RNA interference (RNAi) holds great potential as a therapeutic agent for the treatment of human ....

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RNA interference (RNAi) holds great potential as a therapeutic agent for the treatment of human diseases and as a bicontrol agent for controlling pests in the agricultural fields. An experiment was conducted to study the use of 'RNAi' for the potential treatment of disorders of cholesterol metabolism. Some people possess genetic mutations with elevated levels of 'ApoB' gene which predisposes them to coronary artery diseases.Lowering the amount of 'ApoB' can reduce the number of lipoproteins and lower the blood cholesterol.Tracy Zimmerman and her colleagues used RNAi in 2006 to reduce the level of 'ApoB' in non-human primates Cynomolgus monkeys.(i) One group of monkeys were given RNAi treatment (Small interfering RNAs, SiRNAs) (doses \\(1 \\mathrm{mg} / \\mathrm{kg}\\) SiRNAs), (ii) Second group of monkeys were given RNAi treatment (doses \\(2.5 \\mathrm{mg} / \\mathrm{kg}\\) SiRNAs), and (iii) Third group of monkeys were injected saline as control.The results of the experiments are illustrated in the graph given below :\n\nName the category of organisms in the living world, where RNA interference (RNAi) takes place. Why? 📲 PW App Link - https://bit.ly/YTAI_PWAP 🌐 PW Website - https://www.pw.live/



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