| 1. |  UberDanger | 1,772,124 | The Binding of Isaac Afterbirth+ review | 15:47 |
| 2. | jam | 550,257 | ISAAC ONLINE RAAAAAH | 0:00 |
| 3. | Lasse Vestergaard | 111,365 | Jeg vender TILBAGE og er OP! | Highlights: Isaac REBIRTH | 13:18 |
| 4. | MythyMoo | 58,657 | I Played THE BINDING OF ISAAC: REBIRTH For The First Time Ever | 20:51 |
| 5. | Mewkel_ | 24,922 | KÆFT HAN ER TYK! (Binding of Isaac Rebirth) - Mewkel | 11:34 |
| 6. | Oliver As Latias | 7,248 | Meanwhile on The Binding of Isaac (Steam Remote Play) | 5:14 |
| 7. | Amonday | 3,481 | Bethany | The Binding of Isaac Antibirth - Speedpaint | 4:23 |
| 8. | Molle | 3,325 | VELKOMMEN TILBAGE (DRUK) STREAM! | 2:44:45 |
| 9. | Davidkonsta | 3,017 | I should NOT have said that...... #shorts | 0:23 |
| 10. | Madi Renai | 1,954 | [Let's Play] Isaac: Afterbirth - #43 Normal Hard | 59:38 |
| 11. | PlayStation Nordic | 1,570 | PS Plus | Your monthly games for November 2014 | 1:57 |
| 12. | LokeHansen | 977 | The Binding of Isaac Rebirth Afterbirth #8 | RAGE - So insane shots and progress | 43:46 |
| 13. | FreakyFreddysCaveOfWonder | 803 | The Binding Of Isaac Repentance (part 31) | 0:00 |
| 14. | Scribbs | 583 | This is Your Life Now [INDIE GAME] | Existential Crisis The Game? | 12:11 |
| 15. | BeeVeelutions Twitch Archive | 389 | Random Isaac Run Compilationes | 11:32 |
| 16. | Invenblocker | 333 | Mega Satan Save | 1:04 |
| 17. | Daniel9129 | 309 | Isaac Repentance First To 5 WINSTREAK!!! PART 2 | TBOI: Repentance | 0:00 |
| 18. | LordsofCatz | 288 | The Binding of Isaac Afterbirth + - Victory Run | 44:18 |
| 19. | GametestDanmark | 114 | Binding of Isaac - Afterbirth | Anmeldelse | 4:09 |
| 20. | SolVezon | 113 | Reto si muero se acaba el video 1# | The Binding Of Isaac Repentance | primer intento | 11:29 |
| 21. | Efterspillet | 108 | Ventetiden er overstået! | Binding of Isaac: Repentance | 49:23 |
| 22. | Linnet's How To | 79 | How to Disable Auto Center Camera in Wildstar | 0:12 |
| 23. | TwiceBanned | 57 | Oli-Chan approved Supercut | 7:25 |
| 24. | ThatInsaneDane | 49 | Dane Plays: The Binding of Isaac [P1] | 50:31 |
| 25. | Sean N. | 42 | Binding of Isaac Afterbirth - Being bad at it #4 (with bad sound!) | 1:10:32 |
| 26. | Halendir The Dane | 36 | Feral Fury - Dansk Anmeldelse | 6:28 |
| 27. | Ulvra Silvershade | 34 | Silvershade Gaming - Halloween Stream | 4:00:26 |
| 28. | MrMasoes | 32 | This game is creepy... The Binding of Isaac [30fps 772p] | 27:56 |
| 29. | Tereith | 32 | Tereith's big ramble - Important - Binding of Isaac gameplay | 10:30 |
| 30. | Ramdolph Oppalot Gaming | 24 | The binding of Isaac #6 (Gamish Drunk) | 16:44 |
| 31. | Rab(BIT)ie | 23 | Back with a new look and back to Isaac | 40:37 |
| 32. | calamity | 23 | [The Binding of Isaac - Afterbirth] Ultra Greed fight with 99 coins | 4:49 |
| 33. | AwesomeDemon | 16 | gotta kill Satan - The Binding of Isaac: Afterbirth+ | 1:03:01 |
| 34. | McOeko | 13 | The Binding of Isaac Rebirth. a new part in the adventure | 39:24 |
| 35. | Malediction | 12 | Another Day Another Unlock! Binding Of Isaac Repentance #4 | 41:32 |
| 36. | CowenT | 10 | Binding of Isaac: Rebirth - 2 hit MoMs hearth | 4:17 |
| 37. | Niessuh | 10 | Steam Top 10 Rated Games All-Time | 2:16 |
| 38. | Ankford | 7 | HELL HAS LOTS OF TEARS | The Binding Of Isaac: Rebirth | ONE-OFF | 35:33 |
| 39. | BB Steam Review | 7 | The Binding of Isaac: Repentance Live stream thing | 15:56 |
| 40. | BP_DM - VODs | 5 | BP_DM | The Biniding of Isaac + Amnesia: Rebirth | Full Stream | 3:41:56 |
| 41. | Danish Craft | 4 | Jeg spiller Isaac | 31:12 |
| 42. | Lundoff | 4 | IS THIS THE RUN? - The Binding of Issac Rebirth | 0:00 |
