This is not one continuous attempt - I did it in three parts. First was pre-Stella/Loretta, then 13th Street to the double Frankenstein room, then double Frankenstein to the end of the game. As you'll see in the footage, I also made a fourth save state after the double Frankenstein room (out of rage), but I never actually reloaded from that state.
My normal runs were one character or the other, but on Hard Mode, using the strengths of both characters became necessary.
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Shovatar163 presently has 58,186 views for Castlevania: Portrait of Ruin across 18 videos, and roughly a days worth of Castlevania: Portrait of Ruin videos were uploaded to his channel. This is 10.85% of the total watchable video on Shovatar163's YouTube channel.