| 3 days ago |  Lusaffa | 1,800 | August 03 2025 - Binding Of Isaac Repentance Daily | 0:00 |
| 4 days ago | jamzy | 648 | The Binding Of Isaac Afterbirth+ LIVE #84 - Can magdalene be fast? | 0:00 |
| 6 days ago | The Great Berate | 13,300 | Lo-fi Eden Streaking to play Binding Of Isaac to | 0:00 |
| 2025-07-30 | JAY SHADE | 4,940 | 🔴 KILLING MOTHERS HEART! | The Binding Of Isaac Repentance + | 0:00 |
| 2025-07-21 | ItsTheMattC | 2,070 | Why You NEVER Sleep On Chaos: | 0:00 |
| 2025-07-18 | TheTurtleMelon | 13,900 | I Made So AWFUL Explosive Mistakes In Modded Isaac! | 0:00 |
| 2025-07-08 | Miss Meggiecat | 186 | This Took Me 70+ Attempts 🫠 #shorts #gaming #thebindingofisaac #twitch | 0:00 |
| 2025-07-06 | Dahlia Starbright | 1,030 | ✨ Fallen Star Is Once Again Binding Isaac ✨ (26/08/2024) | 0:00 |
| 2025-06-25 | RossBoomsocks | 799,000 | I Got To Choose ANY ITEM At The Start Of The Run, And Then I FLATTENED Delirium | 0:00 |
| 2025-06-22 | VirtualGhost | 908 | Can I Survive The Hardest Isaac Run Ever? | 0:00 |
| 2025-06-18 | Mavis Masaki | 516 | STARTING ISAAC ALL OVER AGAIN... | The Binding of Isaac: Repentance | Mavis Masaki ENVtuber | 0:00 |
| 2025-06-03 | Wizard II | 718 | MvM Gameplay Silentsky (Solo) The Beast's Return (Rematch) | 0:00 |
| 2025-06-02 | Mr Samuel Streamer 2 | 44,000 | Goodnight Sweet Isaac | Binding of Isaac Repentance #6 | 0:00 |
| 2025-06-01 | Super Space Squid | 1,870 | GOSH FREAKING DARN IT, I DID A VICTORY LAP, AGAIN!!!! - The Binding Of Isaac Repentance+ | 0:00 |
| 2025-05-29 | Joel MEGYC | 1,130 | I ain't giving up!!! - The Binding of Isaac Repentance (part 23) | 0:00 |
| 2025-05-21 | Old Wolf Apocalypse | 223 | Binding of Isaac for giggles Run 2, Azazel, Lilith and Judas. | 0:00 |
| 2025-05-15 | Rinnick | 1,160 | Bathany Vs Hush! | 0:00 |
| 2025-05-07 | Hanternos | 26,100 | Control me! | Binding of Isaac Repentance #vtuber | 0:00 |
| 2025-05-04 | Chuggaacrayz | 1,010 | Fool's Gauntlet Feed #1: NOT Tainted Lost to Beast in Repentance | 0:00 |
| 2025-05-01 | Harvologist | 847 | The Binding Of Isaac | just chilled, NO CAR TODAY. Maybe... | 0:00 |
| 2025-04-29 | GREEEG | 394 | Melting my Nintendo Switch with a million bone tears | 0:00 |
| 2025-04-24 | 🧩Jishy🧩 | 2,060 | 🔴The Binding of Isaaaaaac repentance + IS BACK!!🔴 | 0:00 |
| 2025-04-21 | Relieved | 252 | The Magdalene Video | 0:00 |
| 2025-04-14 | Madtedd0 | 437 | The run that lasted over 2 HOURS!!! - TBOI Repentance MULTIPLAYER [FULL VOD] | 0:00 |
| 2025-04-12 | TearofDisgrace | 85,200 | 🔴ToG🔴Marathon Panic, NIGHTMARE Timer, Isaac & Chill - Subathon S2 Pt101 | 0:00 |
| 2025-04-11 | K-I-Ler | 2,860 | Dad Beats Mum #bindingofisaac #dadvsmum #shortvideo | 0:00 |
| 2025-04-10 | Dude I'm Ash | 1,940 | 🔴 - Isaac Runs & RL | 0:00 |
| 2025-03-12 | Game on Drone on | 232 | Binding of Isaac Afterbirth + Repentence + | 0:00 |
| 2025-03-11 | JimShady | 1,200 | 🔴LIVE - New save to Dead God part 25 - The Binding of Isaac: Repentance Plus | 0:00 |
| 2025-02-26 | MigitMan03 | 267 | The Binding of Isaac: Repentance (with My Girl) /British/!commands//!convergent | 0:00 |
| 2025-02-19 | Flik's Gaming Stuff | 150,000 | Tues Feb 18th 2025: Isaac + ????? | 0:00 |
| 2025-02-16 | GAMER--SINCE1988 | 23 | Can i Beat?: The Binding of Isaac Afterbirth+ Part 3 on PlayStation 5 | 0:00 |
| 2025-02-16 | Wraith of Lambeg | 269 | Isaac the Egghead: Binding of Isaac #2 | 0:00 |
| 2025-02-14 | P1 Grinder | 7,050 | Binding of Isaac: Repentance – 2. High Brow | 0:00 |
| 2025-02-10 | Phoenixclaw | 85,600 | این گیم راجب مادریه که میخواد پسرشو با چاقو بکشه ⛔ | 0:00 |
| 2025-02-10 | gamezplay | 112,000 | Luck be a Landlord Roguelite Deckbuilder Spins to Win video game | 0:00 |
| 2025-01-25 | JVK3L3 | 334 | Can I Beat The Binding Of Isaac? | 0:00 |
| 2025-01-12 | CallumTheShogun | 6,540 | RLCS Later Today! | Binding of Isaac & Rocket League | 0:00 |
| 2024-12-31 | Tundrarich | 15,600 | I WANT MEGA MUSH | 18+ | 0:00 |
| 2024-12-29 | serenegeneration | 126 | the completionist saga: the binding of isaac ep 2 | 0:00 |
| 2024-12-22 | BlackAxon | 418 | The Binding of Isaac Repentance #124 Hi Again | 0:00 |
| 2024-12-22 | SomeGamingFan | 6,260 | Apollyon: Isaacs Forgotten Child | 0:00 |
| 2024-12-19 | YungPitLord | 1,830 | I'm back | 0:00 |
| 2024-12-13 | Koto And Spacey | 774 | Testing My Knowledge of The Binding of Isaac: Repentance | 0:00 |
| 2024-12-07 | callumsmile | 12,200 | Back To The Binding Of Isaac AGAIN | 0:00 |
| 2024-12-05 | Welham's World | 529 | Roguelite/ Roguelike Chaos! | 0:00 |
| 2024-12-01 | RobotNinjaUK | 290 | Binding of Isaac rebirth | 0:00 |
| 2024-12-01 | Chaotix | 44,200 | The Binding of Isaac: Repentance (Multiplayer!) | Advent Chaolendar 2024 [DAY 2] | 0:00 |
| 2024-11-26 | Ricep0t | 140 | Binding of Isaac | 0:00 |
| 2024-11-22 | CRNK | 255 | The NEW Isaac Multiplayer is a MOVIE! | 0:00 |
| 2024-11-22 | Zantor | 2,009 | We Completely Broke Binding of Isaac's New Online Mode #shorts | 0:00 |
| 2024-11-21 | DarkSpiritK | 1,390 | The Binding of Isaac Repentance Plus #1 // Winning An Online Daily Run | 0:00 |
| 2024-11-04 | McYawgi | 500 | [🔴ENG] Binding of Isaac newbie - we're getting better!| Best stream on the internet :D | 0:00 |
| 2024-11-01 | Just Flawless | 1,440 | I Can Become A Furry In TBOIR? | 0:00 |
| 2024-10-30 | AutumnHaunted | 331 | Random Isaac Runs Stream (w/ Bikdip, 2024/10/06) | 0:00 |
| 2024-10-11 | SlimSanta94 | 165 | The Binding of Isaac - Dead God Trophy Unlocked | 0:00 |
| 2024-09-22 | Nightmare Gaming | 343 | ♾️ Infinity % #thebindingofisaac #repentance #gaming | 0:00 |
| 2024-09-21 | Panda King Pinder | 48 | Random Binding of Isaac Rebirth - 21.09.2024 | 0:00 |
| 2024-09-02 | El Gato Diablo | 805 | The Binding of Isaac: Rebirth - Whatever this is | 0:00 |
| 2024-08-28 | GAMING WORLD NETWORK | 3,290 | RUN SAUSAGE RUN TROPHY CANNIBAL PLAYSTATION 5 #playstationtrophy #achievement #steam #switch | 0:00 |
| 2024-08-19 | KAOS | 875 | PLAYING AS EVE TO GET ALL COMPLETION MARKS PART 8 THE BINDING OF ISAAC | 0:00 |
| 2024-08-16 | WesTheHunter | 820 | My First Double Stream - The Binding Of Isaac Repentance (2) | 0:00 |
| 2024-08-12 | Randonlyh | 1,120 | The Binding of Isaac: Flash Vs Repentance | 0:00 |
| 2024-08-03 | Ruri Chan EN | 702 | WHY IS THERE SO MANY BUGS | The Binding of Isaac - Tainted Lost to Home | 5:59 |
| 2024-07-31 | Nexus Entertainment | 507 | Crypt Custodian [Release Date Announcement Trailer | PS5 & PS4 | Xbox | Steam] | 0:56 |
| 2024-07-28 | Luna Bold, the Full Bold Streams | 197 | Cain becomes death destroyer of all and finishes his run - Binding of Isaac Repentance | 1:26:25 |
| 2024-07-25 | iHenpie | 606 | #platinum #popper #trophyhunter #playstation #gaming #shorts | 0:24 |
| 2024-07-03 | SneeKy_SnacK | 141 | Daily Run Livestream! - The Binding Of Isaac: Repentance | 36:17 |
| 2024-06-19 | AHF Best Gaming | 62 | Binding of Isaac but... I always have mega mush! | 16:11 |
| 2024-05-30 | Elise and Sam | 18,100 | We Are All Victims of Entropy In the End | Background Noise #3 | 37:55 |
| 2024-05-29 | Andolono | 647 | What do You Give the Girl Who has Everything? - The Binding of Isaac: Repentance - Part 361 | 45:47 |
| 2024-05-20 | Vicksy | 20,800 | lost at menu screen 💀 #vtuber #vtuberen | 0:23 |
| 2024-05-09 | Mr Swift Plays | 51 | Isuck | 1:07:02 |
| 2024-05-08 | Butler063 | 717 | Time for some randomness with Crowd Control! | 2:51:12 |
| 2024-05-06 | Deez Games | 9,140 | Can I Beat The Binding Of Isaac Rebirth On My First Ever Play? | 33:24 |
| 2024-05-05 | Doodleboat | 48 | epic isaac moment | 0:08 |
| 2024-05-02 | JMC Streams | 305 | Last Stream before Exams | 39:34 |
| 2024-04-29 | Northernlion's Egg Carton | 4,040 | 🥭 Northernlion has a moment of Awakening 🥭 | 0:54 |
| 2024-04-10 | Atlus | 772 | The Binding of Isaac: Repentance Edit | Jesus Loves Me | 1:33 |
| 2024-04-09 | Endersmithgamer | 706 | well i had fun on this#thebindingofisaacrebirth #funny #gaming #endersmithgamer | 0:22 |
| 2024-04-02 | Piece of Pie LIVE | 1,310 | The Binding of Isaac: Repentance (2024.02.26) | 1:04:21 |
| 2024-03-30 | Docy93 | 5,650 | Isaac Unlocks 494/637 - Binding of Isaac Repentance | 3:01:47 |
| 2024-03-13 | FrozenMelon | 179 | Binding Of Issac - Money And Friends | 36:53 |
| 2024-03-12 | BritMachine | 2,320 | Oh that's Bumbino. That's Bumbino in my Greed mode run. #bindingofisaac | 0:34 |
| 2024-03-12 | Captain Eggcellent Clips | 6,050 | More games need cheat codes! #gaming | 0:18 |
| 2024-03-05 | thedragonreaper | 319 | looks like your goose is cooked me old sunshine | 2:18:45 |
| 2024-02-25 | RisanStar | 925 | Tainted Jacob Should Be Easy | 5:00 |
| 2024-02-24 | BailleLIVE | 63 | " Ok Winnable " | baille on #Twitch | 0:07 |
| 2024-02-21 | Masterath Gaming | 3,050 | Let's Play The Binding of Isaac: Repentance part 73/73: To the Final Promised Land! | 14:33 |
| 2024-02-08 | kaedesmith | 106 | What even is a win anyway? - The Binding of Isaac Repentance Episode 8 | 27:52 |
| 2024-02-04 | Skoldire | 21,600 | The Binding of Isaac : Repentance - Crowd Control - LIVE - Interact with the game live! | 3:31:33 |
| 2024-02-02 | Dark WolfHeart | 394 | Diving into hell | The Binding of Isaac Rebirth | Live @6pm GMT | 2:08:20 |
| 2024-01-22 | Jaccy | 454 | I Need YOUR Help! - The Gloaming: An Isaac Experience Inspired By The Fiend Folio Mod! | 1:53 |
| 2024-01-21 | Piece of Pie Software | 9,350 | Drak's Gaming - The Binding of Isaac: Repentance [Run 3] | 1:10:32 |
| 2024-01-06 | Silver Gaming Network | 2,650 | Oni - Anniversary Edition - Part 1 (Silver Gaming Network) | 2:56:37 |
| 2024-01-04 | Jamiesauce12 | 1,160 | The Binding of Isaac Rebirth (2) - Sheer Ineptitude | 22:10 |
| 2023-12-30 | BobbV | 426 | Fire away | Rheum | 8:43 |
| 2023-12-24 | ORCBUSTERX | 3,270 | Binding Of Isaac I Got So Close To Beating The Boss | 30:00 |
| 2023-12-21 | Dino_Roar Gaming | 1,060 | Draco D - Full Unedited Platinum Trophy Walkthrough (PS4/PS5) | 4:19 |
| 2023-12-09 | Luk & Lok | 495 | Lucky Dip || Binding of Isaac: Rebirth and Slay the Spire | 2:51:51 |
