beckymegan | Let's Play: The Binding of Isaac | Ep. 3 | 6 | Let's Play |
| 44. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 10 [Ultra Hard] | 5 | Let's Play |
| 45. | (OLD) BoomGoesMaximus | [LET'S PLAY] The Binding of Isaac: Part 1 / 3 | 5 | Let's Play |
| 46. | SlowWolf | The Binding of Isaac: AB - Let's Play! 36 [Orbital] | 5 | Let's Play |
| 47. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 23 [Stamina] | 5 | Let's Play |
| 48. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 20 [Incremental] | 5 | Let's Play |
| 49. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 24 [Despair] | 5 | Let's Play |
| 50. | SlowWolf | The Binding of Isaac: AB - Let's Play! 12 [Greedy] | 4 | Let's Play |
| 51. | SlowWolf | The Binding of Isaac: AB - Let's Play! 37 [Lookalike] | 4 | Let's Play |
| 52. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 26 [Glutton] | 4 | Let's Play |
| 53. | LaidBack Gaming Network | Let's Play: Fingered [PC/Steam] | 4 | Let's Play |
| 54. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 15 [99%] | 4 | Let's Play |
| 55. | SlowWolf | The Binding of Isaac: AB - Let's Play! 30 [Temperance] | 4 | Let's Play |
| 56. | SlowWolf | The Binding of Isaac: AB - Let's Play! 40 [Scattered] | 4 | Let's Play |
| 57. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 25 [Flagellation] | 4 | Let's Play |
| 58. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 08 [Aprils Fool] | 4 | Let's Play |
| 59. | Noise Berry Games | SerJonPlays: Binding Of Isaac: Episode 2: A Go With Cain | 4 | Let's Play |
| 60. | SlowWolf | The Binding of Isaac: AB - Let's Play! 32 [Misnomer] | 4 | Let's Play |
| 61. | SlowWolf | The Binding of Isaac: AB - Let's Play! 07 [HOHOHOHO] | 4 | Let's Play |
| 62. | Christonian | Roguelike Friday - Faron's Fate | 3 | Let's Play |
| 63. | SlowWolf | The Binding of Isaac: AB - Let's Play! 14 [Caint] | 3 | Let's Play |
| 64. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 21 [Babied] | 3 | Let's Play |
| 65. | (OLD) BoomGoesMaximus | [LET'S PLAY] The Binding of Isaac: Part 2 / 3 | 3 | Let's Play |
| 66. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 45 [Extra Strong Vanilla] | 3 | Let's Play |
| 67. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 48 [Bookend] | 3 | Let's Play |
| 68. | vixensmiles89 | Let's Play With Vix - The Binding Of Isaac | 3 | Let's Play |
| 69. | SlowWolf | The Binding of Isaac: AB - Let's Play! 39 [Bombastic] | 3 | Let's Play |
| 70. | SlowWolf | The Binding of Isaac: AB - Let's Play! 27 [Persian] | 3 | Let's Play |
| 71. | SlowWolf | The Binding of Isaac: AB - Let's Play! 15 [Skimming] | 3 | Let's Play |
| 72. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 13 [Baby Steps] | 3 | Let's Play |
| 73. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 14 [Victory Lap] | 3 | Let's Play |
| 74. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 12 [Discovery] | 3 | Let's Play |
| 75. | TheNoidBag | The Binding of Isaac - Episode 6 [Disappointing] | 2 | Let's Play |
| 76. | (OLD) BoomGoesMaximus | [LET'S PLAY] The Binding of Isaac: Part 3 / 3 | 2 | Let's Play |
| 77. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 16 [Fool's Gold] | 2 | Let's Play |
| 78. | Snoozzzalot | Best Death...Or the Worst? Snooze Plays Binding of Isaac | 2 | Let's Play |
| 79. | SlowWolf | The Binding of Isaac: AB - Let's Play! 35 [Kidney Stone] | 2 | Let's Play |
| 80. | SlowWolf | The Binding of Isaac: AB - Let's Play! 29 [Training Wheels] | 2 | Let's Play |
| 81. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 40 [IncreMental] | 2 | Let's Play |
| 82. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 46 [Hohum] | 2 | Let's Play |
| 83. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 39 [Insanity] | 2 | Let's Play |
| 84. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 35 [Off Rocker] | 2 | Let's Play |
| 85. | TheNoidBag | The Binding of Isaac - Episode 16 [Inevitability] | 2 | Let's Play |
| 86. | SlowWolf | The Binding of Isaac: AB - Let's Play! 31 [Blindsided] | 2 | Let's Play |
| 87. | SlowWolf | The Binding of Isaac: AB - Let's Play! 34 [Sluggish] | 2 | Let's Play |
| 88. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 09 [Pokeymans] | 2 | Let's Play |
| 89. | Johnyliltoe | Let's Play The Binding Of Isaac - Isaac Run Part 1 | 2 | Let's Play |
| 90. | TheNoidBag | Six Ways to Sunday: The Binding of Isaac Community Remix Mod - Friday | 1 | Let's Play |
| 91. | vixensmiles89 | Let's Play with Vix - The Binding of Isaac "Samson is OP!" | 1 | Let's Play |
| 92. | TheNoidBag | The Binding of Isaac - Episode 15 [So Close] | 1 | Let's Play |
| 93. | MienRogue | MIENROGUE - Binding of Isaac Playthrough part 5 | 1 | Let's Play |
| 94. | swamperplays | The binding of Isaac Wrath of the lamb Let's Play 1 | 1 | Let's Play |
| 95. | Let's Play The World! | Let's Play Live! - The Binding of Isaac - Semi-Secret Test Stream | 1 | Let's Play |
| 96. | SlowWolf | The Binding of Isaac: AB+ - Let's Play! 44 [Rebound] | 1 | Let's Play |
| 97. | TheNoidBag | The Binding of Isaac - Episode 9 [Cessy's Curse] | 1 | Let's Play |
| 98. | swamperplays | The binding of Isaac Wrath of the lamb Let's play ep 5 | 1 | Let's Play |
| 99. | Let's Play The World! | Let's Play! - Steam Roll - 6 - The Binding of Isaac | 1 | Let's Play |
| 100. | MienRogue | MIENROGUE - Binding of Isaac Playthrough part 1 | 1 | Let's Play |
