| 201. | First Forgotten Challenge! - Custom Afterbirth+ Challenge | 576 | | The Binding of Isaac: Rebirth
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| 202. | Vanishing Twin Challenge Attempt #2 | 574 | | The Binding of Isaac: Rebirth
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| 203. | Learning the BASICS - Hutts Plays Nuclear Throne Ep2 | 573 | Let's Play | Nuclear Throne
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| 204. | 20/20 #2 | 573 | | The Binding of Isaac: Rebirth
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| 205. | ANTIBIRTH Challenge - Scat Man | 573 | | The Binding of Isaac: Rebirth
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| 206. | Tainted Apollyon, Greedier Mode | 571 | | The Binding of Isaac: Rebirth
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| 207. | Man Sacrifices Cat for Good Run - Road to 3000000% [Episode 9] | 569 | | The Binding of Isaac: Rebirth
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| 208. | EXIT THE GUNGEON - First Look! | 569 | | Exit the Gungeon
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| 209. | The LOCKED - Afterbirth+ Mod | 569 | | The Binding of Isaac: Rebirth
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| 210. | Every Enemy is DOUBLED - Custom Afterbirth+ Challenge | 568 | | The Binding of Isaac: Rebirth
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| 211. | WITNESS Final Boss - The Binding of Isaac ANTIBIRTH | 566 | | The Binding of Isaac: Rebirth
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| 212. | Tainted Jacob is ANXIETY | 566 | | The Binding of Isaac: Rebirth
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| 213. | I QUIT MY JOB FOR YOUTUBE | 565 | |
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| 214. | NULL - The Binding of Isaac ALPHABIRTH Mod Pack | 561 | Let's Play | The Binding of Isaac: Rebirth
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| 215. | The Binning Off Isek: Aferberts - Afterbirth Mods | 560 | | The Binding of Isaac: Rebirth
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| 216. | Tainted Lost - Journey to THE BEAST | 559 | | The Binding of Isaac: Rebirth
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| 217. | Modded Character, JOB! | 558 | | The Binding of Isaac: Rebirth
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| 218. | Hutts Uncuts - Best Greed Mode Start #3 | 555 | | The Binding of Isaac: Rebirth
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| 219. | Every Item is SOLDIER SYRINGE - Modded Risk of Rain 2 | 552 | | Risk of Rain 2
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| 220. | Everything to Know About REPENTANCE! - Interview with Edmund McMillen | 549 | | The Binding of Isaac: Rebirth
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| 221. | Stardew Meets Gungeon in ATOMICROPS | 546 | | Atomicrops
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| 222. | Hutts Uncuts: Tainted Lilith | 545 | | The Binding of Isaac: Rebirth
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| 223. | To Hell and Back! - Antibirth | 543 | | To Hell and Back
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| 224. | Infinite CHAOS CARDS - Afterbirth+ Custom Challenge | 543 | | The Binding of Isaac: Rebirth
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| 225. | Nothing but TRINKETS! - Pica Run (Repentance Challenge) | 541 | | The Binding of Isaac: Rebirth
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| 226. | It's so hard... - Haydee Ep.2 | 541 | |
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| 227. | Binding of Isaac MEETS Plants VS Zombies! | 538 | | Plants vs. Zombies
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| 228. | This New Character is Insane... | 538 | | The Binding of Isaac: Rebirth
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| 229. | Every Item is HUSHY | 538 | | The Binding of Isaac: Rebirth
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| 230. | Keeper VS Ultra Greedier - The Binding of Isaac Afterbirth+ | 538 | | The Binding of Isaac: Rebirth
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| 231. | Seeing Double - Repentance Challenge Run | 538 | | The Binding of Isaac: Rebirth
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| 232. | .25 Speed Mega Satan SpeedRun - Speed of SNAILS Challenge | 537 | | The Binding of Isaac: Rebirth
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| 233. | Too Many Knives! - Road to 3000000% [Episode 5] | 533 | | The Binding of Isaac: Rebirth
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| 234. | Duct Tape Every Weapon #7 | 531 | | Enter the Gungeon
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| 235. | Every Item is VIRGIL (Horrible Challenge) - Custom Afterbirth+ Challenge | 531 | | The Binding of Isaac: Rebirth
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| 236. | Hutts is too lucky to be left ALIVE | 527 | | The Binding of Isaac: Rebirth
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| 237. | Penny Pincher - Afterbirth+ Custom Challenge | 527 | | The Binding of Isaac: Rebirth
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| 238. | Lost to Witness - Doing the Impossible! - Antibirth | 521 | | The Binding of Isaac: Rebirth
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| 239. | Every Item is LIL DELIRIUM - Custom Afterbirth+ Challenge | 521 | | The Binding of Isaac: Rebirth
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| 240. | SIREN - Afterbirth+ Mod | 520 | | The Binding of Isaac: Rebirth
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| 241. | Hardest Song? Undertale, Portal, Zelda and MORE! (Patron Pick #5) | 520 | | Undertale
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| 242. | Q&A with Hutts | 519 | |
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| 243. | THE WORST ISAAC MODS 5 | 515 | | The Binding of Isaac: Rebirth
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| 244. | FLAMETHROWER BREAK - The Binding of Isaac Revelations | 513 | | The Binding of Isaac: Rebirth
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| 245. | Angy Azazel - Antibirth | 512 | | The Binding of Isaac: Rebirth
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| 246. | Every Item is TWISTED PAIR | 511 | | The Binding of Isaac: Rebirth
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| 247. | Tainted Eden is STRESS PT2 | 511 | | The Binding of Isaac: Rebirth
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| 248. | Devil's Harvest (1) - Afterbirth+ Modpack | 510 | | The Binding of Isaac: Rebirth
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| 249. | Dad's Stache+ | 506 | | The Binding of Isaac: Rebirth
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| 250. | Instant Karma Challenge - Custom Afterbirth+ Challenge | 505 | | The Binding of Isaac: Rebirth
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| 251. | Inscryption Part 3 - I'm Crushed | 499 | | Inscryption
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| 252. | Delete This Challenge (Attempt #5) | 498 | | The Binding of Isaac: Rebirth
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| 253. | THE WORST ISAAC MODS 2 | 497 | | The Binding of Isaac: Rebirth
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| 254. | THE TRUE ENDING - Hollow Knight Ep.19 | 497 | | Hollow Knight
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| 255. | Toughest Roguelite 2021? - Skul [1.0 Release] | 492 | | Skul: The Hero Slayer
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| 256. | ZERO SHOT SPEED? - Gungeon Custom Challenge | 492 | | Enter the Gungeon
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| 257. | The Binding of Isaac Rebirth Prequel? Sequel? | 491 | | The Binding of Isaac: Rebirth
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| 258. | Breaking the Fire Rate Cap with CAPRICORN | 491 | | The Binding of Isaac: Rebirth
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| 259. | LUNGS OF AN ANGEL - Custom Afterbirth Challenge | 490 | | The Binding of Isaac: Rebirth
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| 260. | Throne Time - Nuclear Throne Ep7 | 489 | | Nuclear Throne
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| 261. | Duct Tape Every Weapon #4 | 489 | | Enter the Gungeon
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| 262. | ROCKET LAUNCHER SYNERGYYYYYYYYYYYYY - The Binding of Isaac Antibirth | 489 | | The Binding of Isaac: Rebirth
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| 263. | Isaac's Awakening - Repentance Challenge | 488 | | The Binding of Isaac: Rebirth
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| 264. | What if Lost Could Use RED HEARTS? | 486 | | The Binding of Isaac: Rebirth
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| 265. | Inscryption Part 2 - I'm HOOKED | 484 | | Inscryption
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| 266. | JEDI Transformation? - The Binding of Isaac ANTIBIRTH | 484 | | The Binding of Isaac: Rebirth
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| 267. | Bee Transformation! - Ipecac Community Mod | 483 | | The Binding of Isaac: Rebirth
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| 268. | Hypochondriac - Custom Afterbirth Challenge (PILLS) | 482 | | The Binding of Isaac: Rebirth
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| 269. | Every Item is BOILED BABY | 482 | | The Binding of Isaac: Rebirth
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| 270. | r/HuttsGaming Subreddit Review | 480 | Review |
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| 271. | Family Man Challenge PART 2 - Road to 3000000% [Episode 7] | 480 | | The Binding of Isaac: Rebirth
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| 272. | Bertran in REPENTANCE! (Busted Run) | 478 | | The Binding of Isaac: Rebirth
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| 273. | I Don't Know What I'm Doing | 478 | |
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| 274. | Road to 3000000% | 478 | | The Binding of Isaac: Rebirth
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| 275. | Slightly Annoying Challenge | 478 | | The Binding of Isaac: Rebirth
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| 276. | TOUGH LESSONS - Nuclear Throne Ep4 | 477 | | Nuclear Throne
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| 277. | The Binding of Isaac: Four Souls - UNBOXING | 477 | | The Binding of Isaac
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| 278. | MONSTRO MODE | 473 | | The Binding of Isaac: Rebirth
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| 279. | TOAD TIME - Afterbirth+ Insane Mode | 473 | | The Binding of Isaac: Rebirth
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| 280. | Destruction via Maggie - Road to 3000000% [Episode 3] | 472 | | The Binding of Isaac: Rebirth
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| 281. | Bloody Mary Challenge | 472 | | The Binding of Isaac: Rebirth
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| 282. | FLYSAAC - Devil's Harvest Afterbirth+ Modpack (2) | 471 | | The Binding of Isaac: Rebirth
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| 283. | REVELATIONS CHAPTER 2 | 471 | | The Binding of Isaac: Rebirth
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| 284. | Solar System 2.0 - Custom Afterbirth Challenge | 471 | | The Binding of Isaac: Rebirth
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| 285. | Maggie's Last Unlock! | 471 | | The Binding of Isaac: Rebirth
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| 286. | GODMODE - The Binding of Isaac Afterbirth Mod [Drake] | 470 | | The Binding of Isaac: Rebirth
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| 287. | The Next Big Deckbuilder? | 470 | | Neoverse
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| 288. | LIL HUNTER SHOWDOWN - Nuclear Throne Ep3 | 470 | | Nuclear Throne
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| 289. | CABBAGE REVENGE - Custom Afterbirth+ Challenge | 470 | | The Binding of Isaac: Rebirth
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| 290. | EVERY VEGETABLE CHALLENGE - Custom Afterbirth+ Challenge | 470 | | The Binding of Isaac: Rebirth
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| 291. | Every Item is LIL LARRY | 469 | | The Binding of Isaac: Rebirth
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| 292. | Rainbow Mode Mod - Enter the Gungeon Custom Run | 468 | | Enter the Gungeon
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| 293. | ADAM Modded Character - Afterbirth+ | 465 | | The Binding of Isaac: Rebirth
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| 294. | RAT SHOWDOWN - Enter the Gungeon Advanced Gungeons and Draguns UPDATE | 465 | Vlog | Enter the Gungeon
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| 295. | Custom Isaac Story Challenge | 464 | | The Binding of Isaac: Rebirth
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| 296. | Only Items from CHESTS - Afterbirth+ Custom Challenge | 463 | | The Binding of Isaac: Rebirth
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| 297. | The Binding of UNDERTALE OMEGA FLOWEY FIGHT- Afterbirth Mods [1] | 463 | | The Binding of Isaac: Rebirth
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| 298. | Every Item Is RED STEW | 462 | | The Binding of Isaac: Rebirth
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| 299. | The Greening of Isaac: Regreen'd | 462 | | The Binding of Isaac: Rebirth
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| 300. | Amazing but IMPOSSIBLE Challenge - Fiend Folio | 458 | | The Binding of Isaac: Rebirth
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