1. | IS RED KEY GOOD? | Exploring all 165 rooms on Basement I... | 17,492 | | The Binding of Isaac: Rebirth
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2. | The HISTORY of the Binding of Isaac! | [ Original to Repentance ] | 15,542 | | The Binding of Isaac: Rebirth
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3. | The HISTORY of the Keeper in the Binding of Isaac! [Original to Repentance] | 12,635 | | The Binding of Isaac: Rebirth
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4. | Every Time I Get Hit, the Roguelike Changes | 11,760 | | Spelunky
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5. | 101 Facts and Tips for The Binding of Isaac: Afterbirth+ | 10,589 | | The Binding of Isaac: Rebirth
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6. | TOP 10 BRIMSTONE SYNERGIES! [Binding of Isaac: Afterbirth+] | 10,327 | | The Binding of Isaac: Rebirth
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7. | 101 MORE Facts about The Binding of Isaac AFTERBIRTH+! | 8,956 | | The Binding of Isaac: Rebirth
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8. | TOP 10 WORST ITEMS IN AFTERBIRTH + ! | 7,705 | | The Binding of Isaac: Rebirth
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9. | TOP 10 SYNERGIES FOR 'THE FORGOTTEN'! | 7,433 | | The Binding of Isaac: Rebirth
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10. | TOP 20 SOY MILK SYNERGIES IN AFTERBIRTH+! | 7,235 | | The Binding of Isaac: Rebirth
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11. | The BEST BRIMSTONE SYNERGIES in the Binding of Isaac: REPENTANCE! | 6,955 | | The Binding of Isaac: Rebirth
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12. | This UNKNOWN Roguelike has 98% Positive Reviews | 6,458 | Review | Brutal Orchestra
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13. | TOP 10 SOY MILK SYNERGIES! [Binding of Isaac: AFTERBIRTH +] | 5,909 | | The Binding of Isaac: Rebirth
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14. | HOW TO BREAK THE GAME! [Binding of Isaac Afterbirth+ In Depth Guide] **OUTDATED FOR REPENTANCE** | 4,800 | Guide | The Binding of Isaac: Rebirth
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15. | TOP 10 LUDOVICO TECHNIQUE SYNERGIES! | 4,710 | | The Binding of Isaac: Rebirth
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16. | TOP 10 TINY PLANET SYNERGIES! | 4,550 | | The Binding of Isaac: Rebirth
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17. | Every Time I Get Hit, MORE Roguelikes Change | 4,530 | | Dead Cells
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18. | TOP 10 MOM'S KNIFE SYNERGIES in AFTERBIRTH+! | 4,483 | | The Binding of Isaac: Rebirth
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19. | FIRST REPENTANCE GAMEPLAY LOOK! | Binding of Isaac: Repentance News | 4,408 | | The Binding of Isaac: Rebirth
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20. | ALL 161 ITEM BALANCE CHANGES IN THE BINDING OF ISAAC: REPENTANCE! | 4,080 | | The Binding of Isaac: Rebirth
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21. | 10 FUN ISAAC SYNERGIES! | Binding of Isaac: Afterbirth+ | 4,036 | | The Binding of Isaac: Rebirth
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22. | WHAT IS THE BEST ITEM IN REPENTANCE? | 3,981 | | The Binding of Isaac: Rebirth
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23. | Can you Beat The Password Game? | 3,954 | |
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24. | This is an Extremely Unique New Strategy Roguelike | 3,852 | |
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25. | TOP 15 DEVIL DEAL ITEMS in The Binding of Isaac: AFTERBIRTH+! | 3,812 | | The Binding of Isaac: Rebirth
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26. | TOP 15 ANGEL DEAL ITEMS in AFTERBIRTH+! | 3,657 | | The Binding of Isaac: Rebirth
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27. | I'm Addicted to Minimalistic Farming Roguelikes | 3,408 | |
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28. | TOP 10 *NEW* SYNERGIES in REPENTANCE! | 3,340 | | The Binding of Isaac: Rebirth
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29. | This Roguelike is a MUST PLAY Hidden Gem | 3,308 | | The Void Rains Upon Her Heart
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30. | EVERY ITEM IN BOOSTER PACK 5! | Binding of Isaac Afterbirth+ | 3,200 | | The Binding of Isaac: Rebirth
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31. | This is the BEST Tactical Roguelike of 2023 | 3,107 | Show | Shogun Showdown
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32. | Top 10 HATED BOSSES! :: Binding of Isaac: AFTERBIRTH | 2,962 | | The Binding of Isaac: Rebirth
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33. | HOW TO BECOME INVINCIBLE! BEST SYNERGY! :: Binding of Isaac: AFTERBIRTH + | 2,941 | Tutorial | The Binding of Isaac: Rebirth
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34. | BINDING OF ISAAC: REPENTANCE COMES SOON | [ 2020 Repentance News Video ] | 2,896 | | The Binding of Isaac: Rebirth
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35. | 100+ DAMAGE?! NEW CADAVER CHARACTER! | Repentance Mod Spotlights | 2,878 | | The Binding of Isaac: Rebirth
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36. | WHAT IS A ROGUELIKE? [Roguelike vs Roguelite] | 2,756 | | The Binding of Isaac
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37. | UNLOCKING THE FORGOTTEN! :: Binding of Isaac Afterbirth+ [Booster Pack 5] | 2,724 | Tutorial | The Binding of Isaac: Rebirth
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38. | RANKING ALL 34 CHARACTERS IN THE BINDING OF ISAAC: REPENTANCE... | 2,687 | | The Binding of Isaac: Rebirth
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39. | WE WENT INFINITE! | Luck be a Landlord | 2,589 | | Luck be a Landlord
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40. | The Full Release of AK-xolotl is FINALLY Here | 2,585 | | AK-xolotl
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41. | This Hidden Gem Bullet Hell Could Be the Next Big Roguelike | 2,526 | |
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42. | This is the Best Game I've Played in 2023 | 2,500 | Review |
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43. | This is the Sneaky Strategy Roguelike of the Year | 2,460 | |
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44. | it's that mod you all want me to play | 2,450 | | The Binding of Isaac: Rebirth
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45. | HOW TO GET -1 FIRE RATE! EVERYTHING ABOUT TEARS! :: In Depth Isaac :: 1 | 2,435 | | The Binding of Isaac: Rebirth
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46. | THE JOURNEY BEGINS! | The Binding of Isaac: REPENTANCE | 2,402 | | The Binding of Isaac: Rebirth
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47. | Interviewing the creator of Isaac, Edmund McMillen, about Repentance and MORE! | 2,394 | | The Binding of Isaac: Rebirth
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48. | 28 RATE OF FIRE?! NEW CHARACTER, JOB! | Repentance Mod Spotlights | 2,300 | | The Binding of Isaac: Rebirth
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49. | JOKER IS OVERPOWERED! | Luck be a Landlord | 2,283 | | Luck be a Landlord
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50. | TOP 10 BUTTER BEAN SYNERGIES in AFTERBIRTH+! | 2,184 | | The Binding of Isaac: Rebirth
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51. | TOP 10 ITEMS TO LOOK FORWARD TO IN REPENTANCE! | 2,176 | | The Binding of Isaac: Rebirth
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52. | This Roguelike is The Binding of Isaac... but Grosser | 2,151 | | The Binding of Isaac
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53. | 25 Facts You May Not Have Known About the Binding of Isaac AFTERBIRTH | 2,145 | | The Binding of Isaac: Rebirth
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54. | They've Made the PERFECT Roguelike Game | 2,099 | |
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55. | HOW TO GET 25,000 DAMAGE! :: In Depth Isaac: Damage | 2,069 | | The Binding of Isaac: Rebirth
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56. | This Amazing Roguelike Became MORE Amazing | 2,850 | |
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57. | This is My Most Anticipated Roguelike of the Year | 2,011 | |
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58. | THE ULTIMATE WHEEL OF ISAAC! | 1,995 | | The Binding of Isaac: Rebirth
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59. | 400+ NEW ITEMS, NEW CHARACTERS, AND MORE! | Ultra Modded Isaac | 1,989 | | The Binding of Isaac: Rebirth
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60. | What are PLANETARIUMS? [ REPENTANCE / ANTIBIRTH ] | 1,966 | | The Binding of Isaac: Rebirth
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61. | HOW TO GIVE ITEMS! :: Binding of Isaac: Debug Console Tutorials :: 1 | 1,963 | Tutorial | The Binding of Isaac: Rebirth
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62. | FIRST BROKEN RUN! | Luck be a Landlord | 1,887 | | Luck be a Landlord
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63. | Every Time I Get Hit, the Game Changes to a MORE OBSCURE Roguelike | 1,844 | | The Binding of Isaac
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64. | BINDING OF ISAAC REPENTANCE NEWS! | Late 2020 Release Date **OUTDATED** | 1,817 | | The Binding of Isaac: Rebirth
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65. | 150+ NEW ITEMS, 3000+ NEW ROOMS AND MORE! | Unstable Modded Eden Streaks | 1,805 | | The Binding of Isaac: Rebirth
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66. | This New Tower Defense Autobattler is Pure Sneaky Fun | 1,782 | |
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67. | WHAT IF EVERY FLOOR HAD ITS OWN ITEM POOL? (ft. @bd1pLP) | 1,778 | Let's Play | The Binding of Isaac: Rebirth
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68. | CRABS. That's it, that's the title | Luck be a Landlord | 1,768 | | Luck be a Landlord
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69. | BRAND NEW Binding of Isaac Plants vs. Zombies Game! | I.RULE | 1,752 | | The Binding of Isaac
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70. | How to Use the Debug Console in the Binding of Isaac AFTERBIRTH +! **OUTDATED** | 1,751 | Tutorial | The Binding of Isaac: Rebirth
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71. | EVERYTHING TO KNOW ABOUT EDEN! :: In Depth Isaac :: 2 | 1,743 | | The Binding of Isaac
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72. | This Gambling Roguelike is Chaotic Fun | 1,741 | |
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73. | TOP 10 ORBITALS IN AFTERBIRTH+! | 1,737 | | The Binding of Isaac: Rebirth
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74. | SACRED HEART + BRIMSTONE + TECHNOLOGY?! | The Binding of Isaac: REPENTANCE | 1,723 | | The Binding of Isaac: Rebirth
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75. | NEW LUCK BE A LANDLORD UPDATE! (spoiler: it's actually gamebreaking) | 1,668 | Vlog | Luck be a Landlord
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76. | PERMANENT MONEY IS SO STRONG! | Luck be a Landlord | 1,657 | | Luck be a Landlord
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77. | NEW CHARACTER! MASTEMA! | Repentance Mod Spotlights | 1,637 | | The Binding of Isaac: Rebirth
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78. | This New Gamebreaking Roguelike is Incredible | 1,576 | |
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79. | 25 MORE Facts You May Not Have Known about the Binding of Isaac AFTERBIRTH! | 1,567 | | The Binding of Isaac: Rebirth
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80. | TAINTED MEI! | Binding of Isaac: REPENTANCE Mod Spotlights | 1,560 | | The Binding of Isaac: Rebirth
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81. | This NEW Slot Machine Roguelike is Amazing | 1,527 | |
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82. | THE ULTIMATE OVERPOWERED RUN! | Binding of Isaac: ANTIBIRTH Eden Streaks | 3 | 1,513 | | The Binding of Isaac: Rebirth
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83. | INSANELY STRONG BROKEN RUN! | Binding of Isaac: Revelations Mod Relook | 1 | 1,487 | | The Binding of Isaac: Rebirth
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84. | Every Time I Get Hit, the Roguelike Changes through History | 1,486 | | Spelunky
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85. | THE WHEEL OF ISAAC! | 1,480 | | The Binding of Isaac
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86. | 1,000,000,000 IN ONE SPIN?! NEW UPDATE! | Luck be a Landlord | 1,469 | Vlog | Luck be a Landlord
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87. | 700,000 ITEMS MOD IS BACK! :: Binding of Isaac: Afterbirth+ Mod Spotlights | 1,466 | | The Binding of Isaac: Rebirth
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88. | MOSES CHARACTER! AWESOME TEARS! Repentance Mod Spotlights | 1,455 | | The Binding of Isaac: Rebirth
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89. | MASSIVE MODDED EXPANSION! | Binding of Isaac: FIEND FOLIO | 1 | 1,444 | | The Binding of Isaac: Rebirth
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90. | TOP 10 FAMILIARS! [Binding of Isaac: Afterbirth+] | 1,441 | | The Binding of Isaac: Rebirth
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91. | TOP 10 CURSED EYE SYNERGIES in The Binding of Isaac: AFTERBIRTH+! | 1,433 | | The Binding of Isaac: Rebirth
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92. | MODDED BERTRAN DISASTER! | Repentance Mod Spotlights | 1,427 | | The Binding of Isaac: Rebirth
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93. | Brutal Orchestra is a MUST PLAY Roguelike | 1,417 | | Brutal Orchestra
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94. | WHO NEEDS TEARS? THE GLARE! | Repentance Mod Spotlights | 1,416 | | The Binding of Isaac: Rebirth
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95. | CHECKERED FLAG IS KINDA CRAZY... | Luck be a Landlord | 1,394 | | Luck be a Landlord
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96. | TOP 10 ITEMS ADDED IN AFTERBIRTH + ! | 1,390 | | The Binding of Isaac: Rebirth
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97. | This NEW ROGUELIKE has Captured my Heart | 1,381 | | Beyond the Long Night
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98. | THE ANCIENT LIZARD BLADE! | Luck be a Landlord | 1,375 | | Luck be a Landlord
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99. | Are Chickens the Meta in Farm Keeper? | 1,371 | | Lake
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100. | WHAT IF EVERY ITEM ROOM HAD LIKE, 15 ITEMS? (ft. @bd1pLP ) | 1,347 | Let's Play | The Binding of Isaac: Rebirth
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