It is my favorite game at all times, and yes I've found the way to beat the final boss without any companions. I've use the perk sniper to cripple last boss limbs, and shot in his legs to slow him down. Also as some people said, it is not necessary to use big guns or energy weapons, if you have enough ammo for M72 Gauss Rifle or PPK12 Gauss Pistol, and you have proper perks to deal much damage, it should be enough to to complete a game. Sorry for low framerate, this game is not very good optimized (it is a GoG version).
At present, Blaze Rhodon has 993 views spread across 2 videos for Fallout 2, with his channel publishing less than an hour of Fallout 2 content. This is less than 0.04% of the total video content that Blaze Rhodon has uploaded to YouTube.