| 2025-06-07 |  N4meless24 | This Is The RAREST Run I've Ever Had! | The Binding Of Isaac Road To Dead God. | 0:00 | 290 |
| 2025-06-05 | N4meless24 | This Is The LUCKIEST Run You'll Ever See! | The Binding Of Isaac Road To Dead God. | 0:00 | 430 |
| 2025-05-24 | N4meless24 | Getting The HARDEST Achievement In Isaac: #shorts #gaming #isaac #tboi #achievement | 0:00 | 6,580 |
| 2025-05-24 | JuampaZx | TODOS los Jefes de The Binding of Isaac en una Sola PARTIDA | 0:00 | 21 |
| 2025-05-23 | Z3r0fficial | My friend is a Singer #shorts #thebindingofisaac | 0:00 | 992 |
| 2025-05-21 | I Termosifoni | Finisce Qua. - The Binding Of Isaac [co-op] | 0:00 | 7,177 |
| 2025-05-10 | TheGuercio85 | The Binding of Isaac: la run più bella che io abbia mai fatto | 0:00 | 23 |
| 2025-04-30 | Exa | The Binding of Isaac: Chaos Run with Cain VS DELIRIUM | 0:00 | 3 |
| 2025-04-22 | FullmetalRoccia | Blade Strangers: per il mio amico fan di The Binding of Isaac | 0:00 | 6 |
| 2025-04-20 | l_TheOblivion_l | The Bindind of Isaac | 0:00 | 31 |
| 2025-04-14 | Forretress Creations | Live reaction dell'Ignoto su Isaac | 0:00 | 12 |
| 2025-01-30 | Ven's Random Footage | The Binding of Isaac [524] - An out of control switch | 0:00 | 5 |
| 2025-01-14 | Arcadia Café | MINECRAFT incontra THE BINDING OF ISAAC e DOOM!? #shorts #videogiochi #indiegame | 0:00 | 1,422 |
| 2025-01-09 | I Termosifoni - Live Twitch | Finalmente Isaaccone Online | The Binding of Isaac [ !instant - !giveaway - !ferta ] | 0:00 | 2,008 |
| 2024-12-24 | Nebraska94 | Giusespi il ricattatore #gaming #thebindingofisaac #repentance | 0:00 | 24 |
| 2024-12-11 | Play2it | The Binding of Isaac: Repetance+Beta | gameplay (PC videogame) | 0:00 | 25 |
| 2024-11-26 | Bandrum_ | Tutti nel sotterraneo - The Binding of Isaac | 0:00 | 10 |
| 2024-11-19 | Lyo The Wolf | THE BINDING OF ISAAC GAMEPLAY #2 - SBLOCCHIAMO MAGDALENE E DEI NUOVI POTERI | 0:00 | 5 |
| 2024-11-16 | demone blu | Ho Raggiunto l'INFINITY % su The Binding of Isaac | 0:00 | 2,819 |
| 2024-11-08 | RedFlameFox | Binding of Isaac - Doppiato in ITALIANO da un IA | 0:00 | 434 |
| 2024-11-02 | N4meless24 | How To Progress In The Binding Of Isaac Explained: | 0:00 | 1,531 |
| 2024-10-28 | Lyo The Wolf | THE BINDING OF ISAAC GAMEPLAY #1 - L'INIZIO DI TUTTO | 0:00 | 13 |
| 2024-10-23 | N4meless24 | 10 Minutes of Useless Information About The Binding Of Isaac. | 0:00 | 2,732 |
| 2024-10-22 | Ven's Random Footage | The Binding of Isaac [504] - Beastly Betrayal | 0:00 | 6 |
| 2024-10-16 | ilvolacchio | PROBLEMI SU THE BINDING OF ISAAC #tboi #isaac | 0:00 | 2,257 |
| 2024-10-01 | IreneKitty - Gaming | Dobbiamo sbloccare Tainted Bethany - The Binding of Isaac ITA #01 | 0:00 | 11 |
| 2024-09-27 | IreneKitty - Gaming | 16 anni incinta simulator! - The Binding of Isaac [Only Tainted Lillith] #01 | 0:00 | 16 |
| 2024-09-24 | IreneKitty - Gaming | Cerchiamo di sbloccare un Tainted! - The Binding of Isaac ITA | 0:00 | 65 |
| 2024-09-23 | JuampaZx | The Binding of Isaac Obra Maestra | 0:00 | 164 |
| 2024-09-17 | IreneKitty - Gaming | Impariamo a ballare con The Lost + Sconfiggiamo The Mother - The Binding of Isaac ITA | 0:00 | 18 |
| 2024-09-16 | IreneKitty - Gaming | Dobbiamo andare nel corpo di mamma mamma! - The Binding of Isaac ITA | 0:00 | 63 |
| 2024-09-12 | IreneKitty - Gaming | Blu baby è una merda tumefatta - The Binding of Isaac ITA | 0:00 | 14 |
| 2024-09-10 | IreneKitty - Gaming | Raggiungiamo la cattedrale oscura! - The Binding of Isaac ITA | 0:00 | 19 |
| 2024-09-06 | IreneKitty - Gaming | Abbiamo battuto Hush, giù per il tubo! - The Binding of Isaac ITA | 0:00 | 9 |
| 2024-09-04 | IreneKitty - Gaming | FINALMENTE! HUSH A 90 GRADI!!! - The Binding of Isaac ITA | 0:00 | 8 |
| 2024-08-29 | IreneKitty - Gaming | Bethaaaaaaaany! - The Binding of Isaac ITA | 0:00 | 6 |
| 2024-08-27 | IreneKitty - Gaming | Proviamo Bethany! - The Binding of Isaac ITA | 0:00 | 6 |
| 2024-08-26 | IreneKitty - Gaming | Siamo ridicoli come Isaaaaac! - The Binding of Isaac ITA | 0:00 | 2 |
| 2024-08-23 | IreneKitty - Gaming | Ho capito come raggiungere Hush! - The Binding of Isaac ITA | 0:00 | 6 |
| 2024-08-15 | IreneKitty - Gaming | Dobbiamo avere fortuna! The Binding of Isaac ITA | 0:00 | 7 |
| 2024-08-12 | IreneKitty - Gaming | Isacco infame per te solo lame - The Binding of Isaac ITA | 0:00 | 5 |
| 2024-08-12 | Pinstolfo & B3rrytv | Isaac reference #thebindingofisaac #memes | 0:00 | 378 |
| 2024-08-07 | IreneKitty - Gaming | Isacco è sfigato come il sottoscritto - The Binding of Isaac ITA | 0:00 | 7 |
| 2024-08-06 | IreneKitty - Gaming | Ritorno su Isaac, ma davvero? - The Binding of Isaac ITA | 0:00 | 412 |
| 2024-08-04 | IlBarba Adventures | Almond milk Bloopers #gaming #steam #gameplay #games #perte #pixelart #thebindingofisaac #bloopers | 0:00 | 27 |
| 2024-08-03 | Zetta Punk Videogamer | EDMUND MCMILLEN - DESIGNER DA CULTO | 0:57 | 85 |
| 2024-07-19 | Pinguz98 | ISAAAAAAC! Ma Pinguz è sparito @markbum @irenekitty | 57:34 | 4 |
| 2024-07-19 | TheGuercio85 | Facciamoci qualche Partitella ad Isaac | 0:00 | 6 |
| 2024-07-16 | ye west | PRIMA LIVE the binding of isaac | 28:22 | 35 |
| 2024-07-05 | Pinguz98 | Il rimborso di Monstrum, il finale storto di Cakey's e The Binding of Isaac!! @irenekitty @markbum | 2:23:09 | 12 |
| 2024-07-02 | YAZURAMA | LIVESTREAM - THE BINDING OF ISAAC, BETANIA E' POCO DIVERTENTE... | 2:21:18 | 35 |
| 2024-06-24 | YAZURAMA | TWITCH LIVESTREAM - Il ritorno di Lazaruma: The Binding Of Isaac | 2:10:08 | 28 |
| 2024-06-20 | FUNKY TACO | The Binding of Deuterio #091 - Pure evilness | 18:18 | 11 |
| 2024-06-19 | FUNKY TACO | The Binding of Deuterio #096 - | 1:00:41 | 5 |
| 2024-06-03 | FUNKY TACO | The Binding of Deuterio #089 - MegaSatana, la puttana della porta accanto | 1:50:26 | 22 |
| 2024-05-29 | FUNKY TACO | The Binding of Deuterio #087 - Vomito sangue su Satana | 51:08 | 11 |
| 2024-05-28 | Kuro Naeda | "SONO POVERO" - Twitch Clips | 0:11 | 473 |
| 2024-05-24 | FUNKY TACO | The Binding of Deuterio #085 - | 24:24 | 26 |
| 2024-05-22 | FUNKY TACO | The Binding of Deuterio #084 - Besthiany | 29:47 | 47 |
| 2024-05-20 | FUNKY TACO | The Binding of Deuterio #083 - Toxic run | 54:56 | 14 |
| 2024-05-08 | FUNKY TACO | The Binding of Deuterio #078 - Nothing happened | 33:48 | 52 |
| 2024-05-06 | FUNKY TACO | The Binding of Deuterio #077 - Mi sono eccitato | 33:25 | 64 |
| 2024-05-03 | Indiegamecast | #Mesindie: consigli di Aprile 2024 | 20:13 | 197 |
| 2024-04-17 | Bored Lamp I | Facciamo Cadere Proiettili tipo The Binding of Isaac | 1:19 | 635 |
| 2024-04-17 | manimolle | ISAAC ABBIAMO TANTO DA IMPARARE | THE BINDING OF ISAAC #1 | 38:34 | 97 |
| 2024-04-07 | Bored Lamp I | Sviluppo The Binding of Isaac da 0? (magari) | 2:46 | 1,119 |
| 2024-04-02 | ScaryCarpet | 1-Minute Game Review - The Binding of Isaac #gaming #review #shorts | 1:00 | 1,160 |
| 2024-03-15 | VKTRJ VOD | Mi faccio la madre per la SECONDA volta stando FERMA | VKTRJ VOD | 1:11:53 | 86 |
| 2024-03-14 | Crappo Live | CREEPY e SUO FRATELLO GIOCANO A THE BINDING OF ISAAC E SI BLASTANO | 2:05:10 | 1,423 |
| 2024-03-13 | Marant99 | When you are too greedy on The Binding of Isaac.. | 2:30 | 20 |
| 2024-03-12 | VKTRJ VOD | Sconfiggo la madre per la prima volta su the Binding of Isaac | VKTRJ VOD | 1:29:40 | 158 |
| 2024-03-09 | mikundead88 | 🔴Live questa sarà una lunga live (se la wi-fi permette) pt2 | 3:27:52 | 10 |
| 2024-03-05 | mikundead88 | 🔴Live the binding of isaac vediamo di fare qualcosa | 3:35:20 | 10 |
| 2024-02-26 | VKTRJ VOD | Questo gioco mi farà venire i traumi - The binding of Isaac | VKTRJ VOD | 1:49:14 | 128 |
| 2024-01-30 | ThomasBW_ | THE BINDING OF ISAAC, MA SONO UN INCAPACE - ThomasBW_ | 18:11 | 36 |
| 2024-01-30 | Leonik | Tocca salvare la mamma di Isaac | 1:35:07 | 28 |
| 2024-01-27 | Gaccio's vod | the binding of Isaac | from 0% to dead god - part 8 | 1:53:29 | 2 |
| 2024-01-17 | Streghetta Channel | The Binding Of Isaac | 1:00:57 | 10 |
| 2024-01-15 | FUNKY TACO | The Binding of Deuterio #075 - Un Crecs | 41:34 | 45 |
| 2024-01-06 | Leonardo Alfaioli | THE BINDING OF ISAAC MA SE PRENDO DANNO IL VIDEO FINISCE #bindingofisaac | 0:52 | 1,026 |
| 2024-01-01 | FUNKY TACO | The Binding of Deuterio #072 - Hush anche io | 54:29 | 99 |
| 2023-12-08 | FUNKY TACO | The Binding of Deuterio #063 - Negativo | 1:01:18 | 77 |
| 2023-12-06 | Auxoar Gaming | GIOCHIAMO AD ISAAC/ E CONTROLLIAMO I GIOCHI DEI GAMES AWARDS | 2:16:00 | 18 |
| 2023-11-13 | Pinstolfo & B3rrytv | damn #isaac #tboi #thebindingofisaac #thebindingofisaacrepentence | 0:12 | 165 |
| 2023-11-10 | FUNKY TACO | The Binding of Deuterio #052 - Rompo leggermente la greed | 44:23 | 65 |
| 2023-11-03 | mikundead88 | 🔴Live the binding of isaac il ritorno dopo na fracca de tempo | 1:39:05 | 4 |
| 2023-10-25 | FUNKY TACO | The Binding of Deuterio #045 - Top 10 imbecilli: io | 44:42 | 28 |
| 2023-10-25 | PsyQ_SeBa | un po di isaac | 52:52 | 22 |
| 2023-10-18 | FUNKY TACO | The Binding of Deuterio #042 - Random run + challenge | 23:58 | 70 |
| 2023-10-09 | FUNKY TACO | The Binding of Deuterio #038 - Lilhit | 28:32 | 5 |
| 2023-10-01 | EnderGaming | "Storia di un Isacco veramente Sfortunato" | 7:43 | 165 |
| 2023-09-22 | ScaryCarpet | 7 FAQ For The Binding Of Isaac - Let's FAQ | 8:10 | 504 |
| 2023-09-08 | FUNKY TACO | The Binding of Deuterio #025 - Caino e Bumbo tag team | 52:09 | 46 |
| 2023-09-07 | Auxoar Gaming | PROVO LA GREED MODE PER LA PRIMA VOLTA the binding of isaac ita | 7:31 | 47 |
| 2023-08-21 | FUNKY TACO | The Binding of Deuterio #017 - Eva cca cosa ho fatto | 39:48 | 42 |
| 2023-08-09 | mikundead88 | 🔴Live the binding of isaac devo ricominciare da capo | 2:25:58 | 4 |
| 2023-08-04 | FUNKY TACO | The Binding of Isaac #010 - Mi incazzo parecchio | 26:28 | 23 |
| 2023-08-04 | KirouLIVE | SCAMMATOOO?!?? | #twitch #twitchitalia #bindingofisaac | 0:18 | 589 |
| 2023-07-30 | Spelly | me singing all eyes on me while playing the binding of isaac | 5:46 | 285 |
| 2023-07-29 | N4meless24 | These Bosses Had NO CHANCE | 23:02 | 3,472 |
