Duration: 9:29

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One of Canada's best loved actresses has entered the world of science fiction. Sarah Polley stars in Splice, a sci-fi thriller about two young scientists who begin including human DNA in their splicing of animal genes. What happens is an experiment that goes horribly wrong due to the stubbornness and curiosity of Polley's character, Elsa. The film also co-stars Oscar winner Adrien Brody.

Tribute's Bonnie Laufer spoke exclusively with Sarah about the realities of gene splicing and taking on a character unlike anything she has ever done before. We also get the scoop on Polley's next directing project that will star Seth Rogen and Michelle Williams.