Top 100 The Binding of Isaac Videos With The Most Comments by LobosJrTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.Lobos Plays The Binding of Isaac54The Binding of Isaac 2.The Luck of Isaac35The Binding of Isaac 3.Binding of Isaac Glitch Strats25The Binding of Isaac 4.Binding of Isaac - Mom's Heart in 12:51 (boilr rules)21The Binding of Isaac 5.Binding of Isaac - First Cathedral Clear! D6 Unlocked!17The Binding of Isaac 6.Lobos Plays The Binding of Isaac - First Mom Kill!16The Binding of Isaac 7.Lobos Plays The Binding of Isaac - First Satan Kill!16The Binding of Isaac 8.AGDE 2014 - Binding of Isaac15The Binding of Isaac Top 100 » 200 » 300 » 400 » 500