| 1. |  G.O.T Games | First Time Hearing Twenty One Pilots "Guns For Hands" REACTION | 273 | |
| 2. | Andy Hillier Guitar Channel | Twenty One Pilots - Saturday Guitar Tutorial | 30 | Tutorial |
| 3. | Evilcorkin Reacts | AMAZING! - Diana Ankudinova - TRUCE - Twenty One Pilots - Cover - REACTION | 29 | |
| 4. | Beepminer | twenty one pilots - Clancy (FULL ALBUM REACTION) | 25 | |
| 5. | Andy Hillier Guitar Channel | How to play twenty one pilots Level of Concern Guitar Lesson | 20 | Tutorial |
| 6. | Andy Hillier Guitar Channel | Twenty One Pilots Shy Away Guitar Tutorial | 20 | Tutorial |
| 7. | Trophy Reacts | Twenty One Pilots - 'Jumpsuit' Official Video Reaction | 17 | |
| 8. | Andy Hillier Guitar Channel | How to Play Twenty One Pilots Choker Guitar Tutorial Lesson | 13 | Tutorial |
| 9. | Trophy Reacts | Twenty One Pilots - 'Nico and the Niners' Official Audio Reaction | 13 | |
| 10. | Beepminer | twenty one pilots - Next Semester (REACTION) | 12 | |
| 11. | Trophy Reacts | Twenty One Pilots 'Levitate' Official Music Video Reaction | 12 | |
| 12. | Slow Easy Piano Tutorials by Dario | Twenty One Pilots - Neon Gravestones (SLOW EASY PIANO TUTORIAL) | 10 | Tutorial |
| 13. | Flying Buttress | Warcraft [Dawn of the Aspects] - Chapter Twenty One (Part 2) | 9 | |
| 14. | Flying Buttress | Warcraft [Dawn of the Aspects] - Chapter Twenty One (Part 1) | 7 | |
| 15. | Xplanet | twenty one pilots - My Blood Reaction (MUST SEE!! BEST REACTION EVER!) | 6 | |
| 16. | sanic | Roblox Twenty One... | 5 | |
| 17. | Xplanet | Reacting to twenty one pilots: Levitate [Official Video] (MUST SEE!! BEST REACTION EVER!) | 5 | |
| 18. | GhostyGump | Twenty One Pilots Concert Experience - Out of Bounds Glitch | 5 | |
| 19. | Xplanet | Reacting to twenty one pilots: Nico And The Niners [Official Video] (BEST REACTION EVER!) | 4 | |
| 20. | Cam'sCamcorder | Ranking the Songs of Scaled and Icy 🐉 | A CATASTROPHE Commentary 🎵| Twenty One Pilots | Cam & Daisy | 4 | |
| 21. | Cam'sCamcorder | A Catastrophic 'Scaled and Icy' MEGAMIX 🐉 | CATASTROPHE 🎵 | Twenty One Pilots | Cameron & Daisy | 2 | |
| 22. | FateMediaNet | RB4 DLC Review: Twenty One Pilots Pack 01 (Guitar/Bass/Pro Drums) Rock Band Rivals | 2 | Review |
| 23. | Xplanet | Reacting to twenty one pilots: Jumpsuit [Official Video] (Not to sure about this one!) | 2 | |
| 24. | Sarethon | Let's Play LOTR: The Third Age Episode Twenty One: Find Dwarven Dragon Armor! | 1 | Let's Play |
| 25. | Spiider Playz | [EVENT] How to get the Twenty One Pilots Flag in Twenty One Concert Experience (Twenty One Pilots) | 1 | Guide |
| 26. | Xplanet | Twenty one Pilots - Chlorine Reaction! (WTF IS THAT!?🧐) | 1 | |
| 27. | Xplanet | Reacting to Twenty One Pilots: My Blood [Official Audio] (I Can Not Wait For The Video!) | 1 | |
