| 1. | Let's Play: The Binding of Isaac Episode 1 - El Gato Supremo | 5,824 | Let's Play | The Binding of Isaac
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| 2. | Tutorial 101: Recording The Binding of Isaac with Fraps | 4,400 | Tutorial | The Binding of Isaac
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| 3. | AGNB Plays: The Binding of Isaac - Episode 166 | 2,577 | | The Binding of Isaac
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| 4. | Let's Play: The Binding of Isaac Episode 8 - I Am ERROR | 1,165 | Let's Play | The Binding of Isaac
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| 5. | AGNB Plays: The Binding of Isaac - Episode 168 | 1,070 | | The Binding of Isaac
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| 6. | Let's Play: The Binding of Isaac Episode 3 - Cooking with Eve | 880 | Let's Play | The Binding of Isaac
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| 7. | Let's Play: The Binding of Isaac Episode 2 - Laser Cats | 869 | Let's Play | The Binding of Isaac
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| 8. | Let's Play: The Binding of Isaac Episode 103 - My Little Pony | 786 | Let's Play | The Binding of Isaac
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| 9. | AGNB Plays: The Binding of Isaac - Episode 164 | 715 | | The Binding of Isaac
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| 10. | SPECIAL ISAAC EPISODE: Using a webcam in game | 684 | | The Binding of Isaac
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| 11. | Let's Play: The Binding of Isaac Episode 43 - NEVA LOSE | 588 | Let's Play | The Binding of Isaac
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| 12. | AGNB Plays: The Binding of Isaac - Episode 167 | 572 | | The Binding of Isaac
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| 13. | Let's Play: The Binding of Isaac Episode 110 - All about Eve | 504 | Let's Play | The Binding of Isaac
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| 14. | Let's Play: The Binding of Isaac Episode 15 - The Cat Came Back | 494 | Let's Play | The Binding of Isaac
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| 15. | Let's Play: The Binding of Isaac Episode 16 - I Got 99 Problems | 472 | Let's Play | The Binding of Isaac
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| 16. | Let's Play: Special 100th Episode - The Breaking of Isaac | 431 | Show | The Binding of Isaac
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| 17. | Let's Play: The Binding of Isaac Episode 32 - OF ALL THE BOSSES | 413 | Let's Play | The Binding of Isaac
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| 18. | Let's Play: The Binding of Isaac Episode 121 - Sassy Sally | 413 | Let's Play | The Binding of Isaac
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| 19. | How hard can The Purist be? | 408 | | The Binding of Isaac
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| 20. | Let's Play: The Binding of Isaac Episode 67 - A Bloated Corpse | 390 | Let's Play | The Binding of Isaac
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| 21. | Let's Play: The Binding of Isaac Episode 127 - Horf Horf Horf | 357 | Let's Play | The Binding of Isaac
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| 22. | AGNB Plays: The Binding of Isaac - Episode 165 | 357 | | The Binding of Isaac
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| 23. | Let's Play: The Binding of Isaac Episode 5 - Milk was a bad choice | 336 | Let's Play | The Binding of Isaac
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| 24. | AGNB Plays: The Binding of Isaac - Episode 162 | 318 | | The Binding of Isaac
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| 25. | SPECIAL ISAAC EPISODE: Mic problems and a lot of luck | 315 | Show | The Binding of Isaac
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| 26. | Let's Play: The Binding of Isaac Episode 4 - Enjoy the Silence | 298 | Let's Play | The Binding of Isaac
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| 27. | Let's Play: The Binding of Isaac Episode 13 - Isaac is a whore | 297 | Let's Play | The Binding of Isaac
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| 28. | Let's Play: The Binding of Isaac Episode 7 - THE 1UP WAS A LIE | 282 | Let's Play | The Binding of Isaac
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| 29. | Let's Play: The Binding of Isaac Episode 70 - Toe Socks | 278 | Let's Play | The Binding of Isaac
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| 30. | Let's Play: The Binding of Isaac Episode 124 - Gimme Gimme | 270 | Let's Play | The Binding of Isaac
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| 31. | Let's Play: The Binding of Isaac Episode 138 - SURPRISE! | 266 | Let's Play | The Binding of Isaac
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| 32. | Let's Play: The Binding of Isaac Episode 29 - Characters without Character | 264 | Let's Play | The Binding of Isaac
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| 33. | Let's Play: The Binding of Isaac Episode 27 - I DID IT DAD | 262 | Let's Play | The Binding of Isaac
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| 34. | Let's Play: The Binding of Isaac Episode 94 - SHIFT KEY | 262 | Let's Play | The Binding of Isaac
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| 35. | Let's Play: The Binding of Isaac Episode 51 - OH BOY | 256 | Let's Play | The Binding of Isaac
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| 36. | Let's Play: The Binding of Isaac Episode 117 - Drunk Boy | 252 | Let's Play | The Binding of Isaac
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| 37. | AGNB Plays: The Binding of Isaac - Episode 161 | 248 | | The Binding of Isaac
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| 38. | Let's Play: The Binding of Isaac Episode 12 - I can't have nice things | 247 | Let's Play | The Binding of Isaac
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| 39. | Let's Play: The Binding of Isaac Episode 123 - SMOOTH MOVES SAMSON | 242 | Let's Play | The Binding of Isaac
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| 40. | A TRUE MIRACLE (ﾉ◕ヮ◕)ﾉ*:･ﾟ✧ | 242 | | The Binding of Isaac
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| 41. | Let's Play: The Binding of Isaac Episode 30 - Qualms | 240 | Let's Play | The Binding of Isaac
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| 42. | Let's Play: The Binding of Isaac Episode 126 - Doctor Nun Cat | 240 | Let's Play | The Binding of Isaac
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| 43. | Special 500 Subscriber Isaac: GARBAGE DAY | 240 | | The Binding of Isaac
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| 44. | Let's Play: The Binding of Isaac Episode 21 - MY LIFE IS A FART | 239 | Let's Play | The Binding of Isaac
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| 45. | AGNB Plays: The Binding of Isaac - Episode 163 | 236 | | The Binding of Isaac
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| 46. | Let's Play: The Binding of Isaac Episode 129 - Volatile | 232 | Let's Play | The Binding of Isaac
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| 47. | Let's Play: The Binding of Isaac Episode 6 - 40/40 Hindsight | 230 | Let's Play | The Binding of Isaac
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| 48. | Let's Play: The Binding of Isaac Episode 19 - Fool Me Twice | 230 | Let's Play | The Binding of Isaac
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| 49. | Let's Play: The Binding of Isaac Episode 10 - Screw you Satan! | 229 | Let's Play | The Binding of Isaac
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| 50. | Let's Play: The Binding of Isaac Episode 18 - Self Sabotage | 227 | Let's Play | The Binding of Isaac
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| 51. | Let's Play: The Binding of Isaac Episode 89 - Angel of Death | 222 | Let's Play | The Binding of Isaac
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| 52. | Let's Play: The Binding of Isaac Episode 9 - TAYLOR SUCKS | 221 | Let's Play | The Binding of Isaac
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| 53. | Let's Play: The Binding of Isaac Episode 122 - Part DUH | 216 | Let's Play | The Binding of Isaac
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| 54. | Let's Play: The Binding of Isaac Episode 148 - Eternal Suffering | 215 | Let's Play | The Binding of Isaac
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| 55. | Let's Play: The Binding of Isaac Episode 34 - Let's Get Physical | 214 | Let's Play | The Binding of Isaac
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| 56. | Let's Play: The Binding of Isaac Episode 115 - GOTTA GO FAST | 209 | Let's Play | The Binding of Isaac
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| 57. | Let's Play: The Binding of Isaac Episode 33 - Like A Boss | 206 | Let's Play | The Binding of Isaac
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| 58. | Let's Play: The Binding of Isaac Episode 118 - Too Dapper | 202 | Let's Play | The Binding of Isaac
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| 59. | Let's Play: The Binding of Isaac Episode 14 - Tipsy | 202 | Let's Play | The Binding of Isaac
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| 60. | Let's Play: The Binding of Isaac Episode 73 - The Deadliest Cankles | 198 | Let's Play | The Binding of Isaac
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| 61. | Let's Play: The Binding of Isaac Episode 134 - I'M DRUNK | 198 | Let's Play | The Binding of Isaac
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| 62. | Let's Play: The Binding of Isaac Episode 93 - Dear Diary | 197 | Let's Play | The Binding of Isaac
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| 63. | Let's Play: The Binding of Isaac Episode 36 - Don't Hug The Fire | 196 | Let's Play | The Binding of Isaac
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| 64. | Let's Play: The Binding of Isaac Episode 120 - Hemophiliac | 193 | Let's Play | The Binding of Isaac
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| 65. | Let's Play: The Binding of Isaac Episode 113 - Blue Balled | 193 | Let's Play | The Binding of Isaac
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| 66. | Let's Play: The Binding of Isaac Episode 11 - Light Tragedies | 193 | Let's Play | The Binding of Isaac
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| 67. | Let's Play: The Binding of Isaac Episode 66 - Cat From Hell | 192 | Let's Play | The Binding of Isaac
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| 68. | Let's Play: The Binding of Isaac Episode 37 - Premature Execution | 190 | Let's Play | The Binding of Isaac
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| 69. | Let's Play: The Binding of Isaac Episode 35 - A Fresh Start | 189 | Let's Play | The Binding of Isaac
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| 70. | Let's Play: The Binding of Isaac Episode 84 - Drunken Master | 187 | Let's Play | The Binding of Isaac
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| 71. | Let's Play: The Binding of Isaac Episode 77 - Bizarro | 185 | Let's Play | The Binding of Isaac
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| 72. | Let's Play: The Binding of Isaac Episode 20 - Never Ending Torment | 185 | Let's Play | The Binding of Isaac
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| 73. | Let's Play: The Binding of Isaac Episode 40 - Judas Rising | 184 | Let's Play | The Binding of Isaac
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| 74. | Let's Play: The Binding of Isaac Episode 28 - Best Day Ever | 183 | Let's Play | The Binding of Isaac
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| 75. | Let's Play: The Binding of Isaac Episode 88 - Technical Foul | 182 | Let's Play | The Binding of Isaac
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| 76. | Let's Play: The Binding of Isaac Episode 22 - Heavenly Sent | 180 | Let's Play | The Binding of Isaac
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| 77. | Let's Play: The Binding of Isaac Episode 111 - The Final Countdown | 179 | Let's Play | The Binding of Isaac
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| 78. | Let's Play: The Binding of Isaac Episode 26 - Run Isaac Run | 179 | Let's Play | The Binding of Isaac
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| 79. | Let's Play: The Binding of Isaac Episode 71 - Spiders are OP | 177 | Let's Play | The Binding of Isaac
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| 80. | Let's Play: The Binding of Isaac Episode 59 - Edmund is watching you | 174 | Let's Play | The Binding of Isaac
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| 81. | Let's Play: The Binding of Isaac Episode 17 - The Purist | 173 | Let's Play | The Binding of Isaac
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| 82. | Let's Play: The Binding of Isaac Episode 90 - The Worst | 173 | Let's Play | The Binding of Isaac
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| 83. | Let's Play: The Binding of Isaac Episode 53 - I Broke Mom | 172 | Let's Play | The Binding of Isaac
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| 84. | Let's Play: The Binding of Isaac Episode 23 - 10 Times as slick | 171 | Let's Play | The Binding of Isaac
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| 85. | Let's Play: The Binding of Isaac Episode 69 - Oh So Fine | 170 | Let's Play | The Binding of Isaac
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| 86. | Let's Play: The Binding of Isaac Episode 57 - Long Story Short | 169 | Let's Play | The Binding of Isaac
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| 87. | Let's Play: The Binding of Isaac Episode 82 - Hibernation Funk | 168 | Let's Play | The Binding of Isaac
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| 88. | Let's Play: The Binding of Isaac Episode 74 - Gruesome Twosome | 168 | Let's Play | The Binding of Isaac
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| 89. | Let's Play: The Binding of Isaac Episode 41 - Just Terrible | 166 | Let's Play | The Binding of Isaac
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| 90. | Let's Play: The Binding of Isaac Episode 86 - Glass Cannon | 163 | Let's Play | The Binding of Isaac
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| 91. | Let's Play: The Binding of Isaac Episode 101 - OOPS | 161 | Let's Play | The Binding of Isaac
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| 92. | AGNB Plays: The Binding of Isaac - Episode 160 | 161 | Let's Play | The Binding of Isaac
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| 93. | Let's Play: The Binding of Isaac Episode 112 - Warpath | 156 | Let's Play | The Binding of Isaac
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| 94. | Let's Play: The Binding of Isaac Episode 130 - CHICKEN WANGZ | 155 | Let's Play | The Binding of Isaac
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| 95. | Let's Play: The Binding of Isaac Episode 159 - Horsepower | 155 | Let's Play | The Binding of Isaac
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| 96. | Let's Play: The Binding of Isaac Episode 38 - Double Trouble | 154 | Let's Play | The Binding of Isaac
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| 97. | Let's Play: The Binding of Isaac Episode 109 - HATE | 152 | Let's Play | The Binding of Isaac
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| 98. | Let's Play: The Binding of Isaac Episode 107 - Bleh | 152 | Let's Play | The Binding of Isaac
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| 99. | Let's Play: The Binding of Isaac Episode 102 - Heart Attack | 150 | Let's Play | The Binding of Isaac
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| 100. | Let's Play: The Binding of Isaac Episode 95 - THE GREATEST ACHIEVEMENT | 150 | Let's Play | The Binding of Isaac
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